Technical standards were supports that not only for any profession’s development, but also for the basic means of modern quality control.Forensic clinical medicine has developed nearly 40 years in china, there are 23 normative technical documents at present, the range of its application has been expanding with time, the caseload has been more than 1 million pieces per year all the country. Reviewing these standards, it can be seen: Technital standard of forensic clinical medicine has absorbed a large number of advanced international ideas, assimilating plenty of practice experience at the same time, standard's system has been initially formed, it has become one of the important means to guarantee the quality of medicolegal expertise. Certainly, the construction of forensic clinical standardization in China is still an arduous task, there are also many outstanding contradiction in the existing standards, our studies on international standards were not in-depth, and so on. In the future, forensic science experts still need to strengthen the companion study of technical standards and laws or regulations, intensify tracing and evaluating of international standards in order to form more adaptive and advanced technical standards.

Periodicals as Topic

Burns ; Periodicals as Topic

Objective To study the expression of inducible nitric oxide synthase (iNOS),endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) in human gastric cancer and their relationship with tumor angiogenesis and to investigate the interaction of NOS and VEGF in gastric cancer.Methods The expression and distribution of VEGF, iNOS and eNOS in 34 gastric cancer specimens were detected with immunohistochemistry. Microvessel density (MVD) was counted with FⅧRAg immune specific staining.Results The expression rates of iNOS, eNOS and VEGF in 34 gastric cancers were 73.5%, 82.4%and 91.2%respectively. The expression of VEGF had a significant positive relation with iNOS, but not with eNOS. The MVDs of VEGF or iNOS positive gastric cancers were obviously higher than those of VEGF or iNOS negative gastric cancers. There was no significant difference between the MVDs of eNOS positive gastric cancers and eNOS negative ones. Conclusion MVD increases with increase of expression of VEGF and iNOS in gastric cancer. It is indicated that VEGF and iNOS can promote gastric cancer angiogenesis. VEGF and iNOS have a significant positive correlation, which suggests that in human gastric cancer, iNOS plays an important role in the production and action of VEGF.

The theory of cancer stem cells proposed that recurrence and metastasis of liver cancer are closely related to liver cancer stem cells.The traditional surgical treatment of liver cancer simply kills those rapidly proliferating tunor cells instead of eliminating hepatic cancer stem cells which play decisive role in recurrence and metastasis.As far as people have concerned,there are many signaling pathways and regulatory factors modulating liver cancer stem cells,such as the Wnt/β-catenin pathway,TGF-β pathway,Notch pathway,Hedgehog pathway,hepatitis B virus,as well as epigenetics.Further studies on regulatory mechanisms of liver cancer stem cells are of great significance,in hope of providing new evidence for treatment and prevention of recurrence and metastasis of liver cancer.

Dendritic Cells ; pathology ; Hematologic Neoplasms ; diagnosis ; therapy ; Humans

Objective To investigate causes for Kojewnikow syndrome,by observing its clinical characteristics,electroencephalography and findings in imaging scanning. Methods Twelve patients with Kojewnikow syndrome were accessed with clinical observation, electroencephalography and imaging scanning. Results Kojewnikow syndrome is clinically charaterized by secouse twitching and simple partialis motor continua.Viral encephalitis is by far the most of common cause for Kojewnikow syndrome, followed by meningo-encephalitis,cerebral glioma,cerebral cysticercosis, cerebral infarction, diabetes, and cryptogenic epilepsyKojewnikow syndrome tends to occur in watershed area. Conclusions Kojewnikow syndrome falls into two main groups.It is important to improve the diagnosis and find the causes for Kojewnikow and to access its clinical manifestations, electroencephalography and findings in the imaging scanning.The seizures cannot be readily controlled by the anticonvulsants,so the prognosis is poor.

Objective To study the effect of individual and environmental factors of diabeties on their glycemic and lipidic metabolism. Methods While educating diabeties with diabetic informations, we inguired their individual data questionnaires. According to their diabetic periods,cultural levels,compliance to their doctors,daily work times and ocupations respectively,we grouped these patients and compared their fasting and postprandial glycemia (FBG & PBG), GHb,serum lipids and serum uric acid (BUA). Results Among 2 856 diabetic patients,the type I was about 4. 9% and the type Ⅱ about 95. 1% ; the family patients was about 9. 91% and the overweight about 44. 29K. According to patients' compliance to their doctors,blood glucose,GHb and lipids and BUA was lower in absolute compliance group than the basical group or the non compliance one (P＜0. 02),and the levels of glycemia and GHb and TG all related to their compliance (respectively r=- 0. 059, - 0. 055, - 0. 075, - 0. 063 ; and P＜0. 05, 0. 05, 0. 01, 0. 025 ). Considering the diabetes periods,the 1-5 year metabolic control of group was best (P＜0. 02) and the 5- 10 year and above 10 year metabolic control groups were better than the group within one year (P ＜0. 05). To patients' cultural levels, the metabolic control senior or higher middle school groups was better than the junior middle school or lower (P＜0. 05). Thinking their daily work time and occupation,the metabolic control of groups working more than seven hours was worst (p respectively less than 0. 05 and 0. 02). Conclusion diabetic patients' individual and environmental factors are all affecting their metabolic control,among them the complicance is most effective.

BACKGROUND: Transmitting law of laser in biological tissues is hard to calculate by mathematical analysis or clinical monitoring. Therefore, numerical simulation is commonly used for its prediction. Monte Carlo simulation is an ideal method for this study. OBJECTIVE: To establish a light dose mathematical model by Monte Carlo method, and to explore the damage of laser to liver tissues.METHODS: Light dose mathematical models of normal tissues and tumor with varied optical parameters were established by Monte Carlo method, and the migration trajectory of ponderosus photons was calculated one by one, and the distribution of photon was analyzed.RESULTS AND CONCLUSION: The decay of photo dose with depth was approximately exponential, and the second peak value will be formed at the verge of the organization. The damage of organization was a process of the threshold value. The dose curved shape was the same as the line of threshold. Using Monte Carlo method, the ransmitting law of laser in tissues of liver tumor was obtained. The results demonstrated that optimal ration of illumination intensity can obtain a shallow but entirely selective depth of tumor necrosis, but to obtain deeper tumor necrosis necessarily means some degree of normal tissue damage.

Objective To approach the clinical applied value of MSCT coronary angiography in detecting coronary artery disease. Methods 150 patients underwent MSCT coronary angiography, of them, 100 patients were also examined by coronary arteriography. The ability in showing coronary arteriae with MSCT was evaluated comparatively with coronary arteriography. Results The success-ful rate in showing coronary arteriae by MSCT was 95.3%,the excellent rate of images was 82.970%. There was negative correlation between image quality and heart rate(r=0.938). And the accurate rate in evaluating the narrowing of coronary arteriae was 91.2% with MSCT. There was no significant difference in detecting the narrowing of coronary arteriae with MSCT and coronary angiography (P>0.05). Conclusion By controlling the patients' heart rate(below 70/min) and optimizing the technical methods,MACT coro-nary angiography can detect all of the 1～3 branch of coronary artery. MSCT has some particular superiority in diagnosing coronary artery disease and evaluating the effects of coronary artery bypass graft.