Objective To increase diagnose and cure capability on the emotional disturbance children shown on somatization in pediatrics of general hospital.Methods 100 cases of emotional disturbances in children were selected to take somatic manifestations as to mainly express in pediatrics out-patient service in my hospital and was made by the professional psychiatrist to visit patients at home to cure a project,and evaluate curative effect.Results From pediatrics out-patient service transfer to mental out-patient service to seek medical advice partition time:12 cases were 1～3 months,21 cases were 6 months,67 cases were more than 6 months.67% patients saw a doctor after 6 months illness to make a diagnosis and treatment.In addition to environment stimulate motion obstacle of ourbreak factor had something to do with suffering from the emotional factor.Somatic manifestations were symptoms of cardiovascular system,neurological system,gastrointestinal system,urinary system etc:they were cured by psychotherapy and medicine therapy,95% children could recover from their illness.Conclusion Clinical pediatricians in general hospital should pay attention to the emotional disturbance in children taken somatic manifestations as mainly expression,raise diagnosis and treatment level.

OBJECTIVE To further strengthen the link monitor of hospital infection management of MDRO,prevent and control the occurrence and spread of MDRO in the hospital and ensure medical safety.METHODS The occurrence of MDRO,and the sterilization were monitored to guarantee the medical care personnel not infected with MDRO,Asepsis process during treatment and nursing,was supervised to cut off the weak link of MDRO spread,carry out standard prevention sense throughout,normalize the use of antibiotics,and fulfill the education of MDRO infection knowledge.RESULTS Through hospital infection management of MDRO,it got the effect of early prevention,early diagnosis and early control,reduced the infection rate of MDRO,prevented the occurrence and spread of MDRO in the hospital and ensure the medical safety.CONCLUSIONS Well done in the link of hospital infection management of MDRO is one of essential contents to evaluate the hospital infection management level,and improve medical care quality and ensure medical safety.

Objective To explore the clinical application value of minimally invasive endoscopic visual artificial abortion operation system in Painless abortion. Methods 250 cases early pregnant women who underwent minimally invasive endoscopic visual artificial abortion operation system implementation of Painless abortion from June 2015 to December 2015 were selected as visual painless abortion group,while Two hundred and fifty cases early pregnant women who demanded routine painless abortion during the same period were selected as routine painless abortion group. The operation time, the amount bleeding, the villus integrity, the number of cases of once again clear palace operation , the vaginal bleeding time after operation, and the first menstruation recovery time after operation among the pregnant women in the two groups were analyzed. Results There was statistically significant difference in the operation time, amount bleeding, villus integrity, the number of cases of once again clear palace operation , vaginal bleeding time after operation, and the first menstruation recovery time after operation between the two groups ( P<0. 05) . The Observation index of the pregnant women in visual painless abortion group was Obviously superior of that in routine induced abortion group . Conclusion Minimally invasive endoscopic visual artificial abortion operation system implementation of Painless abortion is worthy to be popularized and applied in clinic.

Objective To study the preoperative nursing care in excision of adrenal tumor by using laparoscope. Methods 72 patients with adrenal tumor have undergone the excision of adrenal tumor by using laparoscope in our hospital. Preoperative nursing included mental care, cardiac and pulmonary function assessement, pharmacotherapy, gastrointestinal and skin preparation. Postoperative monitoring the condition of all the patients, and given oxygen uptake to prevent hypercarbonemia. All the patients were encouraged to do functional recovery early and were guided to diet properly. Results All patients were successful obtained the excision of adrenal tumor by using laparoscope except two were reversed to open surgery. The patients could take food and leave bed in the first post-operative day. The mean post-operative stay was 6 days. Hydrothorax occurred in 2 cases and fat liquidation and wound infection occurred in 2 cases. There were no major complications such as hemorrhage and hypercarbonemia occurred. Conclusion The excision of adrenal tumor by using laparoscope is safe and reliable. Sufficient preoperative preparation, careful post-operative monitoring and timely using counter-measure are the key points in nursing care.

OBJECTIVE: To review the pathological and clinical features and treatment of sinonasal malignant melanoma. METHOD: A retrospective analysis of 23 cases of sinonasal malignant melanoma. All the patients were conformed by histopathology, the most common symptoms were nasal obstruction and epistexis. Eight cases were treated with surgery, 8 with surgery and radiotherapy, 5 with surgery and chemotherapy, 2 with surgery and ra- diotherapy plus chemotherapy. RESULT: Twenty patients were followed up, the survival rates of 3 and 5 years were 50% (10/20) and 35% (7/20), respectively. CONCLUSION Sinonasal malignant melanoma has an aggressive behavior and easy recurrence and poor prognosis. Early diagnosis and reasonable treatment can increase the survival rate of the disease.
Humans ; Melanoma ; mortality ; pathology ; therapy ; Nasal Obstruction ; Neoplasm Recurrence, Local ; Nose Neoplasms ; mortality ; pathology ; therapy ; Paraganglioma ; Paranasal Sinus Neoplasms ; mortality ; pathology ; therapy ; Retrospective Studies ; Survival Rate

Causal inference research is a causal test designed to assess the impact of exposures on outcomes.Both experimental and observational studies can be used to examine causal associations between exposure factors and outcomes. Experimental studies are sometimes limited by factors such as ethics or experimental conditions. Observational studies account for a large proportion in clinical studies, but the effectiveness and research value of observational studies will be affected if the design of observational studies is not rigorous and the confounding factors are not well controlled.The Guidelines for controlling confounding factors and reporting results in causal inference studie formulated by a special group of 47 editors from 35 journals from all over the world provide good guidance to researchers. This article interprets the guidelines and hopes to provide help for clinical researchers.

Objective To explore the neuroprotective effect of honokiol against Parkinson's disease(PD)in mouse model,and investigate the possible mechanism involved.Methods 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)was injected into abdominal cavity of mouse to establish the PD model.Sixty C57BL/6 male mice were randomly allocated into five groups:control group,MPTP model group,amantadine group(positive control,40mg/kg),honokiol group A(10mg/kg)and honokiol group B(30mg/kg).Spontaneous movement test was used to measure the activity frequency of each mouse in 5 minutes.The technique of high performance liquid chromatography-electrochemistry was utilized to detect the changes of dopamine(DA)contents in mouse striatum.Results a)Since the involuntary movement appeared,such as trunk trembling,piloerection,tail extending and movement reduction,the PD model was regarded as having been reproduced successfully.b)The spontaneous movement frequency in 5 minutes of the mice in MPTP model group(102?7)was lower than that in the control group(583?11,P

1.78 mmol/L,intact parothyroid(iPTH)2.37 mmol/L,calcium dose was 1 000 mg/d;if serum Ca~ 2+ was0.05].After low-calcium dialysis(1.25 mmol/L Ca~ 2+ dialysate)for 6 months:the serum Ca~ 2+ level had no change[(2.37?0.26)mmol/L to (2.41?0.24)mmol/L];the serum P level had decreased significantly from[(2.60?0.47)mmol/L to (2.29?0.58)mmol/L];the iPTH had increased significantly from[(130.7?84.6)pg?mL~ -1 to (169.2?105.8)pg?mL~ -1 ,P

Objective To develop a method for the determination to organochlorine pesticides by gas chromatography-mass spectra-mass spectra.Methods The temperature of inlet was 250 ℃,the injection volume was 1 ?l,without split injection.The temperature of EI source was 300 ℃,the ionization energy was 70 eV,solvent delay time was 3.75 min,transfer line temperature was 280 ℃.181,235,246(m/z)were selected as parent ion,and 145,165,176(m/z)were sub ion.Results In the range of 0-50 ?g/L,every component had a good linearity,r≥0.99,the limit of detection≤0.01 ?g/L.Its average rate of recovery was in the range of 86.1%-101.8%,and the relative standard deviations(RSDs) were between 4.41%-8.07%.Conclusion Gas chromatography-mass spectra-mass spectra is more precise for the qualitative and quantitative determination of trace organochlorine pesticides residues in drinking water.

The cell-impedance substrate sensor,which is mainly used to detect the shapes and function ofcells and other micro.organism.is a novel tool based on the technique of BIOMEMS to study the cellular physiologyand clinical Dharmasology.It has drawn attention from both domestic and international scholars as well as compa nies in recent years for its advantages such as innovative design and long-term non-invasive monitoring.This paperintroduces the interfacial model of cell-sensor in detail and gives a sketch of the recent international researchprogress.Then the novel interdigitated array,which was designed in our group recently,is introduced.The fore ground of development is discussed in the end.