Sudden cardiac arrest is one of the critical clinical syndromes in emergency situations. A cardiopulmonary resuscitation (CPR) is a necessary curing means for those patients with sudden cardiac arrest. In order to simulate effectively the hemodynamic effects of human under AEI-CPR, which is active compression-decompression CPR coupled with enhanced external counter-pulsation and inspiratory impedance threshold valve, and research physiological parameters of each part of lower limbs in more detail, a CPR simulation model established by Babbs was refined. The part of lower limbs was divided into iliac, thigh and calf, which had 15 physiological parameters. Then, these 15 physiological parameters based on genetic algorithm were optimized, and ideal simulation results were obtained finally.
Algorithms ; Cardiopulmonary Resuscitation ; Death, Sudden, Cardiac ; Electric Impedance ; Hemodynamics ; Humans ; Leg ; Models, Cardiovascular

· Mesenchymal stem cells ( MSCs ) are a population of multipotent stem cells with various neurotrophins from bone marrow which are widely used in tissue, cell repair and alternative research.Recently, some researches have shown that MSCs could enhance the viability of neurons under a pathological circumstance by secreting some neurotrophins. So the neuroprotection of MSCs can provide a new method of the treatment on retinopathy that it possible to promote cells survial and functional recovery.Here we make a brief review on the secretory function of neurotrophin and neuroprotective effects of MSCs on retinal cells and its application in the treatment of retinal disease.

Humans ; Immunohistochemistry ; Lymphoma, Large B-Cell, Diffuse ; classification ; pathology

Objective We aimed to translate the English version of Patient Dignity Inventory (PDI) into Chinese and test the reliability and validity of the Chinese version of PDI in terminal stage patients.Methods Totally 285 patients in terminal stage was recruited and investigated by the Chinese version of PDI.Results The internal consistency coefficient of the Chinese version of PDI ranged from 0.728 to 0.953,which was ＞0.70; split half coefficient was 0.561; the test-retest reliability was 0.824,which showed that internal consistency of Chinese version of PDI was good.The content validity index was 0.912.Factor analysis got five factors,which explained 62.172％ of the total variance; the factor loading of each item was ＞0.4.Conclusions The Chinese version of PDI has been proved to be reliable and valid.It can be used as a valid tool for the measurement of dignity in terminal stage patients.

Objective To evaluate the clinical features of nasopharyngeal carcinoma with different sur英文摘要>=rival time and to analyze the factors associated with prognosis improvement.Methods Three hundred and fifty three patients with nasopharyngeal carcinoma treated in our hospital from January 2000 to April 2002 were analyzed retrospectively.They were divided into three groups based on their survival time.One hundred and forty five patients were divided into A groups whose overall survival time were less than five years.Sixteen patients were included in B group whose overall survival time were greater than or equal to five years and less than ten years,and the other one hundred and ninety two patients were divided into C groups whose overall survival time were greater than or equal to ten years.The clinical features were compared and factors associated with survival were identified.Results The 5 and 10 years overall survival rates of the 353 nasopharyngeal carcinoma patients underwent radiotherapy were 58.924％ and 54.391％ respectively.Curative effect of early nasopharyngeal carcinoma was better.Cox regression analysis identified age,N stage,combined with chemotherapy or not and complete remission rate of nasopharynx and neck lymph were independent prognostic factors.Conclusion For nasopharyngeal carcinoma patients,early detection,early treatment,rational comprehensive treatment and complete remission after treatment and complications prevention are important.

Orthodontics in China has experienced two important stages. At its early stage from 1950 s to 1970 s orthodontics was a division of prosthodontic department in China. There were 3 top professors in this field, who got partly training at one time or another in USA and returned to China working in Beijing Medical College, the Fourth Military Medical University and Shanghai Second Medical College. Among them, Professor Mao of Beijing Medical College was regarded as the father of Chinese Orthodontics. Removable appliance was the main tool at that stage and Prof.Mao brought forward Mao’s Classification of Malocclusion which is still used in China. The rapid developing stage began in the 1980 s when China opened its door to the world. More and more orthodontists got further training abroad and brought back advanced techniques since then. Up to now, we have already had more than one thousand of orthodontic specialists and established its own organization——the Chinese Orthodontic Society (COS), which holds domestic orthodontic meetings and organize its members to attend international meetings. Right now, almost all advanced techniques in diagnosis and treatment are adopted in China, including 3D imaging, self-ligating bracket appliance, and implant anchorage. Chinese orthodontists have started to present or publish papers in international meetings and journals and more than tiat, started to develop new app-liances, such as Driving-Force Straight Wire Appliance, which has shown advantages in treating skeletal Class Ⅲ malocclusion.

With the development of the thoracic surgery, clinicians are paying more and more attention to acute lung injury (ALI) following thoracic surgical procedures. Many factors may cause ALI during the operation. This review updates recent researches on the pathogenesis and treatment strategies of the ALI in thoracic surgical procedures.

Physiology is one of the most important elementary subjects for medical students.Associated with physiological teaching practice,some experience is shared here to further improve teaching effect.

Models of hyperthyroidism and hypothyroidism were prepared in Wistar rats by levothyroxine and tapazole respectively. The levels of blood glucose, insulin and glucose transporter 2 (GLUT2) of hepatocytic membrane were higher in mild and severe hyperthyroid rats than those in control rats (P

Memory T cells play an important role in the pathogenesis of tumors as a result of the long term of tumor immunity and the heterogeneity of T cells. Great progress in the studies on the generation, classification, mechanism of maintenance and function of memory T cells in tumor immunity have been made in recent years, which may facilitate our understanding of immunological memory and the clinical therapy of tumor.