Ischemic tolerance exists in many organs, among which the cerebral ischemic tolerance and its potential clinical applications are most notable. The discovery of new triggers of cerebral ischemic tolerance has brought more interesting insights into the molecular mechanisms. The remote ischemic preconditioning and pharmacological induction of cerebral ischemic tolerance have shown promising clinical safety and feasibility, and therefore may be important breakthroughs in the clinical application of cerebral ischemic tolerance.
Brain Ischemia ; physiopathology ; Erythropoietin ; therapeutic use ; Humans ; Ischemic Preconditioning ; methods