1.Main points in building large-scale medical equipment room
Chinese Medical Equipment Journal 1989;0(04):-
This paper discusses the main points in building the large-scale medical equipment room from such aspects as the planning,designing and construction.It provides solutions to the problems which may occur in the building,and offers some suggestions.
2.Difference of colon cancer and rectal cancer-from the view of an oncological physician.
Chinese Journal of Oncology 2010;32(5):321-323
Antineoplastic Combined Chemotherapy Protocols
;
therapeutic use
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Chemotherapy, Adjuvant
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Chromosomal Instability
;
Colonic Neoplasms
;
drug therapy
;
genetics
;
pathology
;
Deoxycytidine
;
analogs & derivatives
;
therapeutic use
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Fluorouracil
;
administration & dosage
;
analogs & derivatives
;
therapeutic use
;
Humans
;
Leucovorin
;
administration & dosage
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Microsatellite Instability
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Neoadjuvant Therapy
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Neoplasm Staging
;
Organoplatinum Compounds
;
administration & dosage
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Prognosis
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Rectal Neoplasms
;
drug therapy
;
genetics
;
pathology
;
Risk Factors
5.More attention should be paid to the understanding of gastroenteropancreatic neuroendocrine tumors.
Chinese Journal of Oncology 2012;34(2):158-160
Antibodies, Monoclonal, Humanized
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therapeutic use
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Antineoplastic Agents
;
therapeutic use
;
Antineoplastic Combined Chemotherapy Protocols
;
therapeutic use
;
Bevacizumab
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Gastrointestinal Neoplasms
;
classification
;
epidemiology
;
therapy
;
Humans
;
Indoles
;
therapeutic use
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Neuroendocrine Tumors
;
classification
;
epidemiology
;
therapy
;
Octreotide
;
therapeutic use
;
Pancreatic Neoplasms
;
classification
;
epidemiology
;
therapy
;
Peptides, Cyclic
;
therapeutic use
;
Pyrroles
;
therapeutic use
;
Sirolimus
;
analogs & derivatives
;
therapeutic use
;
Somatostatin
;
analogs & derivatives
;
therapeutic use
6.Toward more understanding of esophagogastric cancer.
Chinese Journal of Oncology 2011;33(11):801-803
Antibodies, Monoclonal, Humanized
;
therapeutic use
;
Antineoplastic Agents
;
therapeutic use
;
Chemoradiotherapy
;
Chemotherapy, Adjuvant
;
Esophageal Neoplasms
;
classification
;
pathology
;
surgery
;
therapy
;
Esophagogastric Junction
;
Humans
;
Stomach Neoplasms
;
classification
;
pathology
;
surgery
;
therapy
;
Trastuzumab
7.Effects of antisense oligonucleotide of connective tissue growth factor on apoptosis of hypertrophic scar fibroblasts and the related mechanism
Academic Journal of Second Military Medical University 2000;0(08):-
Objective:To explore the effects of antisense oligonucleotide(ASODN)of connective tissue growth factor (CTGF)on the apoptosis of human hypertrophic scar fibroblasts(HSF)and the related mechanisms.Methods:The hypertrophic scar fibroblasts were cultured in vitro and were divided into the following 3 groups:CTGF-ASODN-treated group, liposome control group and blank control group.The distribution of CTGF-ASODN in HSF of different phases was observed under fluorescent microscope in 3 groups.Flow cytometer was employed to detect the apoptotic rate of HSF and the expression of Fas.The expression of CTGF,Fas and bcl-2 mRNA in HSF was assessed by RT-PCR.Results:24 h after transfection,large quantity of yellow-green fluorescence was seen in the HSF cytoplasm of CTGF-ASDON group in a scattered or doted manner, but not found in that of the other 2 groups.The apoptosis rate of HSF in CTGF-ASDON group was significantly higher than those in the other 2 groups(P
8.Relationship between coronary slow flow and vascular inflammatory factors
Chinese Journal of cardiovascular Rehabilitation Medicine 2014;23(5):494-497
Objective:To explore the relationship between coronary slow flow (CSF) and vascular inflammatory fac-tors .Methods :A total of 229 inpatients with normal coronary angiography (CAG) results were selected as research object .According to CAG TIMI flow and corrected TIMI frame count ,patients were divided into CSF group (n=102 ,no obvious lesion in epicardial coronary artery but coronary flow was slow ) and normal coronary group (n=127 ,completely normal epicardial coronary artery and blood flow ) .General clinical data were collected ,vascular inflammatory factors were measured and their relationship with CSF was analyzed .Results:Compared with normal coronary group ,there were significant rise in levels of high sensitive C reactive protein [ (1.41+0.72 ) mg/L vs . (2.82+0.58) mg/L] ,interleukin 1 [ (0.18 ± 0.05)μg/L vs .(0.26 ± 0.06)μg/L] and interleukin 6 [ (0.363 ± 0.016) ng/L vs .(0.465 ± 0.015) ng/L] in CSF group , P<0.05 all .Logistic regression analysis indicated that vas-cular inflammatory factors were risk factor for CSF occurrence (OR= 1.008 , P= 0.015 ) .Conclusion:Coronary flow velocity is closely related to vascular inflammatory factors .
9."Exploration of the Professional Spirit Cultivation with ""Double Teacher"" Method for Medical Students Based on Preeminent Doctors Education and Training Plan"
Chinese Medical Ethics 2016;29(5):759-762
Medical students′ professional spirit cultivation is an important content as well as a basic require-ment of the Preeminent Doctor Education and Training Plan. Currently, there are several problems in medical tal-ents′professional spirit cultivation, such as the unstandardized curriculum, the lack of subjective experience, and the ignorance of the unity of education stages, student differences and coherence. This study intends to explore thedouble teacher method, in which both clinical teaching doctors and medical ethics teachers engage in the medi-cal students′professional spirit cultivation. Its purpose is to build a bridge between medical ethics education in uni-versities and the clinical practice, and further to integrate them through doctors′ and teachers′ joint participation, which will significantly enhance medical students′practice ability of medical moral.
10.Inhibition of p38 MAPK kinase enhances diallyl disulfide-induced apoptosis in human CNE2 cells
Chinese Pharmacological Bulletin 1986;0(04):-
AIM To investigate the effects of p38 MAPK signaling on diallyl disulfide ( DADS ) induced apoptosis in CNE2 cells. METHODS Morphological changes and quantification of apoptotic cells were determined under fluorescence microscope after a 24 h treatment of CNE2 by DADS. Cell viability was determined with MTT method. Apoptosis detection was taken to the cells on flowcytometry. The expression of phospho p38 MAPK was measured by Western blotting. RESULTS After treatment with DADS at 50~150 ?mol?L -1 for 24 h,DADS elicited typical apoptotic morphologic changes (chromatic condensation, nucleus fragmentation). The amount of apoptosis cells increased in a concentration dependent manner but cell cycle arrest did not at 50~150 ?mol?L -1 ,incubation of CNE2 with DADS for 24 h also induced phospho p38 MAPK expression in a concentration dependent manner. Interestingly, DADS induced apoptosis was markedly increased by preincubation with SB203580, a specific p38 MAPK inhibitor,and increased the expression of phospho p42/ p44 CCDPK in a concentration dependent manner. CONCLUSION DADS activates p38 MAPK,and phospho p38 MAPK signaling appears to play protective roles in DADS induced apoptosis in CNE2.