1.Attach importance to intervention therapy of acute abdomen
Journal of Interventional Radiology 1994;0(04):-
Acute abdomen means a set of clinical emergency with acute abdominalgia as the primary characteristic symptom of onset,including others as the acute onset,quick symptom changes,severe illness,and oftenly need surgical treatment;therefore,acute abdomen ought to be designated within surgery domain.As interventional therapy is extensively applied in clinical medicine,now a days many victims of acute abdomen,especially those with ambiguous clinical diagnosis requiring an initial invasive examination(angiography,PTC,etc),should be referred to interventional therapy before taking an item of invasive measures.This new concept management has achieved good clinical curative effect and become one of the remarkable achievements in acute abdomen therapeutics.Such predominance finds proper expression in the following two aspects:(1)The evolution of contemporary medical iconography has made it possible to duely and accurately diagnose acute abdomen,and thus created a diagnostic predominance for us-interventionalists;(2)Intervention therapy is featured with its unigue minimal invasion and massive effectiveness,and thus provides high leading edge than conventional surgical operation.We believe that intervention management ought to become the first-choice for treating the above mentioned acute abdomen.(J Intervent Radiol,2006,15:193-194)
2.Experience of Guaranteeing Medical Supplies in the State of Emergency
Chinese Medical Equipment Journal 2009;30(7):114-115
The development history, the features and laws of guaranteeing medical supplies under emergency situation are introduced briefly. The allocation of resources, the key factors in management and the technique supply are described. By looking at the trend and the future work on how to guarantee medical supplies in the state of emergency, some conclusions can be made: guaranteeing medieal supplies in the state of emergency is a whole new field. Only when the experience is accumulated, and when the eoneepts and techniques from foreign countries are learned, the supplies for clinical and first aid to be delivered safely and in time can be guaranteed. Thus, the number of lives saved will be maximized.
3.Knowledge Retention Level among Pre-School Teachers in Conducting Pre-School Children Vision Screening
Malaysian Journal of Health Sciences 2019;17(Special Issue):149-156
Certain public service pre-school teachers have been trained as vision screeners of children. However, there are no studies that assessed the knowledge and skills retention of these screeners. This study determines the level of knowledge retention among pre-school teachers who have been trained to perform vision screening on children. In 2013, 180 KEMAS pre-school teachers were recruited in a vision screening training which included both theory and practical sessions. Teachers were assessed through a theory test which comprised of 15 questions, firstly a category on the preparations needed for vision screening and secondly on the implementation of vision screening. They were then asked to conduct pre-school vision screening annually at their working premises. In 2016, 136 teachers who had been involved in the earlier program were recruited as subjects in this study. All these subjects answered the same set of theory test questions used in 2013. The Student’s t-test result indicated that the mean theory test scores obtained by the pre-school teachers in 2013 (84.3 ± 7.8) differed significantly with the mean scores obtained in 2016 (67.5 ± 11.3) (p < 0.001). The mean scores in 2013 for questions in the first and second categories were 4.5 and 4.4, decreasing to 4.2 and 3.7 in 2016. The knowledge level of pre-school teachers thus decreased with time and this effect was found significant after 3 years. There is therefore a need to conduct re-certification training, so that the screening conducted by these pre-school teachers remains effective and in accordance with established standards.
4.Improvement Effect of Eucalyptol Enteric Soft Capsule on Lipopolysaccharide-induced Acute Lung Injury in Mice
China Pharmacy 2017;28(19):2655-2658
OBJECTIVE:To investigate the improvement effect of Eucalyptol enteric soft capsule on mice with lipopolysaccha-ride(LPS)-induced acute lung injury(ALI). METHODS:60 mice were randomly divided into blank control group,model control group,Eucalyptol enteric soft capsule low-dose,medium-dose,high-dose groups(100,300,900 mg/kg),12 in each group. Mice in administration groups were intragastrically given relevant medicines,mice in blank control group and model control group were intragastrically given equal volume of normal saline(0.1 mL/10 g). After 2 h of administration,except for the blank control group, ALI was induced in other groups by atomized LPS. After 6 h of modeling,the mice were sacrificed,alveolar lavage fluid(BALF) and lung tissue were taken. Morphological changes of lung tissue were observed under microscope;number of total cells,neutro-phils in BALF were calculated by blood cell count plate and staining by wright-giemsa respectively. Total protein concentration in BALF supernatant was detected by BCA method;TNF-α,IL-6 contents in BALF supernatant were determined by enzyme-linked immunosorbent assay. RESULTS:Compared with blank control group,lung tissue of mice in model control group showed obvious pathological damage and severe pulmonary edema;number of total cells,neutrophils in BALF,total protein concentration and TNF-α,IL-6 contents in BALF supernatant were significantly increased(P<0.01). Compared with model control group,pathologi-cal damage in lung tissue of mice was obviously improved in Eucalyptol enteric soft capsule high-dose group,number of total cells,neutrophils in BALF,total protein concentration and TNF-α,IL-6 contents in BALF supernatant were significantly decreased (P<0.05);and there were no significant differences in other groups (P>0.05). CONCLUSIONS:High-dose Eucalyptol enteric soft capsule can obviously improve LPS-induced ALI of mice.
5.Current status and future about maintenance treatment of advanced colorectal cancer
Cancer Research and Clinic 2011;23(8):567-569
Through PubMed, CNKI and other databases to retrieve original documents about the maintenance treatment of advanced colorectal cancer, collect and analyzed research theory and progress in the maintenance treatment of advanced colorectal cancer. The clinical efficacy of maintenance therapy are evaluated and the patient's disease-free survival and quality of life are observed. The Result shows that the maintenance treatment can improve disease-free survival of advanced colorectal cancer patients, and the toxicity of maintenance treatment can still be tolerated. So the maintenance treatment of advanced colorectal cancer has better clinical efficacy, it is worth to study in the future.
6.Application value of CT perfusion imaging with acetazolamide challenge test in the diagnosis of chronic cerebral insufficiency
Chinese Journal of Geriatrics 2014;33(4):351-354
Objective To explore the CT perfusion imaging with acetazolamide (ACZ) challenge test in the diagnosis of chronic cerebral insufficiency.Methods 100 patients undergoing health examination in our hospital from Aug 2009 to Feb 2011 were chosen,52 patients diagnosed as chronic cerebral insufficiency were defined as the case group,and the remaining 48 cases of healthy elderly people were defined as the control group.The brain CT perfusion imaging with acetazolamide challenge test,and the cerebral blood flow (CBF),cerebral blood volume (CBV),mean transit time (MTT) and time to peak (TTP) in anterior cerebral artery (ACA),middle cerebral artery (MCA)cortical branch supply area,MCA deep perforator region,posterior cerebral artery (PCA) and pons part blood supply area were examined in the elderly people of two groups.Results CBV and CBF values in ACA,MCA cortical branch supplyarea,MCA deep perforator region,PCA and pons part blood supply area after ACZ stimulation were significantly lower in case group than the control group (t=3.57,3.39,9.34,11.04,4.21,5.99,9.91,11.10,6.66,9.97,P<0.01 or 0.001),while MTT and TTP values were significantly higher in case group than in the control group (t =7.21,6.94,16.53,4.82,11.67,6.46,6.11,6.71,6.87,4.82,all P< 0.001),CBV and CBF values in the control group were significantly higher after ACZ excitation than before the challenge (t=6.44,6.86,9.72,10.99,7.03,6.33,12.48,14.82,8.98,12.03,all P<0.001),and the MTT and TTP values in the control group were significantly lower after ACZ excitation than before the challenge (t=7.98,5.77,17.29,8.28,9.74,7.01,7.52,6.32,6.01,5.54,all P<0.001).Conclusions CT perfusion imaging with acetazolamide challenge test can increase the detection rate of chronic cerebral insufficiency with better clinical significance,and is worthy of promotion.
7.Domestic Situation and Future Perspective of Isolated Dissection of the Superior Mesenteric Artery
Chinese Journal of Minimally Invasive Surgery 2016;16(10):865-869
[Summary] The isolated dissection of the superior mesenteric artery ( IDSMA) was once considered to be a rare disease .In recent years , a growing number of cases of IDSMA have been reported , especially by Chinese authors , because of the increasing use of contrast-enhanced computed tomography scans .To understand the real domestic status of IDSMA , the Chinese-language literatures were searched, and the clinical characteristics and treatment of IDSMA were analyzed .
8.Clinical applications of optical coherence tomography angiography
Chinese Journal of Ocular Fundus Diseases 2017;33(1):3-6
Optic coherence tomography (OCT) is one of the most rapid developing technologies in ophthalmology. OCT angiography (OCTA) has been made possible by the development of even faster scanning and sampling techniques, which is the next milestone after stratus OCT and spectral domain OCT. Without the need of injection of the contrast agent, OCTA is capable of providing a three-dimensional reconstruction of the perfused microvasculature within the retina and choroid by detecting the motion of scattering particles such as erythrocytes within sequential OCT cross-sectional scans performed repeatedly at the same location of the eye with different analysis algorithms. Comparing to fundus fluorescein angiography and indocyanine green angiography, with improved OCT technology and understanding, OCTA has showed certain advantages to diagnose retinal and choroidal diseases, especially macular vascular diseases. It is important to establish the contributions that OCTA can make to diagnosing, managing and understanding of ocular fundus diseases.
9.Bibliometric analysis of core periodicals of military medicine based on SCI
Military Medical Sciences 2016;40(12):994-998
Objective To analyze the literature of two core periodicals ,Military Medicine of the USA and Journal of the Royal Army Medical Corps of the UK,in order to highlight some important authors ,research institutes and some hot spots in the field of military medicine .Methods Citespace and Excel were used to analyze the data of authors institutes , keywords and citation frequency of the collected records .Results and Conclusion The core authors and critical research institutes are mainly from the USA and UK .America is absolutely taking the leading position in research on military medicine that focuses on injury risk factors , trauma and care , mental health , veteran affairs , military epidemiology and prevention .The results are of referential value for researchers and research administrators to find out about the main core authors ,research institutes and hot spots in military medicine .
10.Function of purinergic receptorsin communication between neurons and glial cells
Chinese Pharmacological Bulletin 2017;33(4):450-454
The function of the nervous system is largely determined by the communication between neurons and glial cells.The interaction of complex signaling pathways between neurons and glial cells involves in a variety of signaling molecules.Purines and the purinergic receptors play a crucial role in the process of the interaction.For a long time, the study on the central nervous system is mainly focused on neurons, while glial cells are mainly used as support cells or in response to brain injury to provide a guiding role.The latest research shows that glial cells play an important role in the occurrence and development of nervous system diseases.We will summarize the function of purinergic receptors in the interaction of neurons and glial cells and in neurological diseases.