1.A retrospective study on syphilis infection and its epidemiological characteristics
International Journal of Laboratory Medicine 2014;(10):1295-1296
Objective To analyze the results of syphilis test and to understand the syphilis infection and its epidemiological characteristics .Methods 728 untreated patients with definite diagnosis of syphilis were enrolled and classified according to their age ,gender and syphilis types ,and retrospectively analysis was conducted .Results Among 728 syphilis patients ,446(61 .26% ) were diagnosed with latent syphilis ,211 (28 .98% ) with dominant syphilis ,32(4 .40% ) with neurosyphilis and 39(5 .36% ) with congenital syphilis .The average detection rate of syphilis was 1 .49% .332(45 .60% ) cases were found in female patients while 396 (54 .40% ) in male .Male syphilis patients were mainly in the 20 to 60 age group ,and female in the 20 to 50 age group .Dominant syphilis occurred mainly in the 20 to 40 age group and latent syphilis in the 20 to 60 age group .Conclusion The detection rate of syphilis increases year by year ,with the highest growing rate in latent syphilis and young adults as major incidence groups .
2.Influence of structural psychological intervention on negative emotion of hemodialysis patients during the induction period
Chinese Journal of Primary Medicine and Pharmacy 2017;24(5):732-735
Objective To investigate the influence of structural psychological intervention on negative emotion of hemodialysis patients during the induction period.Methods 90 hemodialysis patients in induction period were divided into intervention group(structural psychological intervention group,45 cases)and control group(conven-tional nursing group,45 cases)by the method of random number table.The satisfaction degree of nursing after two weeks nursing and negative emotional state before and after intervention were compared between the two groups. Results The satisfaction degree of the intervention group after nursing was 95.5%,which was higher than 84.5% of the control group(χ2 =6.362,P <0.05).The SAS score and SDS score of the two groups before nursing had no significant differences(t =2.41,1.78,all P >0.05).While the SAS score and SDS score of the intervention group after nursing were significantly better than before intervention(t =4.87,6.62,all P <0.05).And the SAS score and SDS score of the intervention group after nursing were significantly better than those of the control group(t =5.76, 8.43,all P <0.05).Conclusion Structural psychological intervention on hemodialysis patients with uremia during the induction period can increase the nursing satisfaction of patients,relieve the anxiety and depression of hemodialysis patients during the induction period.
3.Drug Utilization in 690 Nationwide Sample Hospitals During 2005~2006
China Pharmacy 2005;0(17):-
OBJECTIVE:To evaluate the drug utilization in nationwide sample hospitals so as to provide information for the production, management and utilization of drugs. METHODS: The drug utilization data in nationwide 690 hospitals during the period 2005 ~2006 were analyzed statistically. RESULTS & CONCLUSION: Anti-infective drugs, cardiovascular drugs, biological products and biochemical drugs have been ranking among the first 3 places in consumption, but their consumption sum showed a downward trend. The consumption sum of anti-tumor drugs, Chinese formulated products, digestive system drugs, and respiratory system drugs showed an upward trend. The top 20 drugs on the list of consumption sum were mainly antibiotics. The consumption quantity and consumption sum of anti-tumor drugs showed an upward trend. Of the top 10 manufacturers in terms of consumption sum, the imported manufacturers took a small proportion while the joint venture took a higher proportion.
4.Comparision of Relief Fund System for Adverse Drug Reactions in Japan and Taiwan Area and the En-lightenment to China
China Pharmacy 2017;28(22):3036-3039
OBJECTIVE:To provide reference for constructing relief fund system for adverse drug reactions(ADR)in China. METHODS:Referring to the ADR damage relief system in Japan and Taiwan area of China,comparative study was conducted from aspects of the legal basis of the fund establishment,the nature of the authority,financing sources and ratio,relief efforts,etc. And rationalization suggestions were put forward for constructing the relief fund system for ADR in China. RESULTS & CONCLU-SIONS:The ADR damage relief fund system of Japan and Taiwan area of China was established by the law. However,due to dif-ferent administrative system,financing sources and ratio,and relief efforts,there were some similarities (setting related laws, showing similarities in the partnerships between authorities and its health departments)and differences(the nature of fund authori-ties were independent administrative body in Japan,independent corporation in Taiwan area of China and so on)in the elements of the financing model. When constructing the ADR relief fund system,China should accelerate the relevant legislation;the govern-ment should reasonably arrange fund management agency,gradually establish ADR damage relief fund step by step,enhance the public awareness of ADR damage relief fund and establish diversified financing modes with enterprise-based payment.
5.Discussion in bilingual teaching of vocational medical education
Huili ZHANG ; Yilan ZHANG ; Feng XU
Chinese Journal of Medical Education Research 2011;10(12):1434-1436
It is necessary to carry out bilingual teaching in medical vocational education.However,there are many difficulties of bilingual education,such as paying insufficient attention to bilingual education in the schools,the lack of bilingual education teachers and unevenness of students in English.In order to solve the problems the medical vocation schools should develop policies and methods of bilingual education and enhance bilingual teacher training and increase the investment of both hardware and software for bilingual teaching.
6.Effect of addition of various doses of fentanyl intrathecally on perioperative analgesia and subarachnoid block characteristics in inguinal hernia repair surgery
Feng XU ; Fayin LI ; Jun ZHANG
Chinese Journal of Postgraduates of Medicine 2011;34(27):16-19
ObjectiveTo study the effect of adding various doses fentanyl to 0.75% bupivacaine for spinal anesthetic in the population undergoing inguinal hernia repair surgery. MethodsThe population of 100 patients belonging to ASA class Ⅰ and Ⅱ ,scheduled for elective inguinal hernia repair, were randomized to receive a spinal anesthetic with 2 ml 0.75% bupivacaine and 1.0 ml saline (group B),or 50 μg/ml fentanyl 0.1,0.2,0.4,0.6 ml(group BF5, group BF10, group BF20,group BF30),each group with 20 cases.Subarachnoid block was established in the left lateral position in L2-3 space by use of a midline approach. The volume of injected drug was kept constant at 3 ml. The time to the highest level of sensory block, the time for regression until T12 level, the time for complete motor recovery, the maintenance duration of the analgesia,the anesthesia effect of the groups, duration of surgery, drug-related side effects were assessed and recorded.ResultsThe time of the highest level of sensory block in group BF30 was shorter than that in group B,group BF5, group BF 1 0, group BF20 (P < 0.05 ), but group B and group BF5 was longer than group BF10,group BF20, group BF30(P < 0.05 ). The time of regression to T12 level in group BF20 was longer than that in group B, group BF5, group BF10, group BF30 (P<0.05),but group B and group BF5 was shorter than group BF10, group BF20, group BF30(P< 0.05 ). The time for complete motor recovery and the maintenance duration of the analgesia in group B and group BF5 was shorter than that in group BFI0,group BF20, group BF30 (P < 0.05 ). The occurrence of pruritus in group B (0) was lower than that in group B F5 (8 cases),group BF10 (3 cases), group BF20 (6 cases), group BF30 (6 cases)(P<0.05). There were no cases of respiratory depression in five groups. ConclusionsIt suggests that in the population receiving spinal anesthetic for hernia repair surgery, addition of 10 μ g fentanyl to 0.75% bupivacaine significantly improves the quality and duration of analgesia. No further advantage occurs if the dose of fentanyl is increased among 30 μg.
7.Biological therapy of ovarian cancer
Huiru XU ; Huijing FENG ; Junping ZHANG
Journal of International Oncology 2013;40(11):861-864
In recent years,the biological therapy of ovarian cancer has made great progress.Immunotherapy including tumor vaccine and adoptive immunity cell therapy can improve immune recognition capability,while the applications of molecular targeted drugs such as monoclonal antibodies and tyrosine kinase inhibitors for different target spots during the tumor cells growth progresses achieve significant clinical benefit,as well as hormone replacement therapy and Chinese medicine treatment improve the life quality of patients with ovarian cancer to a certain degree.
8.Detection of mutations of the dystrophin gene in Duchenne muscular dystrophy boys.
Rong HUANG ; Jin-feng ZHANG ; Jun XU
Chinese Journal of Pediatrics 2009;47(1):68-69
Child
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DNA Mutational Analysis
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Dystrophin
;
genetics
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Exons
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Humans
;
Male
;
Muscular Dystrophy, Duchenne
;
genetics
;
Mutation
10.Extranodal follicular dendritic cell sarcoma of neck region: report of a case.
Chinese Journal of Pathology 2012;41(6):410-411
Antineoplastic Combined Chemotherapy Protocols
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therapeutic use
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Carcinoma
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metabolism
;
pathology
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Cyclophosphamide
;
therapeutic use
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Dendritic Cell Sarcoma, Follicular
;
drug therapy
;
metabolism
;
pathology
;
surgery
;
Diagnosis, Differential
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Doxorubicin
;
therapeutic use
;
Head and Neck Neoplasms
;
drug therapy
;
metabolism
;
pathology
;
surgery
;
Humans
;
Lung Neoplasms
;
drug therapy
;
secondary
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Male
;
Melanoma
;
metabolism
;
pathology
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Middle Aged
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Neoplasm Recurrence, Local
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Prednisone
;
therapeutic use
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Receptors, Complement 3b
;
metabolism
;
Receptors, Complement 3d
;
metabolism
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Vincristine
;
therapeutic use