Photography of slit-lamp biomicroscopy combined with retro-illumination photography is the gold standard in cataract evaluation. However the application is limited due to its complexity and low efficiency. We introduce digital non-mydriatic fundus photography as a new method for cataract screening in patients with visual impairment,which might play an important role in screening low vision and blindness caused by cataract. Two distinguished benefits are found in this method including compatibility for tele-diagnosis,and integration with screening of glaucoma and diabetic retinopathy. Cautions should be made on the photographs in which media opacity derived from other than cataract or low quality photos due to small pupils.

Age-related macular degeneration ( AMD ) is the main cause of blindness in the people older than 50 years old. In recent years, following the improvement of imaging techniques in ophthalmology, the pathogenesis of the disease, the level of diagnosis and efficacy evaluation ability greatly improved. In this paper, we reviewed and discussed the recent advancement on imaging research of age-relate d macular degeneration.

Private cloud is an internal cloud featuring multi-tenant,dynamic configuration and optimization infrastructure,which enables developers to achieve service self-deployment and self-hosting within security coverage of the enterprise data center.This paper introduced the concept of cloud computing.Then it went on to present the private cloud architecture of the hospital by analysis of problems in the hospital including information construction costs,management and maintenance,and information expansion.In the end,the authors analyzed the cloud computing service model,hospital private cloud architecture,along with outcome analysis for hospital private cloud implementations.

Objective To compare the influence of different end-tidal concentrations of sevoflurane on transcranial electrical four-limb muscle motor evoked potential (MEP) monitoring. Methods Twenty ASA Ⅰ-Ⅱpatients aged 23-62 years undergoing craniotomy were enrolled. Triangular muscle, biceps brachii muscle, triceps brachii muscle, brachioradialis muscle, extensor digitorum communis muscle, abductor pollicis brevis abductor digiti minimi muscle, rectus femoris muscle, tibialis anterior muscle, gastrocnemius muscle and abductor hallucis were selected for MEPs recording. Sevoflurane was introduced at 0.5, 0.75, 1.0 and then 1.3 MAC (15 min each), and the effects on MEPs were studied. Results ①Maximum MEP amplitude was observed at abductor pollicis brevis muscle in upper limb and abductor hallucis muscle in lower limb at baseline and 0.5 MAC. Up to 1.0 MAC, there was no significant difference in MEP amplitude among extensor digitorum communis muscle, abductor pollicis brevis and abductor digiti minimi muscle. ②The success rate of MEP recording from abductor pollicis brevis muscle and abductor hallucis muscle was 100% during the administration of 0.5-1.0 MAC sevoflurane. ③The MEP amplitude was decreased and the latency was increased in a sevoflurane dose-dependent manner. Conclusions Abductor pollicis brevis muscle and abductor hallucis muscle were suitable for MEP monitoring during the administration of 0.5-1.0 MAC sevoflurane.

Objective To investigate whether the extact of ginko biloba (EGb761) can protect the retinal ganglion cells (RGC) after acute high intraocular pressure induced retinal ischemia-reperfusion injury. Methods Thirty Sprague-Dawley rats were randomly divided into three groups. The negative control group, positive control group, treatment group were given normal saline 5 mL/kg, 1% erigeron breviscapus (vant) hand-mazz (EBHM) 5 mL/kg, 1% EGb761 5 mL/kg, respectively 2 hour after injury and every day after operation. Retinal ganglion cells were retrograde labeled by injection of 3% fluorogold (FG) into both side of superior colliculus 5 days before the death of the rats. Results The average survival rate of retinal ganglion cells were 61.46%, 72.73% and 76.20% in negative control group, positive control group and treatment group respectively. Conclusion EGb761 has neuroprotective effect on retinal ganglion cells in acute high intraocular pressure induced retinal ischemia-reperfusion injury.

Objective To investigate Hysterothylacium aduncum (Anisakidae) infection in marine fishes from Bohai Sea and Yellow Sea. Methods Nematodes were collected from the digestive tract of fishes, fixed with hot 4% formalin and preserved in 70% ethanol for study. The specimens were cleared in lactophenol for light microscopical examination, and properly treated for scanning electron microscopy (SEM). Results Among the fishes examined, 14 out of 93 species (15.1%) were found infected by H.aduncum, with a higher prevalence in the fish of Lophius litulon(66.7%), Scomber-omorus niphonius(47.5%), and Gadus macrocephalus(33.3%). H.aduncum infection was first recorded in elasmobranch-Raja smirnovi. Morphological differences of H.aduncum were observed, including the width of lateral alae and the length of intestinal caecum. Conclusion H.aduncum in fishes of Bohai Sea and Yellow Sea in China may be a complex species, and its high prevalence in some fishes reminds the risk of anisakiasis by eating raw fishes.

Objective To observe the effect of Yinhuang freeze-dried powder injection on nervous system of rats and mice,and to probe its safety.Methods After injected Yinghuang freeze-dried powder injection nerve system and general behavior of rat or mouse were observed.Results Yinghuang freeze-dried powder didn’t affect rat’s or mouse’s general behavior,but had certain central nevous system suppression function in rats and mice.Conclusion Yinghuang freeze-dried powder have certain central nevous system suppression function in rats and mice.

Objective To observe the rat chronic toxicity induced by Yinghuang freeze-dried powder injection. Methods The rats were given Yinghuang freeze-dried powder injection for 35 days with the doses of 166.5, 82.25, 41.12 mg/kg and for 15 days of stopping administration. The index sign of hematology and biochemistry were determined, and the pathological examination were carried out. Results The rat were given Yinghuang freeze-dried powder injection for 35 days and for 15 days of stopping administration. Mostly index sign of hematology and biochemistry had no significant difference by comparing with the control. There exceptional index sign of exceptional dosage group have significant difference by comparing with the control. But these exceptional index sign fluctuated in normal range in the laboratory. The pathological examination did not discover significant pathological changes related to drug toxicity. Conclusion Yinghuang freeze-dried powder injection has no significant toxicity for long-term administration on rats. It infers that the drawing up doses in clinic will be safe.

Objective To investigate the effectiveness of interventional therapy for the atherosclerotic renal artery occlusion (ARAO). Methods During the period of June 2001-Dec. 2007, 16 patients with ARAO (total of 16 occluded arteries) underwent interventional managements, including percutaneous endovascular renal artery revascularization, balloon dilatation angioplasty and stent placement. Follow-up survey was made at regular intervals. The patent condition of the renal artery was evaluated with ultrasonography and digital subtraction angiography. The blood pressure and the renal function were determined and the data were statistically analyzed in order to assess the intermediate and long-term effect of the interventional therapy. Results Of 16 patients, technical success was achieved in 15 (93.8%) and failure occurred in one. During a follow-up period of 9 - 24 months, 3 patients died. According to the data obtained at each patient’s last follow-up survey, the hypertension fell to normal in 3 (25.0%), was improved in 7 (58.3%) and showed no marked change in 2 patients (16.7%), with a clinical efficacy of 83.3% (10 / 12). The renal function was improved in 2 (16.7%), stabilized in 6 (50%) and deteriorated in 4 patients (33.3%), with an effective rate of 66.7% (8 / 12). Conclusion For the treatment of atherosclerotic renal artery occlusion, the interventional therapy carries high successful rate and can effectively lower the blood pressure level, in addition, it can also protect the renal function in a certain degree.

ObjectiveTo study the characteristics of wedge factor of enhanced dynamic wedge (EDW) on Varian 600C linear accelerator . MethodsEnhanced dynamic wedge factors (EDWFs) of different jaw settings were measured on a Varian 600C linear accelerator with FARMER 2570 dosimeter and 2571 0.6 ml Thimble ion chamber. At the same time,equations were used to compute EDWFs of symmetric and asymmetric fields and off axis points. The same measurements were carried out on 30 degree physical wedge in contrast to EDW. The accelerator's jaw position was described according to IEC radiotherapy equipment coordinate standard. Results The EDWFs of symmetric field decreased smoothly while the field size increased. Under the same field,EDWFs decreased as the wedge angle increased and the increasing extent became apparent when the field became larger. In off axis fields formed by the upper independent jaws,only the EDWFs of 60 degree had the tendency to increase when the field center moved toward the toe of the wedge,the rest gave the opposite results. The EDWFs of fixed points varied only by 0.5 percent when the fixed jaw remained at the same place and the moving jaw and lower jaws stayed at different positions. But the WF of 30 degree physical wedge increased by 2.9 percent when the lower jaw settings increased from 4 cm to 40 cm. The EDWFs derived from analytic equations for symmetric and asymmetric fields coincided well with measured results. But at off-axis points,the differences between calculated values and measured data were apparent. ConclusionsThe curve of EDWF versus field size is very smooth. The EDWF of fixed point only depends on the position of the stationary upper jaw,and is affected little by the moving upper jaw and lower jaws. The EDWFs of off axis fields are much more complex than those of physical wedge; it shouldn't be confused in clinical application. The conversion method of rectangular field to square field is of no use when EDW field is confronted. Analytic methods are highly conformal with the calculation of EDWFs of symmetric and asymmetric fields.