1.Fluid therapy in critically ill patients.
Chinese Journal of Surgery 2009;47(6):432-434
2.Pharmacodynamic study on Chanfuan Oral Solution
Jinsong ZHANG ; Hua KANG ; Dong XUE ;
Chinese Traditional Patent Medicine 1992;0(11):-
AIM: To study the pharmacodynamic effect of Chanfuan Oral Solution. METHODS: Acute blood stagnation caused by adrenaline, ankle swelling, ear edema and writhing caused by acetic acid were taken for experiment models. RESULTS: Chanfuan Oral Solution could significantly reduce blood viscosity. Results also showed that it had inhibitory effect on rat's ankle swelling, ear edema and reduction in ratio of writhing of mice. CONCLUSION: These results suggest Chanfuan Oral Solution is an effective drug for reducing blood viscosity, anti inflammation and analgesia.
3.Left ventricular multiple myxomas in a neonate.
Chinese Journal of Pediatrics 2005;43(8):630-630
4.One case of nasal cellular schwannoma.
Rong TONG ; Jiajun YANG ; Kang XUE
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2014;49(11):959-959
Humans
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Neurilemmoma
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diagnosis
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Nose
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Nose Neoplasms
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diagnosis
5.Evaluation of nocturnal hypoglycemia in patients with type 2 diabetes via continuous glucose monitoring system
Yan WANG ; Shouping GUAN ; Ying KANG ; Yuanming XUE
Chinese Journal of Endocrinology and Metabolism 2010;26(5):393-394
The variation of blood glucose in 1 147 patients with type 2 diabetes mellitus was monitored by continuous glucose monitoring system(CGMS). The results showed that the peak hours of nocturnal hypoglycemia occurred during 22 : 00-2 : 00. The incidence of nocturnal hypoglycemia was negatively correlated with mean blood glucose and blood glucose at three hours after supper. The probability of hypoglycemia was up to 50% when blood glucose level had been as low as 4. 7 mmol/L at 3 h after supper.
6.Study of bone marrow T-lymphocyte activation in patients with systemic lupus erythematosus
Xue-Qin DING ; Kang-Xing ZHOU ; Ling-Yun SUN ;
Chinese Journal of Rheumatology 2000;0(06):-
0.05). In active SLE, the CD3~+HLA-DR~+, CD4~+HLA-DR~+ and CD8~+ HLA-DR~+ cells of BM were all higher than those of peripheral blood in the control group(P
7.Study on ventricular-arterial coupling in patients with type 2 diabetes mellitus by ultrasound
Zhaojun LI ; Chunsong KANG ; Jiping XUE ; Kailing SHI ; Xiaoyan CHEN
Chinese Journal of Ultrasonography 2012;21(9):757-761
Objective To study the ventricular-arterial coupling in the patients with type 2 diabetes mellitus (DM) by ultrasound.Methods Eighty patients with DM were divided into 2 groups:normal left ventricular ejection fraction (EF) group (DMN,EF≥50 %,n =40) and abnormal EF group (DMA,EF<50%,n =40).At the same time,42 healthy volunteers were selected as a control group.The left ventricular (LV) relative wall thickness (RWT),mass index (LVMI),stroke volume (SV),stroke works (SW),ratepressure product (RPP),systemic vascular resistance index (SVRI),LV end-systolic elastance (Ees),arterial elastance index (Ea) and ventricular vascular index (VVI) were measured and calculated.Longitudinal strain (LS) of myocardial segment including base(LSBA),papillary muscle (LSPM) and apex (LSAP) were analyzed by two-dimensional speckle tracking imaging.Results (1) Compared with the control,the RWT and LVMI were all increased (P <0.01),but the LSBA,LSPM and LSAP were decreased (P < 0.01) in the DMN and DMA groups (P <0.01).In DMA group,the RWT,LSBA,LSPM and LSAP were decreased (P <0.01).Compared with the DMN group,the LSBA,LSPM and LSAP were decreased in DMN group (P <0.01).(2) Compared with the control,the Ea,VVI,RPP and SVRI were increased,but the Ees was decreased (P <0.05)in DMA group (P <0.01).In the DMN,RPP was increased compared with the control group (P <0.01).Compared with the DMN group,the Ea,VVI,RPP and SVRI were increased,but Ees was decreased in the DMA (P <0.05).(3)The LSBA,LSPM and LSAP were all positively correlated with VVI(P <0.01).Multiple regression analysis showed that the LSAP,RWT,LVMI and SW were independent predictor of VVI (b' =-0.613,-0.290,0.290 and-0.205,P < 0.05).Conclusions The ventricular-arterial coupling is normal in the DMN group,but is abnormal in DNA group.LSAP is independent predictors for ventricular-arterial coupling.
8.Experimental study on effects of captopril on renal perfusion in diabetes mellitus rabbits by contrast-enhanced ultrasound
Jian WANG ; Chunsong KANG ; Kailing SHI ; Jiping XUE ; Ruili WANG
Chinese Journal of Ultrasonography 2012;21(9):803-806
Objective To assess the effects of captopril on renal perfusion of diabetic mellitus(DM)rabbits at early stage by contrast-enhanced ultrasound (CEUS).Methods Of 58 rabbits,6 were control group,37 were made as DM model successfully by alloxan and were randomly divided into 4 groups:untreatment group (n =16) and treatment group A,B and C (n =7 averagely).The treatment groups were given captopril(25 mg/kg weight) everyday by intragastric administration after the DM model established and renal pathology appeared Mogensen DN Ⅰ,Ⅱ or / and Ⅲ respectively.The treatment lasted 12 week.Then CEUS was performed on bilateral kidney to observe the renal perfusion,the parameters included:curve ascending slope(K1),time to peak intensity(PIT),peak signal intensity(PSI),area under the curve(AUC) and time to half of peak intensity(HPT).Results At the end of 12 weeks,compared with control group,PIT and HPT delayed,PSI and K1 decreased in untreatment group and group C,AUC of untreatment group increased.Compared with untreatment group,PIT,HPT and AUC decreased,PSI and K1 increased in group A,B and C.Compared with group C,HPT of treatment group A,B decreased.Compared with control group,renal's size increased and the cortex was thickened in untreatment group and group A,B,C.The pathological examination showed:renal were damaged more seriously in untreatment group than that in group A and B.There was no significant difference in Scr and BUN between all groups.Conclusions Assessment of CEUS for renal perfusion of diabetic mellitus rabbits at early stage is feasible and captopril can improve renal perfusion of DM rabbits.
9.Relation research of the expression and function of VEGF and its receptor
Huafeng KANG ; Xijing WANG ; Xinghuan XUE ; Xiaoxu LIU
Chinese Journal of Tissue Engineering Research 2001;5(21):152-153
Objective We studied the expression of VEGF and its receptor,FLK- 1,in neuroblastoma and its relation to clinical features.Methods With the help of antigen repairing,immunohistochemical analysis using antibody against VEGF,FLK- 1 was carried out on speciments of 52 cases of neuroblastoma.Results There were 36 cases of VEGF and 34 cases of FLK- 1 positive expression,the expression of them were nearly consistent.The positive rate of VEGF and FLK- 1 were higher in metastatic tumors(28/34,26/34)than in non- metastastic tumors and had statistical significance(respectively P<0.01,P<0.05).The expression of VEGF in UH tumors was higher than in FH tumors,and statistical value is significant(P<0.05).Conclusion VEGF is a vital angiogenic factor,and may play an improtant role in the progression and metastasis of neuroblastoma.Its expression and function correlates well to FLK- 1,and may aid in predicting patients at risk of metastasis.
10.The Plasma Vitamin A and Subsets of T Lymphocyte in Lung Cancer Patients
Yuxia ZHAO ; Yanjie LI ; Xue YAN ; Jian KANG ; Runjiang YU
Journal of China Medical University 2001;30(2):133-134
Objective: Our aims were to evaluate the plasma vitamin A status and the function of T-cell dependent immunity in lung cancer patients, so as to explore the correlation between them. Methods:We measured the plasma vitamin A status with HPLC and checked the subsets of T lymphocyte with indirect immunofluorescence technique. Results: The levels of plasma vitamin A in lung cancer patients and in controls were(0.406±0.111)mg/L and(0.548±0.149)mg/L respectively . There was a significant difference between them(P<0.001) . The levels of CD3, CD4,and CD4/CD8 were lower in lung cancer patients than those in controls, while the level of CD8 was higher. The plasma vitamin A had positive correlation with CD3 , CD4,and negative with CD8. Conclusion: There is defect of the plasma vitamin A and low level of the function of T cell dependent immunity in lung cancer patients,which shows the obvious correlation between them. This research supplies the basis of clinical therapy to lung cancer with vitamin A.