Tissue samples from 42 patients with nonepitheliogenie ovarian tumors were assayed for estrogen receptor (ER) and progesterone receptor (PR) by Lce's fluorescent histochemical method. 2 of 4 theca cell tumor, 6 of 8 granulosa cell tumor had ER and PR. Among the 6 cases of granulosa cell tumor, 4 cases exhibited a high level of receptors (ER、PR positsve cell: 40%～50% of total tumor cells). As to teratomas, the epithelial cells of sweat glands, and cylindrical epithelia, as well as chondrocytes were ER PR positive. No ER-and PR-positive cells were found in endodermal sinus tumors, drsgerminomas and fibromas. Of 4 mataststic ovarian tumors, which were from gastrointestinal adenocarcinoma, tbe ER-and PR-positive cells were found in 1 specimen. The findings suggested that hormone-related therapy might be worthy of trying on thc patients with receptor positive granulosa cell tumor.

To investigate whether the laboratory specimens preserved in Beijing Hospital Biobank during a specific period had been contaminated by SARS-Cov-2 through a cross-sectional study, and to establish a retrospective biobank safety screening system. Laboratory specimens were collected from the Department of Respiratory and Critical Care Medicine and the Fever Clinic of Beijing Hospital from November 1, 2019 to January 22, 2020, nucleic acid and serological antibody testing were performed for SARS-CoV-2 in these specimens (including 79 serum, 20 urine, 42 feces and 21 bronchoalveolar lavage fluid specimens). The safety of the stored samples during this period was defined by negative and positive results. Both the nucleic acid test and serological antibody test showed negative for SARS-CoV-2, indicating that these specimens were safely stored in the biobank. High-risk specimens collected in our hospital during the early stage of the COVID-19 outbreak are free of SARS-CoV-2, and a safety screening strategy for the clinical biobank is established to ensure the biosafety of these samples.
Biological Specimen Banks ; COVID-19 ; Cross-Sectional Studies ; Hospitals ; Humans ; Retrospective Studies ; SARS-CoV-2