2.Mechanism Study on Intestinal Microecology of Children Recurrent Respiratory Tract Infection Prevented and Treated with Method of Activating Spleen to Solidify Superficial
Shuanghong XU ; Xiaogang CHEN ; Xiaoying HU
Journal of Zhejiang Chinese Medical University 2006;0(02):-
[Objective] To explore the effect of the method of activating spleen to solidify superficial on intestinal microecology of children recurrent respiratory tract infection.[Method] Select 60 cases aged 1~12 of Qi deficiency type of lung and spleen in recurrent respiratory tract infection,randomly divide them into treatment group 30 cases and control 30;the treatment one takes TCM Fugangning formula orally for activating spleen to solidify superficial;the other takes orally BIFICO,for 12 w;compare their Bifidobacteria(B) and Escherichia coli(E) changes and B/E value after treatment,compare it to the control one's.[Result] After treatment,in the dejecta samples,the B content was higher than that in control one(P0.05);the B and E content and B/E were lower than normal group(P0.05),while control group was more than the normal group(P
3.Midterm follow-up of surgical treatment for ischemic mitral regurgitation
Lei CHEN ; Shengshou HU ; Jianping XU
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(03):-
Objective To report the surgical technique and clinical results for surgical treatment of ischemic mitral regurgitation, and midterm follow-up results. Methods From December 1996 to April 2002, 55 patients underwent surgical treatment of ischemic mitral regurgitation. There were 45 males, 10 females with a mean age of (56.63?9.31) years . The cardiac function were NYHA class I~II 7 cases and class III~IV 48 cases. There were 9 mild MR, 28 moderate MR and 18 severe MR. Forty-six patients treated with CABG and concomitant mitral valve correction. Results No operative and postoperative death, No postoperative severe complications. Fifty-three patients were followed up for a mean duration of (45.3?18.7) months, At 5 years and 10 years, survival and event-free survival rates were 85.2% and 72.4%,freedom from reoperation were 82.7% and 70.6%. Conclusion Mitral valve surgery is indicated in patients undergoing coronary artery bypass graft surgery who have moderate or severe ischemic mitral regurgitation,the mitral valvuloplasty was the first select, and the midterm follow-up outcome are satisfactory.
4.Experimental study on the cardiomyocyte apoptosis in the early myocardial ischemia
Bingjie HU ; Jianguo CHEN ; Xiaohu XU
Chinese Journal of Forensic Medicine 1986;0(02):-
In order to explore the significance of cardiomyocyte apoptosis in the early myocardial ischemia,the rat model of acute myocardial ischemia was established,and the apoptotic cells were detected in the early phase of ischemia(within 6h)with TUNEL method.The results showed that scanty apoptotic cells could be observed in the ischemic region 1h after ischemia,and reached the peak 3h after ischemia,then decreased.No apoptotic cells were found in the normal region.In the peri ischemic region,apoptotic cells could also be observed 1h after ischemia,and reached the peak 5h after ischemia.It is indicated that apoptosis is the major form of early ischemic myocardial damage,and the detection of apoptotic cardiomyocyte may provide a new sensitive and objective method for the postmortem diagnosis of early myocardial infarction.
5.Hospital forum-based health information service for patients
Xu CHEN ; Shengchao HOU ; Hong HU
Chinese Journal of Medical Library and Information Science 2017;26(5):64-67
After the health information service for patients in hospitals was described,its characteristics,service process and management model were elaborated,which showed that the clear and reliable sources of hospital forum-provided medical and health information could serve the patients more effectively.
6.Application of acceptance and commitment therapy in borderline personality disorder
Zhizhong HU ; Maorong HU ; Jinyuan CHEN ; Jing XU ; Jiyao PANG
Chinese Journal of Behavioral Medicine and Brain Science 2021;30(1):84-89
Borderline personality disorder (BPD) is characterized by emotional regulation, interpersonal relationship, self-image and impulse control instability. It is a mental disorder with high morbidity, high mortality and difficult treatment. Psychotherapy is the main treatment for this disease. However, current mainstream psychotherapy, such as dialectical behavior therapy (DBT), has certain limitations, so it is necessary to find a more convenient and effective treatment method. Acceptance and commitment therapy (ACT), as the representative therapy of the third generation of cognitive therapy, aims to make individuals accept inevitable pain, find their own value and commit to action, and finally improve their psychological flexibility to live a meaningful life. ACT has been used in the treatment of a variety of mental disorders, and the effect is significant. By expounding the pathogenesis of BPD and the theoretical model of ACT, this paper analyzed the rationality and feasibility of ACT intervention in BPD from the pathological model and treatment model of ACT. Finally, the research results of ACT treating BPD in recent years were summarized. The results show that ACT provides a promising method for the treatment of BPD patients, however, more studies are needed to prove its use in this group and its specific mechanism.
8.Voriconazole Therapy of Fungal Infections in Patients with Hematologicy Malignancies
Zhiyong YU ; Xiaoying ZHANG ; Botao LI ; Chen XU ; Hu CHEN
Chinese Journal of Nosocomiology 2004;0(10):-
OBJECTIVE To report malignant hematologic patients suffered in fungal infections treated with voriconazole(VOR),compare them with other similar patients treated with aluphotericin B liposome(L-AMB) as control,and then review the references.METHODS Fifty patients were treated with VOR and 57 patients were treated with L-AMB.According to the clinical performance and the changes in the CT,we could find the difference of between them.RESULTS Forty cases were effective in VOR group and most of them were in good tolerance.In the control group,37 cases were effective,most of them were in poor tolerance,and some of them stopped the treatment.CONCLUSIONS Instead of L-AMB,VOR can be a useful drug in the treatment of hematologic malignancies patients suffered in fungal infections.
9.Clinical Study of Combined Acupuncture and Tuina in Treating Enuresis Following Occult Cleft Spine
Zhenxia HU ; Qing JI ; Qiang CHEN ; Hong XU ; Zuolin CHEN
Journal of Acupuncture and Tuina Science 2004;2(5):11-13
To observe the clinical efficacy of combined acupuncture and Tuina in the treatment of enuresis following occult cleft spine and seek quantified indexes for result assessment, 40 subjects were treated by above methods and B-ultrasonically examined before and after treatment to determine the capacity of bladder and the residual urine inside it. The total effective rate was 90%; there was a difference of the capacity of bladder between before and after treatment (P<0.05); 11 cases suffered from residual urine, and there was also significant difference of residual urine between before and after treatment (P<0.01). It is revealed that this method can increase the capacity of bladder and diminish residual urine.
10.Late identification and its influencing factors of newly reported HIV/AIDS cases in Shangcheng District from 2013 to 2022
XU Yimei ; CHEN Yani ; HU Jinfeng ; CHEN Wanjun
Journal of Preventive Medicine 2024;36(3):243-246
Objective:
To investigate the late identification and its influencing factors of newly reported HIV/AIDS cases in Shangcheng District, Hangzhou City, so as to provide insights into the development of strategies for early detection and identification of HIV/AIDS cases.
Methods:
Basic information, identification routes and CD4+T lymphocyte counts among newly reported HIV/AIDS cases in Shangcheng District from 2013 to 2022 were collected through the Chinese Disease Prevention and Control Information System. The proportion of late identification of newly reported HIV/AIDS cases was analyzed, and factors affecting late identification was analyzed by a multivariable logistic regression model.
Results:
Totally 1 052 HIV/AIDS cases were newly reported in Shangcheng District from 2013 to 2022, including 1 011 males (96.10%), and had a mean age of (32.90±12.39) years. There were 333 cases with late identification, accounting for 31.65%. The proportions of late identification have no significant changing trend from 2013 to 2022 (P>0.05). Multivariable logistic regression analysis showed that HIV/AIDS cases aged 25 years and older (25 to 49 years, OR=1.894, 95%CI: 1.350-2.658; 50 years and older, OR=3.010, 95%CI: 1.838-4.928) had a higher risk of late identification, while HIV/AIDS cases with college degree and above (OR=0.655, 95%CI: 0.459-0.936) and identified by voluntary counseling and testing (OR=0.542, 95%CI: 0.380-0.772) had a lower risk of late identification.
Conclusions
The proportion of late identification of newly reported HIV/AIDS cases in Shangcheng District from 2013 to 2022 was 31.65%. Age, educational level and identification route were important factors affecting late identification of HIV/AIDS cases in Shangcheng District.