Objective:To elucidate the effect of osteogenic growth peptide(OGP) on proliferation and protein synthesis of human PDLCs in vitro.Methods:Human PDLCs were cultured individually in medium contained various concentrations of OGP;and cell proliferation quantity and protein synthesis were examined by MTT and coom asie brilliant blue staining.Results:In vitro,the addition of OGP in cultures resulted in an increase of cell proliferation(P

One hundred and nine cases of female isosexual precocious puberty were reported. Among them 63 cases were true precocious, while 48 pseudoprecocious. Based on the analysis of their clinical characteristics, the etiologic classification and the differentiation between true and pseudo precocious puberty were discussed. In 43 cases of true precocious puberty, Chlormadinone was used without any influence on growth. It was effective to control the menstruation and the development of secondary sexual characteristics in all but two cases who were over 8 years old. Besides, the problem of the final height of precocious girls was also discussed.

Comprehensive evaluation for colleges of stomatology is a complex systematic engineering, which is affected by the determination of index and weight. Based on the previous research results,this study establishes a comprehensive evaluation index for colleges of stomatology in China by applying Delphi method,carrying out two-round consultation to 45 experts,which includes 4 first layer indicators and 21 second layer indicators.

The plasma levels of ?-thromboglobulin (?-TG) and platelet factor 4 (PF4) and the platelet aggregation rate (PAR) were determined in the remission stage of 25 cases of chronic cor pulmonale.?-TG,?-TG/PF4,PF4,and PAR all were significantly higher in the patients with cor pul-monale than in the normal subjects (P

Objective:To evaluate the cost-effectiveness of levofloxacin and gatifoxacin in the treatment of lower respiratory tract infections.Method:The clinical data of levofloxacin and gatifoxacin in the treatment of lower respiratory tract infections were collected with the evidence-based medicine method and were evaluated with pharmacoeconomic cost-effectiveness analysis.Result:The cure rates of two drugs were 64.29%(57.70%,70.88%),and 81.43%(70.05%, 92.81%)and the cost-effectiveness ratios were 1.90 and 5.79 respectively.The?C/?E was 20.37.Conclusion:The cost-effectiveness analysis indicated that the cost-effectivenss ratio of levofloxacin is superior to that of gatifoxacin though the cure efficacy of gatifoxacin for lower respiratory tract infections is better.

Objective:To explore the influencing factors on patients' health seeking behavior in rural China by employing the theory of planned action.Methods:Data from cross-sectional household-based health survey carried out in 2008 were used in the study.Correlations between outcomes and explanatory variables were studied by Logistic regression.Results:The studying population included 19 389 adult patients over the age of 15.Illness awareness,medical experience and structural restriction factors had strong effect on whether the patients chose medical service.Pepople in different socioeconomical status suffered different influences.Conclusion:Responding to the changing trend of health service demand among rural residents,we should recognize the differentiation and allocate the healthcare resources more rationally.

AIM: To investigate the relationship between adiponectin gene SNP+45 polymorphism and coronary heart disease(CHD) in south China Han population.METHODS: The nondiabetic CHD patients diagnosed by the coronary angiography were selected as CHD subjects(153 cases),and 73 healthy adults served as normal control subjects.The polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) was performed to identify the distribution pattern of adiponectin gene SNP+45 in all subjects.The levels of plasma adiponectin were measured by ELISA.RESULTS: The frequency of T/G + G/G genotype and G allele in CHD patients were significantly higher than those in control subjects(P

OBJECTIVE:To evaluate drug utilization of inpatients in neurology department of our hospital.METHODS:Category of drugs,consumption amount,consumption sum and administration time for each person of 853 cases in neurology department of our hospital in 2008 were analyzed retrospectively.RESULTS:Of total 853 inpatients,patients with stroke accounted for 82.8%.The first 3 drugs in the list of consumption amount were Nao'an capsule,folium ginkgo tablet and Shuxuetong injection.The first 3 drugs in the list of consumption sum were Shuxuetong injection,Monosialoganglioside injection and Cobamamide for injection.Aspirin tablet,Nao'an capsule and Cobamamide for injection took up the first 3 places in the list of DDDs.CONCLUSION:Inpatients in neurology department mainly suffer from cerebrovascular disease and are treated with TCM for activating blood and eliminating stasis and nervous system agents,They are also treated various complications such as infection,constipation,hypertension,diabetes and so on.Drug use in the clinic is rational.

In recent years,cellular immune therapy represented by antigen-chimeric receptor T cells (CAR-T) has made a great breakthrough in the treatment of hematological malignancies.T memory stem cells (TSCM) and central memory T cells (TCM) can be used as most powerful carrier for T cell immunotherapy,however,how to regulate their differentiation in vitro and in vivo as well as how to construct a strong treatment system while without potential side effect become quite interesting.This article summarized the studies from the 58th America Society of Hematology Annual Meeting regarding to values and associated research progress about TsCM and TCM in hematological malignancies.

ObjectiveTo prove that grain-sized moxibustion plus Western medication is effective in preventing the attack of chronic obstructive pulmonary disease (COPD), by adopting the grain-sized moxibustion to treat patients under acute attack of COPD due to accumulation of phlegm and stasis.MethodForty patients under acute attack of COPD due to phlegm and stasis were randomized into two groups. The control group was intervened by antibiotics plus Mucosolvan and nebulization (Mucosolvan+Pulmicort+Ipratropium Bromide Solution). The treatment group was intervened by grain-sized moxibustion in addition to the above treatments.Two weeks later, the two groups were compared in the use of antibiotics, C-reactive protein, and therapeutic efficacy.ResultThe use of antibiotics and the content of C-reactive protein in the treatment group were less than that in the control group.ConclusionFor patients under the acute attack of COPD due to accumulation of phlegm and stasis, grain-sized moxibustion can shorten the time of using antibiotics and descend the content of C-reactive protein by modulating inflammation.