1.The Effect of Yinxingdamo Injection on Changes of Serum NSE of Patients with Moderate Brain Injury
International Journal of Traditional Chinese Medicine 2008;30(3):201,204-
Objective To observe the effects of different doses of Yinxingdamo injection on changes of nerve-specific enolase (NSE) of patients with medium-sized brain injury and discusse the mechanism of Yinxingdamo injection in the treatment of brain injury. Methods The contents of serum NSE in 33 cases of craniocerebral injury were dectected by ELISA test and the results were analyzed. Results NSE levels in patients with brain injury were significantly higher than normal people (p <0.05). Yinxingdamo injection can reduce the content of NSE for brain injury patients. This reduction related with the dosage of the medicine, showing the higher the dosage is used, the greater reduction may be.Conclusion Yinxingdamo injection can reduce NSE in serum of patients with brain injury, and this may be the mechanism of Yinxingdamo injection in treating craniocerebral injury.
2.Research progress on liver regeneration after partial hepatectomy of fatty liver disease
Chinese Journal of Hepatobiliary Surgery 2015;21(5):357-360
Fatty liver disease is a kind disease characterized by liver parenchyma cell degeneration caused by a variety of metabolic abnormalities.Fatty liver disease could be considered as a risk factor for partial hepatectomy,because it can not only increase intraoperative and postoperative morbidity and mortality,but also reduce the survival rate of liver transplant recipients.Therefore,this study focuses on the impact of fatty liver disease on liver regeneration after partial hepatectomy,which could guide the clinical strategy for the implementation of liver resection.This paper overviews the recent progress on the impact of fatty liver disease on liver regeneration after partial hepatectomy and the related mechanism.
3.Determinants on aged population’s health expenditures in China
Chinese Journal of Health Policy 2015;(7):68-73
Objective:To provide references for policy-making on the establishment of a sound healthcare sys-tem for China’s aged population. Methods:Based on the framework of The Behavioral Model of Health Services Use and data from China Health and Retirement Longitudinal Study in 2011 , the Tobit model of aged population’s health expenditures is built. Results: Self-rated health conditions, chronic disease, medical insurance, endowment insur-ance, self-rated living standard, age, gender, marital status and urban-rural character are the significant determi-nants. Conclusions:The healthcare system for China’s aged population should be built through simultaneously apply-ing disease prevention and access facilitation policies and the characteristic differences of different groups of aged pop-ulation should be taken into consideration.
4.Soluble ST2 and its prospects of clinical application in cardiovascular disease
Chinese Journal of Laboratory Medicine 2014;37(12):969-972
Soluble ST2 (sST2) is a decoy receptor of IL-33 in blood.sST2and ST2L (receptor on cell membrane) seem to be markedly induced in mechanically overloaded cardiac myocytes,especially the expression of sST2.A large number of sST2 bind IL-33 thus subtracting IL-33 from the interaction with ST2L,potentially attenuating the cardioprotective effects of IL-33/ST2L pathway.Recently,sST2 has emerged as a novel for heart failure biomarker.Though sST2 was a less robust marker for the diagnosis of heart failure than NT-proBNP,it has been implicated in the prognostication of patients with acute dyspnea,acute or chronic heart failure and myocardial infarction,with particular value for mid-and long-term prognosis.However,further studies are needed in order to better point out the evidence for a routine use of sST2 evaluation in patients suffering from cardiovascular diseases.
5.itative Research of Occupational Injury Experiences of Laboratory Animal Workers
Journal of Zhejiang Chinese Medical University 2014;(8):1027-1030
Objective] To discuss the inner experiences of occupational injury of laboratory animal workers, and provide basis for conducting targeted occupational protective education and health management. [Methods] The phenomenological methodology was used in the study. 12 laboratory animal workers were participated in non-structured interview regarding the experiences of occupational injury. [Results] 3 themes were found including:category of occupational injury(physical injury, chemical injury, biological injury); emotional experiences of occupational injury(fears and concerns, helplessness and self-abasement); help most needed(more attention, knowledge supports, advanced and convenient protective equipment and hardware facilities). [Conclusion] Management of experimental animal industry should lay great emphasis on occupational health and protection of laboratory animal workers, increase both financial and material resources, and enhance occupational protection education, in order to maximize bad physical and psychological effects from occupational injury.
6.Chief Physician Ma Weiming's Experience on Treatment of Insomnia
Journal of Zhejiang Chinese Medical University 2015;(10):753-755
Objective] To explore the clinical experience of Ma Weiming in the treatment of insomnia.[Method] By following the teacher clinic, the author summarizes chief physician Ma Weiming’s academic experience of treatment of insomnia with classical prescriptions. [Results] In Ma Weiming's opinion, everything harasses the heart, mind vacillation, inducing liver ’s function of storing soul abnormal, the spirit restless is due to insomnia with much dream. So teacher Ma pays attention to “dream diagnosis”.The treatment of insomnia must be combined with heart and liver, making the mind quiet and the liver comfortable. He likes using flowers to balance Qi. In Ma Weiming's opinion, collaterals are invaded by prolonged illness, due to blood stasis. The treatment should use insect drugs to dispell wind and remove obstruction in the meridians, purifying orifices, promoting sleep. [Conclusion] According to the etiology of insomnia to distinguish among different dreams, teacher Ma uses classical prescriptions and combines with his own unique clinical experience on treating insomnia, which has significant effect and worth generalizing.
7.The feasibility of pairing general English with ESP in schools of traditional Chinese medicine
International Journal of Traditional Chinese Medicine 2015;(8):741-743
Many college students’ English is not good enough to meet the need of the society. Pairing general English with ESP is proposed so as to solve the problem. Taking college English teaching in schools of traditional Chinese medicine as a case, this paper analyzes the key factors such as teaching materials, language teachers, students, teaching objectives, methods and environment in the teaching process in order to prove that pairing general English with ESP is feasible.
8.Research of the relationship between FIB with ACS and severity of the ACS
The Journal of Practical Medicine 2015;31(14):2283-2286
Objective Serum FIB has been established as a predictor of cardiovascular events. The aim of this study was to investigate the relationship of FIB with acute coronary syndrome (ACS) and severity of the ACS. Methods A total of 692 patients with ACS who underwent a definite diagnosis were selected. Ninety-nine patients without coronary heart disease severed as control group. Detail information were recorded in age, gender, history of alcoholic, smoking, hypertension. All patients were detected in FIB and some other biochemical indicators levels. Use the correlation analysis to find the relationship of FIB with grace scoring. Results With the increase of Grace risk level and coronary artery lesions and myocardial ischemia,the levels of FIB were significantly increased (P < 0.05).The correlation analysis showed that Grace scores had a positive correlation with FIB in ACS patients. The logistic regression analysis showed the FIB was the most prominent predictors for ACS. The areas under the ROC curve of FIB were 0.87 which suggested that FIB had a higher predictive value of ACS. Conclusion The levels of serum FIB is closely related to criticality of ACS. For the ACS patients,higher levels of FIB indicated higher Grace scores. FIB level may have important clinical value in early risk stratification evaluation of prognosis and treatment options.
9.Role of liver cancer stem cells in the metastasis and recurrence of liver cancer
Chinese Journal of Digestive Surgery 2015;14(11):971-974
Liver cancer is one of the most common cancers worldwide and the third leading cause of cancer death.Partial hepatectomy and liver transplantation are the most effective therapies.However, postoperative tumor metastasis and recurrence are the main obstacles in the long-term survival.Liver cancer stem cells (LCSCs) within cancer tissues are associated with tumor occurrence, proliferation and tolerance to current therapy and are regarded as the major root of metastasis and recurrence.Eradication of LCSCs is a novel therapy of liver cancer.In this review, surface markers of LCSCs and mechanisms of pro-metastasis and recurrence, circulating LCSCs,microenvironment of LCSCs and their roles in the metastasis and relapse are summarized.
10.The early diagnostic value of serum Cys-C、β~2-MG、RBP in patients with diabetic nephropathy
International Journal of Laboratory Medicine 2010;31(2):135-136
Objective To evaluate the Cys-C、β~2-MG、RBP as marker三of early diagnosis in patients with diabetic nephropathy Ⅱ(DN).Methods ninety patients with DN were divided into three groups according to urinary albumin excretion rate (UAER),that is normal,micro and mass group.Serum Cys-C、β~2-MG、RBP、BUN,Crea were detected and parallelly contrasted in the three groups and control group with thirty healthy people.Results compared with the control group,the serum Cys-C、β~2-MG、RBP of micro and mass group both significantly increased and the normal group had no significant difference.The positive rate of Cys-C、β~2-MG,RBP in mass group was respectively 100%、100%、96.1%;the positive rate in micro group as follows:Cys C (92.3%)>B2-MG(84.6%)>RBP(66.6%)>Crea(46.1%)>BUN(28.2%).Conclusion serum Cys-C、β~2-MG、RBP have high positive rates in patients with diabetic nephropathy Ⅱ(DN).They can be used as early diagnostic marker of diabetic nephropathy Ⅱespecially Cys-C.