Objective] To study the effect of kneading pull-turning methods together with the family care and treatment on children congenital muscular torticollis. [Methods] 60 cases of congenital muscular torticollis were randomly divided into kneading pull-turning methods together with the family care group(treatment group) and conventional massage group(control group) with symptoms, signs and evaluation of clinical curative effect between groups of children. [Results] The treatment group cure rate was 76.67%, control group cure rate was 43.33%, the curative effect of treatment group was obviously better than the control group(P<0.05). [Conclusion] Kneading pull-turning methods together with the family care in treatment of children with congenital muscular torticollis has the characteristics of high cure rate which is conducive to recovery of affected children.

Objective To study current situation of creativity among medical students and its influential factors, and to explore structural equation model about influential factors of creativity. Methods The sample was randomly chosen by using cluster-based sampling method, 413 students in medical university were tested by Williams creativity scale and the influential factors of creativity questionnaire. Results Among the medical student's creativity characters, the most extrusive character was challenge(2.35±0.26), the more important were curiosity(2.29±0.28) and risk-taking(2.21±0.27), and imagination(2.04±0.33) was less important. The structural equation model of influential factors of creativity implied that mental health was the most important factor about improving medical student creativity and by changing study style could promote creativity of medical students. Conclusion By establishing structural equation model, we not only study the influential factors of creativity in realistic view, but also master important extent of each influential factors theoretically.

Five natriuretic peptides (NP) have been identified: A-type, B-type, C-type, D-type and V-type. All of them have ringed-structures. The actions of the natriuretic peptides are modulated through their cognate receptors, which are named as NPR-A,NPR-B and NPR-C. The receptors are involved in the cGMP-dependent signaling cascades,which take part in many different physiological regulation, such as diureses,vasodilatation, depressing blood pressure, improving immunity, promoting development of bone, regulating nerve system and so on. At present, ANP and BNP have become a marker in diagnostic some cardiovascular diseases.

Ischemia-reperfusion injury is common in clinical treatment.Free radical induced oxidative stress plays an important role in this process.Recently,it is reported that hydrogen can selectively scavenging hydroxyl radical in rodents,thus alleviate ischemia-reperfusion injury.Since hydrogen is easy to penetrate the barriers in the body with littie adverse effects,it is hopefully to become a promising agent against ischemia-reperfusion injury in the future.

Objective To investigate the clinical efficacy of ultrasonic scaling combined with the vinegar-for treatment the patients with dental calculus.Methods 120 patients with dental calculus dental were randomly divided into two groups.Control group used ultrasonic scaling treatment,observation group was given ultrasonic scaling combined with the vinegar treatment.Results The clinical cure rate of the observation group was 96.67％ (58/60),the incidence rate of complications was 6.67％ (4/60).The clinical cure rate of the control group was 68.33％ (41/ 60),the incidence rate of complications was 21.67％ (13/60).There were statistically significant differences between the two groups about the cure rate and the incidence of complications (x2 =14.37,3.61,P ＜ 0.05).After treatment,periodontal pocket depth of the observation group was significantly lower than that of the control group (P ＜ 0.05).Sulcular fluid volume of the observation group was significantly lower than that of the control group (P ＜ 0.05).The difference of oral sample results of bacterial culture after treatment was statistically significant between the two groups (P ＜ 0.05).Conclusion The clinical effect of ultrasonic scaling combined with the vinegar in treatment patients with dental calculus is certain,which is worthy of further promotion.

Cone-Beam Computed Tomography ; Humans

Objective To explore the therapeutic effect of Yupingfeng powder in secondary immunodeficiency caused by simple nephrotic syndrome(SNS) in children.Methods Seventy-eight cases of SNS patients were divided into 2 groups randomly.One was control group which were treated with immunosuppressant only.The other group was Yupingfeng powder group which were treated with both immunosuppressant and Yupingfeng powder.The morbidity of infection,the relapse rate of SNS,and serum immunoglobulin IgA and IgG and the T-lymphocytes subtype were detected before and after treatment in two groups.Results The morbidity with infection was 55.3% in Yupingfeng powder group,which shows a remarkable decrease compared with control group(85%).The relapse rate of SNS was 39.5% in Yupingfeng powder group which was much lower than that in control group(67.5%).The level of serum IgA and IgG before treatment were(3.88?1.22) g/L and(0.83?0.14) g/L and rose up to(10.06?1.89) g/L and(1.38?0.10) g/L after treatment in Yupingfeng powder group.Whereas the control group with(6.23?1.55) g/L and(0.85?0.13) g/L was remarkably lower than those in Yupingfeng powder group.CD4+,CD8+ and the ratio of CD4+/CD8+ were(37.91?3.89)%,(30.69?3.08)% and(1.24?0.49)% respectively before treatment.They rose up to(42.38?4.89)%,(26.01?2.20)% and(1.63?0.41)% respectively in Yupingfeng powder group,while those in control group were(39.87?3.91)%,(29.76?3.55)% and(1.34?0.24)% respectively after treatment.Conclusion It is feasible to treat the Yupingfeng powder to cure the of secondary immunodeficiency caused by SNS in children.

Ultraviolet (UV) is a kind of important environmental factor that can cause dermatitis,photoaging and skin cancerization.The UV-induced production of inflammatory factors by epidermal keratinocytes has been deemed an important molecular event in occurrence of the above diseases.Various receptors,intracellular signal transduction-related regulatory molecules and nuclear transcription factors are involved in UV-induced inflammatory responses in keratinocytes,which mainly include epidermal growth factor receptor,aryl hydrocarbon receptor,peroxisome proliferatoractivated receptor,protein kinase C family,protein kinase B,mitogen-activated protein kinase family,nuclear factor-κB and transcription factor activator protein-l,etc,and constitute a complex inflammatory signal transduction network.

A colorimetric self-indicating probe for glucose was constructed by self-assembly of MnO2 nanosheets (MnO2 NSs) and glucose oxidase(GOD) in this paper.Under the weak acidic medium,glucose oxidase specifically catalyzes glucose into gluconic acid and hydrogen peroxide.The by-product of hydrogen peroxide could efficiently dissolve the MnO2 nanosheets,resulting into a significant decrease of the characteristic absorbance at 374 nm assigned to MnO2 NSs.Furthermore,the absorbance difference was linearly proportional to the concentration of glucose ranging from 1 to 20 μmol/L The fitted curve could be used for quantification of glucose with a correlation coefficient of 0.990 1.And the detection limit as low as 0.1 μmol/L could be reached based on the definition of three times of the deviation of the blank signal (3σ) and there was negligible interference with other co-existing amino acids,anions,cations and protein,which indicated high sensitivity and selectivity of the hybrid probe.The construction strategy of designated probe is readily generalized in principle for detection of numerous analytes in view of reactive property of MnO2 and the diversity of enzymes.

ObjectiveTo investigate the association of γ-aminobutyric acid B2 receptor (GABABR2) gene polymorphism rs3750344 and bone mass (bone mass content, BMC, and bone mass density, BMD) in population of Chinese Hans lives in Jinan. Methods425 volunteers were recruited. BMC and BMD of all subjects were measured with dual energy X-ray absorptiometry (DXA). Genotyping of polymorphism rs3750344 was conducted using Taqman assays. ResultsBMD and BMC increased with the copy of the C allele of rs3750344 in whole body. ConclusionThe C allele of GABABR2 rs3750344 increases the levers of BMD and BMC in Chinese Han population.