4.Hepatitis B virus reactivation in hepatocellular carcinoma patients after microwave ablation
Wen LU ; Qingmin FAN ; Panpan WU ; Zhongqi XU ; Yun XU ; Guojun QIAN
Chinese Journal of Hepatobiliary Surgery 2015;21(5):297-300
Objective To investigate the risk factors of hepatitis B virus (HBV) reactivation after microwave ablation (MWA) and its prevention.Methods 72 patients who met the inclusion criteria were enrolled into the study.30 patients were in the control group and 42 patients in the prophylactic antivirus group.Results 8.3% (6/72) patients developed HBV reactivation.A high HBV DNA load and no prophylactic antivirus therapy were independent risk factors of viral reactivation.Conclusion Prophylactic antivirus therapy can prevent HBV reactivation.
5.Analysis of the applications of antibacterial agents to outpatients in primary hospitals in Hefei City of Anhui Province
Bingfa XU ; Kan QIN ; Shuanghu LI ; Han HAN ; Rui CHEN ; Yun XU ; Luyan FAN
Chinese Journal of Primary Medicine and Pharmacy 2014;(17):2570-2572
Objective To investigate the applications of antibacterial agents to outpatients in primary hos -pitals in Hefei City of Anhui Province,and to provide reference for rational use of antibacterial agents.Methods In 2011, fourty-five primary hospitals in Hefei City were selected randomly ,including urban community health service centers (Group A) and township hospitals(Group B),and thirty or fourty outpatient prescriptions were analyzed monthly . Results In Group A, the percentage and intensity of antimicrobial usage , the proportion of the combination and injectable formulation were ( 45.36 ±20.02 )%, ( 89.73 ±25.50 ) DDDs · ( 100 cases ) -1 · d-1 , 13.34%, 23.16%,respectively,and the data in Group B were (61.36 ±17.18)%,(108.46 ±32.27)DDDs· (100 cases) -1 · d-1,29.13%,46.39%,respectively,which the former were significantly lower than the latter.Conclusion In primary hospitals,the applications of antibacterial agents to outpatiants are not rataional ,including high percentages of usage and unreasonable selection of species ,and more supervision and training need to be given to the medical staff , especially in township hospitals .
6.Morphological characteristics of eyes of female Uygur youth: an anthropometric study
Chengliang ZHANG ; Dongwen SHI ; Yun GUO ; Shuping ZHU ; Yali FAN ; Youliang LI ; Guoming XU
Chinese Journal of Medical Aesthetics and Cosmetology 2015;21(1):1-4
Objective To study the morphological characteristics of eyes of female Uygur youth for providing the relevant data for eye aesthetic plastic surgery.Methods Compared with 150 cases of Han youth in the same school,the somatological survey was carried out in 150 female Uighur college students with the morphological characteristics of the eyes and good facial harmony.SPSS 17.0 was used for statistical analysis of the measured data in groups divided according to different race.Results 59.3% (89/150) of the Uighur young women had prominent brow ridges tall nose and superior orbit cave,18.7% (28/150) of them were similar to the Han type of eye,and 22.0% (33/150) in between.The rate of epicanthus in Uighur women was 28.0% (42/150),which was significantly lower than the Han nationality women 62.7% (94/150).Double eyelid incidence was 96.7% (145/150),which was significantly higher than that of Chinese Han women 67.3% (101/150).There was a no statistically significant difference between them in palpebral fissure length inner canthic diameter and outer canthic diameter (P>0.05),but a statistically significant difference was found in the height of palpebral fissure,the width of double eyelid and the distance between the eyebrow eyelid (P<0.05).Conclusions The Uighur women's eye morphology has dual characteristics of Caucasoid and Mongoloid.The data have great significance and value in guiding the eye's cosmetic plastic surgery.
7.Purification of Spirulina sp.
Xu-Hua GAN ; Xin-Yun TANG ; Guang-Jin LIU ; Cheng-Ying SHI ; Ben-Fan WANG ;
Microbiology 1992;0(02):-
Growth patterns of trichome and contaminative bacteria in Spirulina sp. liquid culture were observed, and it was found that the number of neutral and alkalophilic bacteria was always 105~106 times of that of Spirulina sp. trichome. It would be very difficult to get real pure Spirulina sp. strain by classical methods of dilution plate, capillary and single trichome selecting methods. A great deal of contaminative bacteria was washed out by two pretreatment processes. Low speed centrifugation was designed to wash the strains which usually deposit at bottom, and filtration method was designed to treat the strains usually floating at surface. Sandwich plate and dilution plate were designed for the purification of the mobile strains and non-mobile strains, respectively. A lot of strains were purified by the above processes and pure single trichome formed pure colonies on plates.
8.Expression and diagnostic value of 14-3-3 protein in brains of patients with Creutzfeldt-Jakob disease
Shi-He LIN ; Jie-Xu ZHAO ; Xue-Fan YU ; Jun-Ge ZHANG ; Yun-Tian YANG ;
Chinese Journal of Neurology 2000;0(05):-
Objectives To investigate the expression and diagnostic value of 14-3-3 protein in brains of patients with sporadic Creutzfeldt-Jakob disease(sCJD).Methods 14-3-3 protein was immunohistochemically analyzed in tissue from the frontal lobe of 5 patients with sCJD and 4 non-CJD eases Using 14-3-3 ?and ?antibodies with reference to the results of KB,GFAP and PrP detection.Results The expressions of 14-3-3 protein in five brains of sCJD were more obviously,mostly in gray matters and astrocytes in three cases.The concentration was related to PrP deposition type,but not related to prion protein genotype.Except few expression of 14-3-3 protein in neurous of two cases of acute contusion,there were no expression in the other two cases in control group.Conclusions The expression of 14-3-3 protein in brain is useful to pathological diagnosis of CJD.
9.Therapeutic response of radiosynovectomy with ~(32)P colloid in haemophilic synovitis of adolescents
lei, JIANG ; pei-yong, LI ; ping, HAO ; yi-fan, ZHANG ; xu-feng, JIANG ; su-yun, CHEN
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(11):-
Objective To evaluate the efficacy of radiosynovectomy with 32P colloid in haemophilic synovitis of adolescents. MethodsRadiosynovectomy with 32P colloid was primary performed on 26 male haemophilic patients(26 joints),whose average age was 16 years(11 to 21 years).The average dose of 32P colloid was 2.1 mCi(1.0 to 3.0 mCi). Results After 6-month interval,haemarthrosis was reduced by no less than 30% in 23 patients,with a total efficacy of 88.5%.The mean frequency of haemarthrosis was reduced from 1.9 per month of presynovectomy to 0.3 per month of postsynovectomy(P
10.Clinical study on the elderly patients with idiopathic/immune thrombocytopenic purpura
Yun FAN ; Naibai CHANG ; Baoli XING ; Lei PEI ; Yuanming LI ; Xichun GU ; Xiaodong XU
Chinese Journal of Geriatrics 2008;27(4):276-278
Objective To explore the clinical characteristics,therapy reactions and prognosis of the elderly patients with idiopathic thrombocytopenic purpura(ITP). Methods A total of 43elderly ITP patients(age≥60 years old)including 16 men and 27 women were reviewed and further followed up for 1 month to 15 years. Results Until June 2007,35 elderly ITP patients survived,platelet counts were sustained(30-50)×109/L in 7 cases,but no significant bleeding was found.Thirty-six patients had adrenocorticosteroid therapy first, 25 patients were sensitive to adrenocorticosteroid therapy,4 patients underwent splenectomy,and 3 patients achieved a normal platelet count. Immunosuppressive agents(vinscristine,cyclophosphamide, azathioprine and Cyclosporin A)treatments were held in 5 6 case-times,Cyclosporin A and azathioprine were more effective than vinscristine and cyclophosphamide.The refractory rate was 13.9%.One patient progressed to monoclonal gammopathy of unknown significance and 1 to lymphoma.Eight patients died.1 patient died of brain bleeding after trauma,3 patients died of malignant neoplasm,4 patients died of heart failure induced by infection. Conclusions The clinical features of elderly ITP patients are atypical.the mortal bleeding in them was rare,treatment strategy should be individualized tO each elderly patient.