1.The application of non-invasive transcutaneous monitoring of oxygen and carbon dioxide in newborns
International Journal of Pediatrics 2016;43(10):815-819
Non-invasive transcutaneous monitoring(TCM) of oxygen and carbon dioxide,with continuous,non-invasive characteristics,is in common use and significant in the neonatal intensive care unit (NICU),which can directly reflect critically ill newborns'changes of respiratory and circulatory function.This review describes how to use TCM appropriately,compares the advantages and disadvantages of TCM with other monitoring devices,introduces its application in neonatal transport and NICU.
2.Ifosfamide and other 3 drugs chemotherapy for 24 cases with recurrent intermediate—high grade non-Hodgkin's lymphoma
China Oncology 1998;0(01):-
Purpose:To study the salvage treatment of recurrent intermediate—high grade non Hodgkin lymphoma(NHL). Methods:24 cases of recurrent intermediate—high NHL were divided into two groups: 10 cases with poor prognostic factors in group one(G1), 14 cases without poor prognostic factors in group two(G2).All cases were treated with ifosfamide(IFO), mitoxantrone(Mx), pingyangmycine(PYM), prednisone(Pred) (IMPP). IFO 1.5 g/m 2 iv on days 1 to 4, and mesna iv at hours;0, 4, 8 Mx 8 mg/m 2 on day 1; PYM 5mg/m 2 im on days 8 and 15; and Pred 100mg/d po on days 1 to 5. Every 4 weeks as one cycle. Assessment was given after 2 cycles. Results:The total CR rate was 58.3%(14/24), RR 79.2%(19/24). The CR rate was 30%(3/10), RR 60%(6/10) in G1 and the CR rate was 78.5% (11/14), RR 92.8%(13/14) in G2 ,respeetively. The difference of the two groups in CR and RR was significant( P
3.Warm needling moxibustion plus PKP for vertebral compression fracture due to kidney deficiency and blood stasis: a randomized controlled trial
Journal of Acupuncture and Tuina Science 2021;19(2):133-138
Objective: To explore the efficacy and mechanism of warm needling moxibustion plus percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fracture (OVCF) due to kidney deficiency and blood stasis. Methods: A total of 70 OVCF patients were randomized into a control group and an observation group, with 35 cases in each group. The control group was given PKP treatment, and the observation group was treated with warm needling moxibustion on the basis of the treatment in the control group. The visual analog scale (VAS) and Oswestry disability index (ODI) were scored and the Cobb angle of fractured vertebrae was measured before and after treatment. The re-fracture rate of the adjacent vertebrae was recorded at 1-year follow-up. The serum levels of transforming growth factor (TGF)-β1 and omentin-1 were measured before and after treatment. Results: After treatment, the VAS and ODI scores in both groups decreased (all P<0.05), and all the scores in the observation group were lower than those in the control group (both P<0.05). After treatment, the Cobb angle of fractured vertebrae in both groups decreased (both P<0.05), and the Cobb angle in the observation group was smaller than that in the control group (P<0.05). At 1-year follow-up, the re-fracture rate of the adjacent vertebrae in the observation group was lower than that in the control group (P<0.05). After treatment, the serum levels of TGF-β1 and omentin-1 in both groups increased significantly (all P<0.05), and the serum levels of TGF-β1 and omentin-1 in the observation group were higher than those in the control group (both P<0.05). Conclusion: The treatment of warm needling moxibustion plus PKP can relieve pain, improve dysfunction, promote healing of the injured vertebrae, and reduce the re-fracture rate of the adjacent vertebrae in patients with OVCF due to kidney deficiency and blood stasis, which may be related to the increase of serum TGF-β 1 and omentin-1 levels.
5.Research on real-time monitoring indexes of medical process quality at tertiary general hospitals
Chinese Journal of Hospital Administration 2015;31(2):104-107
In the scientific,systematic,practical and feasible principles,the quality control needs and management needs of health authorities and medical institutions were analyzed.The study probed into the real-time monitoring functions of existing hospital information systems and information products of IT technology firms,and the feasibility of setting up key monitoring points during medical service processes.685 real-time monitoring indicators have been set up for real-time monitoring of medical process quality.
6.Development of new magnetic bead separation and purification instrument.
Chinese Journal of Medical Instrumentation 2014;38(3):199-201
The article describes the development of new magnetic bead separation and purification instrument. The main application of the instrument is to capture tubercle bacillus from sputum. It is a pretreatment instrument and provides a new platform to help doctors to diagnose bacillary phthisis. Not only could it be used for tubercle bacillus capturing, but also for gene, protein and cell separating and purification. Because the controller of the instrument is 16-bit single chip microcomputer, the cost could be greatly reduced and it will be widely used in China.
Cell Separation
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instrumentation
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Equipment Design
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Magnetics
7.Stroke-induced immunological alterations and relevant treatment strategies
International Journal of Cerebrovascular Diseases 2009;17(6):440-443
The changes of immune system following stroke mainly includes the local inflammatory responses of brain tissue and the systemic immunological changes, The former may exacerbate brain damage following stroke, the latter may increase the susceptibility to infection, and thus impact on brain function recovery and prognosis. Stroke interferes with the normal balance between the nervous system and the immune system, and its mechanism remains unclear. This article reviews the stroke-indnced immunological alterations and their mechanisms,as well as the corresponding treatment strategies in clinical practice.
8.Reserch development on the correlation of Bcl-2 family and tumor radiosensitivity
Journal of International Oncology 2009;36(7):504-506
Bcl-2 family plays an important role in cell apoptosis pathway. The ratio of pro-apoptosis members and anti-apoptosis members closely correlates with tumorigenesis, tumor radiosensitivity and progno-sis. Recent years ,according to the correlation of Bcl-2 family and tumor radiosensitivity, many researchers want to find new therapeutic strategies that target Bcl-2 in clinical radiotherapy.
9.Influential factors and structural equation model of creativity among medical students
Chinese Journal of Behavioral Medicine and Brain Science 2009;18(3):279-281
Objective To study current situation of creativity among medical students and its influential factors, and to explore structural equation model about influential factors of creativity. Methods The sample was randomly chosen by using cluster-based sampling method, 413 students in medical university were tested by Williams creativity scale and the influential factors of creativity questionnaire. Results Among the medical student's creativity characters, the most extrusive character was challenge(2.35±0.26), the more important were curiosity(2.29±0.28) and risk-taking(2.21±0.27), and imagination(2.04±0.33) was less important. The structural equation model of influential factors of creativity implied that mental health was the most important factor about improving medical student creativity and by changing study style could promote creativity of medical students. Conclusion By establishing structural equation model, we not only study the influential factors of creativity in realistic view, but also master important extent of each influential factors theoretically.
10.Nursing care of an elderly patient with severe pemphigus complicated with septicemia
Chinese Journal of Nursing 2009;44(12):1099-1100
This paper introduced the nursing care of an elderly patient with severe pemphigus complicated with septicemia,such as specialized skin care,treatment with hormones and antibiotics,observation of drug effects,as well as hemoculture,nutrition and psychological care.The patient cooperated well with clinical treatment and was discharged with recovery 37 days later.