104 cases of children with malignant lymphoma in our hospital from June 1966 to June 1986 are reported. 84 were males and 20 females. Their ages ranged 6 to 12. These patients were 33 HD, 71 NHL. 9 in stage Ⅰ, 29 in stage Ⅱ, 37 in stage Ⅲ and 29 in stage Ⅳ. In this series B group was 55% (57/104). The clinical primary site of intranodular was 75% (78/104) and extranodular 25%(26/104). The treatment methods include rrdiotherapy alone 16, chemotherapy alone 27 and combination 61. The complete remission (CR) was 30% (31/104), partial remission (PR) 58% (60/104). Total repose rate was 88%. The overall 3 and 5 year survival rates were 26.3%(24/91) and 18%(15/83). Survivals of 10 years were 6 cases (no evidence of disease). It is indicated that the primary sites, clinical stages, pathology types, treatment methods and complete remission are the prognostic factors in children with malignant lymphoma. Errly diagnosis, clinical stage and treatment have been discussed briefly. It is emphasized that after treatment, follow-up and maitaining chemotherapy may prolong the life of the patients.

Objective To assess the feasibility of real-time Bi-Plane in observing normal mitral annular areas in different gestational ages.Methods Routine two-dimensional echocardiography and real-time Bi-Plane were used to observe mitral structure and measure the mitral annular area in 159 fetuses.Pearson correlation analysis was used to evaluate the correlation of the areas with gestational age.Visualization rates and acquisition time were recorded and analyzed statistically.Resuits The mitral annular areas measured by two techniques were both correlated to the gestational age (r=0.71,0.75,both P＜0.05).There were significant differences in visualization rate (x2 =4.375,P=0.036) of mitral annular area and acquisition time (t=6.11,P＜0.05) between routine two-dimensional echocardiography and real-time Bi-Plane.Conclusion Real-time Bi-Plane technique is direct,accurate,convenient and fast in observing mitral prenatally.By using Bi-Plane technique to measure mitral annular area,abnormal morphology changes of mitral valve can be evaluated,so as to provide great application value for clinic.

Using proliferating inhibition test, the effects of three cultivars of black mushroom on the growth of gastric carcinoma cell in vitro were observed. We have found that the extracts of all three cultivars of black mushroom had inhibiting effects on the growth of tumor cells in medium at some levels, especially Cr-02 was the most evident one.The results suggest that black mushroom has some anti-tumor effects, and it is worthwhile to study farther for verification.

Female ; Humans ; Incontinentia Pigmenti ; diagnosis ; pathology ; therapy ; Infant, Newborn

Adolescent ; Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols ; adverse effects ; therapeutic use ; Drug Combinations ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Hematopoiesis ; drug effects ; Humans ; Leukemia, Myeloid, Acute ; drug therapy ; Male ; Middle Aged ; Phytotherapy ; Schisandraceae

The effect of OQP, a pormula of traditional Chinese medieine belonging to the category "Precription of the Reinforeing Qi and Enriching Blood for keep the Original Qi", on cell strain of human hepatic carcinoma SMMC-7721 was observed. The results showed that OQP depressed the incorporation of both ~3H-TdR and ~(14)C-UR in cells of hepatic carcinoma. This indicated that OQP inhibited the synthesis of DNA and RNA, and the growth of the cancer cell. Such effect may result from the low ratio Cu/Zn and the high content of Se in OQP. In conclusion, in this study it has been demonstrated that OQP can not only improve the general condition of patients in advanced liver cancer and lcukopenia of patients in chemotherapy and radiotherapy, but also can inhibite the growth of the cell of hepatic carcinoma directly.

Objective To establish a method for detection of RhD(+) red blood cells mixed in D-negative blood by flow cytometry(FCM).Method RhD(+) and RhD(-) RBCs were mixed according to predefined ratios.Cells were indirectly labeled,with IgG anti-D labeled as the first antibody,and FITC-anti-IgG F(ab')2 as the second antibody.The percentage of RhD(+) RBCs was determined by FCM,and the best dosage of IgG anti-D was also defined.The ratio of red cells in the two groups,measured by FCM,was compared with the actual ratio.The consistency of method was also evaluated.Results The effective dosage of IgG anti-D was 1∶4,and 50?l/1?106 cells.When the actual percentages of RhD(+) cell among RhD(-) cells were 2.5%-0.312%,the correlation coefficient between the percentages measured by FCM and the actual percentages was 0.987.The same tubes,containing 10% and 2.5% RhD(+) RBCs,were each tested for 10 times,and their coefficient of variation were 3.4%,and 4.9%,respectively.Conclusion The method of quantifying the RhD(+) RBCs in D-negative blood by FCM is feasible and repeatable,which deserves a further clinical application.

Pulmonary hypertension(PH) is a clinical hemodynamic syndrome characterized by elevation of pulmonary artery pressure and pulmonary vascular resistance,which was presumed mainly due to pulmonary vasoconstriction,remodeling of the pulmonary vessel wall,and thrombosis in situ.Endothelin,nitric oxide,and prostacyclin pathway were three major pathways involved in the pathogenesis.Current therapies interfered with these 3 pathways in combination with conventional measures have prolonged length of life of patients and improved their quality of life significantly.

Objective To investigate the clinical efficacy of Zusanli moxibustion intervention in abdominal distention with enteral nutrition after stomach cancer surgery.Methods One hundred patients who had undergone stomach cancer surgery and received postoperative enteral nutrition were randomly allocated to treatment and control groups, 50 cases each. The control group received medication and the treatment group, Zusanli moxibustion in addition. Post-treatment incidences and grading scores of abdominal distention were compared between the two groups.Results The incidence of abdominal distention was 6.0% in the treatment group and 24.0% in the control group; there was a statistically significant difference between the two groups (P<0.05). The grading score of abdominal distention was (0.33±0.58) in the treatment group and (0.92±1.00) in the control group; there was a statistically significant difference between the two groups (P<0.05).Conclusion Zusanli moxibustion can effectively prevent the occurrence of abdominal distention in patients with enteral nutrition after stomach cancer surgery.