[Objective]To summarize Doctor Xuan Guiqi's experience in the treatment of childhood asthma and the idea of improving the curative efficacy. [Methods]By learning from Doctor Xuan and clearing up medical cases, the author finishes the summary on doctor Xuan's clinical experience on child-hood asthma based on the syndrome differentiation and clinical medication.[Results]The childhood asthma is divided into acute and chronic, the former is divided into cold asthma, heat asthma and wind-phlegm types. At the same time, we strengthen pertinence treatment of clearing heat and removing toxi-city, Qi spasmolytics, dispel ing wind and desensitization, activating blood and eliminating stasis, promoting Qi and regulating middle-jiao and relieving dyspepsia.[Conclusions] Doctor Xuan Guiqi's experience in the diagnosis and treatment of childhood asthma can significantly improve the clinical efficacy , and it is meaningful to clinic.

The concept of nutraceutical food was introduced firstly in United State in 1989 by Stephen Defelice, the founder of the Foundation for Innovation in Medicine. It is defined as a product that considered as a food or a part of food, provided medical or health benefits, including disease prevention and treatment”. The health sector should review and re-evaluate the importance and potential of the nutraceutical food market and plan the development strategy for this novel avenue. The unique definition of nutraceutical product is needed. The Ministry of Health should direct the management of these products as medications rather than foods and the regulations of registration, labeling and take testing samples should be available
Food ; Dietary Supplements ; Comment [Publication Type

Allergic reaction to drugs (ARTDs) occurs frequently in adults who are usually suffered from many diseases and who require multiple courses of medications. Investigative result showed that: The incidence of ARTDs in elderly is 6.74%, this incidence in patients of Asthma group is 14.7%. The main cutaneous manifestations of ARTDs in elderly patients included: urticaria and erythematous rashes (42.5%), erythrodermie (14.9%), erythematic multiform (21.3%), fixed drug eruptions (12.7%), vesiculobullous eruptions (6.4%).
Drug Hypersensitivity ; aged

The importance of hemodynamic monitoring is reflected in the correct interpretation of the monitoring results and taking simultaneously the appropriate treatment strategy according to the correct interpretation of the results.The essence of the shock is body tissue hypoperfusion,whtich result in tissue hypoxia and organ dysfunction.The essence of the hemodynamic imbalance is the imbalance of oxygen supply and oxygen consumption.Therefore,the end point of the fluid resuscitation for shock is now increasing emphasis on monitoring mixed/central venous oxygen saturation and the concentration of blood lactate,the rate of lactate clearance.

The children with septic shock could not be presented in hospitals with PICU facilities first.Furthermore,from a pathophysiologic perspective paediatric shock does not resemble adult septic shock.This suggests that every physician that could be faced with these children needs to understand how to recognize paediattic shock and have basic knowledge of the principles of primary management.

The guide of fluid resuscitation for septic shock is universal instructional.However,different individuals present different pathophysiologic characteristics.The clinicians should pay attention to the specific children when fluid resuscitation was performed.In this article,we discussed the specificity of fluid resuscitation for septic shock.

Because bronchoscopy and CT technology development,the number of confirmed cases of children with airway stenosis have increased every year,but clinical management of pediatric airway constriction is a very thorny issue.This article described the application principles,indications and methods of thermal cauterization,cryotherapy,balloon dilatation airway-plasty and airway stent in airway stenosis.

The development history, the features and laws of guaranteeing medical supplies under emergency situation are introduced briefly. The allocation of resources, the key factors in management and the technique supply are described. By looking at the trend and the future work on how to guarantee medical supplies in the state of emergency, some conclusions can be made: guaranteeing medieal supplies in the state of emergency is a whole new field. Only when the experience is accumulated, and when the eoneepts and techniques from foreign countries are learned, the supplies for clinical and first aid to be delivered safely and in time can be guaranteed. Thus, the number of lives saved will be maximized.

The mechanism of drug resistance of refractory epilepsy has remained unclear.In recent years,studies have shown that the multi-drug resistance associated protein(MRP) is related with refractory epilepsy.The mechanism responsible for the drug resistance may have something to do with the higher expression of MRP1 mRNA in brain tissues of refractory epilepsy patients.Through the use of drugs in cells to cells from the pump,it can reduce the drug concentration in brain and make the creation bears the medicine and inhibitors specific for MRP,which can significantly improve the effect of some antiepileptic drugs.Thus,further studies may provide new ways for the treatment of refractory epilepsy and find targets for new antiepileptic drugs.

Sepsis,the systemic inflammatory response syndrome(SIRS)induced by infection,is the first cause of death of patients in intensive care unit. Early diagnosis of sepsis with the actions of corresponding treatment can improve the prognosis of sepsis.It is an appropriate way to achieve early diagnosis of sepsis that using proteomics methods to detect unknown proteins during early stage of sepsis,in which we search for new protein biomarkers.