1.Traffic accident and cerebrocranial injuries
Journal of Practical Medicine 2002;429(8):53-55
We conducted a retrospective study on the medical records of patients with traffic accidents in Viet Duc Hospital. Results showed that the mortality rate and traffic accident were increasingly with development of socioeconomy. The mortality rate related with traffic accident was the same as this in Egypt. Most of them were men and ages of 24-45. Motorbike was most frequent cause of traffic accident. The rate of helmet using was low.
Accidents, Traffic
;
Wounds and Injuries
2.The relation between factors prior to cerebrocranial injuries and rehabitation
Journal of Practical Medicine 2002;429(8):45-46
We conducted a study on 45 patients treated in the rehabilitation facilities after 2 years of cerebrocranial injuries due to weapon, traffic accident, with average ages of 33. Results have shown that there was close relation between the psychological condition and drug addiction before cerebrocranial injuries. The psychological condition and drug addiction related closely with the posttraumatic unemployment and dependent life. There was a relation between supportive level of society and patient's and their family's behaviors.
Rehabilitation
;
Wounds and Injuries
3.Cognitive impairment in children with sleep-disordered breathing
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(10):957-960
Objective To review the characteristics,mechanism,the brain structural and functional changes of cognitive impairment induced by sleep-disordered breathing in children.Methods The retrieve time was from 2002 to 2014 and the retrieve databases were the US.national library of medicine and Weipu Chinese journal databases.Search word included sleep disorders breathing, cognitive, sleep apnea syndrome, neurobehavioralmanifestations,image,sleep deprivation.Results 52 English literature and 1 Chinese literature were accepted.Most literatures were clinical trial, comparative study, multicenter study, randomized controlled trial, controlled clinical trial.Conclusion The study in the cognitive impairment and characteristics change of the brain function and structure in children with SDB is not enough.Most cognitive assessments are completed by scale.How to diagnosis early,more objectively assess cognitive, study molecular mechanisms, study function change and positioning of brain function need more research in clinical.
4.Pre- evaluation of Effect of Litalin in Children with Attention Deficit/Hyperactivity Disorder by P300
wei, SHENG ; yu-xia, YANG ; xuan, DONG
Journal of Applied Clinical Pediatrics 2004;0(11):-
Objective To investigate the change of P300 of the attention - deficit/hyperactivity disorder children before and after they took litalin, according to this objective subject to guide the clinical treatment of ADHD children. Methods Using the looking se-ducible electricity stimulates 22 ADHD children, and check the change of latency and the rate of the wave before and after they took litalin. Results After ADHD children took litalin, their latency of P300 has decreased clearly, and the amplitude had no change. Conclusion The changes of P300 latency in ADHD children after they took litalin can be adopted as the guidelines of clinical treatment for the ADHD children.
5.Laparoscopic procurement model for left lobe living donor liver transplantation
Xuan ZHANG ; Hongguang WANG ; Jiahong DONG
Chinese Journal of Organ Transplantation 2010;31(9):562-564
Objective To assess the feasibility of laparoscopic hepatic lobe procurement for living donor liver transplantation. Methods The technique included pneumoperitoneum with CO2,ports placement, porta hepatis dissection, laparoscopic ultrasound mapping, mobilization of the liver,and transection of the parenchyma into right and left lobes. The vascular structures were stapled and sectioned just prior to removal of the specimen. Results Hepatic lobectomies were successfully performed laparoscopically in 9 adult pigs. One pig was dead due to bleeding in IVC and following gas embolism during the parenchymal transection. The operative time was 208±25 min. The duration of warm ischemia was 8 ± 2. 3 min. The blood loss was 313 ± 75 mL. The vascular and biliary structures were preserved to allow for subsequent transplantation. Conclusion Laparoscopic living donor procurement for liver transplantation in a porcine model is safe and feasible.
6.Lower extremity deep venous insufficiency and Cockett syndrome.
Guoxiang DONG ; Xuan LI ; Jun ZHAO
Chinese Journal of Practical Surgery 2001;21(5):276-277
Objective This study was To investigate the incidence rate of Cockett syndrome and relationship between Cockett syndrome and varicose veins and deep venous incompetence of the left lower extremities.Methods 73 patients(100 legs) with varicose veins of the lower extremities were investigated by descending deep venography and iliography preoperatively.Results There were 35(47.9%) cases with abnormalities of the left common iliac vein (ALCIV)in all the cases.There were 31 cases with this conditions in the patients with varicose veins of the left or both lower extremity.While in the patients with varicose veins of the only right lower extremity,there were only 4 cases with ALCIV.In contrast,there was a significant difference between groups(χ2=9.8641,P=0.0017).In the patients with ALCIV,14 cases with Ⅲ or Ⅳ grade of deep venous incomptence were found, and only 6 cases with deep venous incompetence in the patients without ALCIV.There was a significant difference(χ2=5.3688,P=0.0205).Conclusion Cockett's syndrome frequently occurs in varicose veins of the left lower extremity.There is a relationship between them.Cockett's syndrome might be one of the causes for the deep venous incompetence of the left leg.
7.Clinical application of transcatheter arterial thermo-chemotherapy and thermo-lipiodol embolization in treatment of hepatocellular carcinoma
Xuan WANG ; Xiaofei CHEN ; Weihua DONG
Journal of Interventional Radiology 2001;0(06):-
Objective To evaluate the clinical efficacy of thermo-chemotherapy and thermo-lipiodol embolization intreatment of primary hepatocellular carcinoma(PHC).Methods One hundred and sixteen cases of PHC were divided into three groups.Group A(38 cases)was treated with normal temperature chemotherapy and normal temperature lipiodol,Group B(40 cases)with thermo-chemotherapy and normal temperature lipiodol and group C(38 cases)with thermo-chemotherapy and thermo-lipiodol.Group B and group C were called the thermotherapy group.Results In the thermotherapy groups,the rates of tumor size reduction were significantly greater than those in the normal group.There were no significant different in the hepatic function tests among the three groups.The 6-,12-,18-,and 24-month survival rates of the normal group and thermotherapy groups were 97%,58%,39% and 18%,versus 99%,79%,57% and 36%,respectively.No significant differences were found in the rates of reduction of tumor size and survival rates between group B and group C.Conclusion Thermo-chemotherapy and thermo-embolization possess significant effect on PHC but without conspicuous damage to liver function.
8.Relative study of event-related potentials elicited by calculating and number recognizing
Jinzhong HUANG ; Xuan DONG ; Heqing ZHAO
Journal of Clinical Neurology 1997;0(06):-
Objective To investigate the relation of event-related potentials (ERPs), which are evoked by calculating and number recognizing stimuli.Methods We examined 26 healthy undergraduate students with double-digit (Arabic numbers) and single-digit modify a prescription problems. While the stimulus information was presented, electroencephalogram (EEG) was recorded simultaneously. ERPs were extracted from EEG data, and then the feature and source of ERPs were analyzed.Results Both calculation and number recognizing induced positive and negative components of ERPs with similar wave form and different latency. The latency of ERPs was conspicuously shorter elicited by number recognizing than by calculating. Grand mean mapping showed the highest amplitudes of ERPs were presented in parietal lobe elicited both by calculating and number recognizing.Conclusion The processing of calculating is more complicated than number recognizing. Calculating and number recognizing may have different electrophysiological background, and they belong to diverse processing course in the brain. Parietal lobe is the functional domains of them.
9.Role of the coagulation and fibrinolysis in acute lung injury
Yanqin DONG ; Jian LI ; Xuan ZHANG
Chinese Journal of Pathophysiology 1989;0(05):-
Acute lung injury(ALI) and acute respiratory distress syndrome(ARDS) are common,life-threatening causes of acute respiratory failure that arise from a variety of local and systemic insults.The pathogenesis of ALI/ARDS is complicated and not yet completely interpreted today.The role of altered coagulation and fibrinolysis in the pathogenesis of ALI/ARDS has been investigated.This review will summarize the current understanding of coagulation and fibrinolysis in human ALI/ARDS with emphasis on pathways that could be potential therapeutic targets.These pathways include the tissue factor pathway,the protein C pathway and modulation of fibrinolysis via plasminogen activator inhibitor-1.
10. Antiaddictive indole alkaloids in Ervatamia yunnanensis and their bioactivity
Academic Journal of Second Military Medical University 2006;27(1):92-96
Objective: To investigate the constituents of indole alkaloids in Ervatamia yunnanensis and their antiaddictive bioactivities. Methods: The preliminary alkaloids (TEYA) were extracted by 95 % EtOH from the stems of Ervatamia yunnanensis. TEYA was then purified by silica gel and Sephadex LH20 column chromatography repeatedly and its structure was identified with spectral analysis. The antiaddictive effects of these indole alkaloids were evaluated by Conditioned Place Preference (CPP) experiments. Results: Nine indole alkaloids were obtained and identified as: coronaridine (1) , voacangine (2), 3-R-ethoxycoronaridine (3), 3-S-ethoxycoronaridine (4), 19-epi-heyneanine (5), heyneanine (6), 19-epi-voacristine (7), coronaridine hydroxyindolenine (8) and 12-methoxyl-voaphylline (9). Among them voacangine (2) and 19-epi-voacristine (7) were effective in prevention and treatment of addiction induced by morphine in rats (n=8). Conclusion: Compounds 3, 4, 8, and 9 have been isolated from Ervatamia yunnanensis for the first time and coronaridine-type indole alkaloids are the main antiaddictive constituents of E. yunnanensis.