To predict the potential therapeutic efficacy of combination of antibiotics, methods have been developed to quantitative their effects on bacterial growth in vitro. Two distinct different methods are used. The first methods for evaluating drug combinations involve quantitation on their rate of bactericidal action. The second employs serial twofold dilution of antibiotics in broth in osculated with a standard number of the test microorganism in a checkerboard fashion, so that antibiotic concentration in different proportion can be tested simultaneously. Laboratory trials have carried out on antimicrobe resistant S. anreus. We found that gentamicine combined penicillin or gentamycine combined cephalothin in more rapidly bactericidal effect than either drug alone, the result is termed synergism. On the contrary, antagonism in said to occur with penicillin combined chloramphenicol.
Anti-Bacterial Agents ; Staphylococcus

Background: Many studies showed that food safety handling practice is limited in many subjects, especially employees of public canteens and street restaurants. Objective: Strengthen the knowledge on food safety handling practices for staffs of canteens surrounding Hanoi medical university. Subject and Method: An IEC intervention was carried out from December, 2006 to June, 2007 in order to improve food safety handling practices among the personnel of 7 canteens surrounding Hanoi Medical University. The sample size of 34 employees was collected and interviewed with regards to their handing practice on food by using a checklist and a structured questionnaire. The utensils hygiene was assessed by a quick biochemical test. Result and Conclusion: There were significant changes in food handling practices among staffs after the intervention which proved by the regular medical examination, the improvement in hand-washing habits; dish cleaning; ways of picking up cooked-foods; however, almost all of the observed canteens did not follow the rules of food sources management and daily storage sample of foods. \r\n', u'\r\n', u'
IEC intervention ; Food safety

Objectives: The prevalence of posttraumatic stress disorder (PTSD) has increased, particularly among individuals who have recovered from coronavirus disease 2019 (COVID-19) infection. Health literacy is considered a “social vaccine” that helps people respond effectively to the pandemic. We aimed to investigate the association between long COVID-19 and PTSD, and to examine the modifying role of health literacy in this association. Methods: A cross-sectional study was conducted at 18 hospitals and health centers in Vietnamfrom December 2021 to October 2022. We recruited 4,463 individuals who had recovered from COVID-19 infection for at least 4 weeks. Participants provided information about their sociodemographics, clinical parameters, health-related behaviors, health literacy (usingthe 12-item short-form health literacy scale), long COVID-19 symptoms and PTSD (Impact Event Scale-Revised score of 33 or higher). Logistic regression models were used to examine associations and interactions. Results: Out of the study sample, 55.9% had long COVID-19 symptoms, and 49.6% had PTSD.Individuals with long COVID-19 symptoms had a higher likelihood of PTSD (odds ratio [OR], 1.86; 95% confidence interval [CI], 1.63–2.12; p < 0.001). Higher health literacy was associated with a lower likelihood of PTSD (OR, 0.98; 95% CI, 0.97–0.99; p = 0.001). Compared to those without long COVID-19 symptoms and the lowest health literacy score, those with long COVID-19 symptoms and a 1-point health literacy increment had a 3% lower likelihood of PTSD (OR, 0.97; 95% CI, 0.96–0.99; p = 0.001). Conclusion Health literacy was found to be a protective factor against PTSD and modified the negative impact of long COVID-19 symptoms on PTSD.

As part of our continued study on the chemical constituents of Willughbeia edulis stems, a new dimeric lignan named edulignan (1) was isolated from its EtOAc-soluble extract. Based on NMR spectroscopic interpretation, the planar structure of 1 has been suggested to have two 2-substituted 4-chromanone subunits with different stereochemical configurations. In addition, the MS/MS analysis of the products obtained by acidcatalyzed hydrolysis of 1 was supportive of its structure. Unfornatually, the new compound 1 did not show α-glucosidase inhibitory activity with an IC 50 value > 250 μM.