By retrieval and analysis of literature, the origin and connotation of the word Bentai were stated. In the early twentieth century, one Japanese scholar introduced the word into acupuncture-moxibustion. It was mostly used to explore the mechanism of acupuncture-moxibustion and acupoints through scientific research. One Chinese scholar introduced the connotation into acupuncture and moxibustion in 1940, and it was mainly expressed the essence. Professor ZHU Bing systematically discussed Bentai of acupoints from a scientific point of view. The knowledge of acupoints, however, is diverse, and there is different cognition due to multiple perspectives. Acupoints may not have unique Bentai.
Acupuncture Points ; Acupuncture Therapy ; history ; History, 20th Century ; History, 21st Century ; Humans ; Moxibustion ; history ; Terminology as Topic

Objective:To study the inhibition of survivin expression by small interference RNA(siRNA) synthesized in vitro in renal cancer cell line 786-O. Methods:Three groups of survivin siRNAs were chemically synthesized in vitro and then transfected into cell line 786-O. The expression of survivin mRNA and protein after transfection were detected by reverse transcription polymerase chain reaction(RT-PCR)and Western Blotting. The proliferation of cells was detected by MTT. Results:Two sequence specific siRNAs targeting survivin down-regulated the expression of survivn mRNA and protein. The proliferation of cells was inhibited after transfection. The third one was ineffective. Conclusion:Sequence specific siRNA targeting survivin can efficiently inhibit the survivin expression and cell proliferation in renal cancer cell line 786-O. The successful application of RNAi targeting survivin might extend the list of available gene therapeutic modalities in renal cancer.

Biomarkers ; Cystatin C ; blood ; Early Diagnosis ; Hepatorenal Syndrome ; diagnosis ; Humans ; Renal Artery

AIM: To evaluate and analyze the morphological property and physiological activity of cartilaginous loose bodies in the knee joint, to research the changeable mechanism of histological morphous and physiological function. METHODS: The experiment was conducted at the Department of Pathology of the First Affiliated Hospital of Anhui Medical University, the Physical Testing & Chemical Analysis Center of Anhui Medical University, and the Electron Microscope Center of Anhui Provincial Hospital Affiliated to Anhui Medical University from January 2005 to January 2006. ①Experimental samples were 30 cartilaginous loose bodies all through arthroscopy as experimental group in which Group A (less than 6 months) had 14 samples and group B (between 6 and 12 months) 10, group C (more than 12 months) 6. Another 30 control samples were originated from non-weight loading side of articular cartilage through special equipment by arthroscopy. ②All samples were carried out the morphological measurement, light and transmission electron microscope exam, Ⅱ-collagen immunohistochemical stain, the measurement of collagen, calcium and fosforus. RESULTS: ①To compare the samples in the group A and control group, they had the identical or similar morphosis, microscopic structure of chondrocyte and distribution of extracellular matrix, the statistical treatments of the content of calcium, fosforus and collagen showed that the differences of scores between two groups were not statistically significant [calcium:(3.120?0.224),(3.090?0.231) mg/g;fosforus:(0.432?0.045),(0.455?0.067) mg/g;collagen:(462.43?17.12)(466.71?14.59) mg/g]. General speaking, comparing with the control articular cartilage, the loose bodies in group A had the normal histological property and physiological activity. ②Compared with control group, the samples in group B and C had the tendency of fibrous degeneration: necrotic or degenerative chondrocytes increasing, the contents of proteoglycan and Ⅱ-collagen decreasing, the tendency in group C more than group B, but the cartilaginous loose bodies in group B and C had many active chondrocytes mainly. Total content of collagen [(441.20?16.49),(417.33?8.38) mg/g] and Ⅱ-collagen decreased, while the contents of calcium and fosforus increased [calcium: (3.696?0.442),( 6.469?0.555) mg/g;fosforus:(0.523?0.068),(0.683?0.056) mg/g]. Generally, compared with the control articular cartilage, the histological property and physiological activity of the loose bodies in groups B and C had changed. CONCLUSION: The cartilaginous loose bodies can remain its histological property and physiological activity in the knee articular cavity for a long time, but it has the tendency of disorganization and physiological activity descending as time prolongs.

Objective To observe the effects of esophageal stricture treated with esophageal stenting.Methods 23 esophagus stenosis patients were expanded to 1 lmm,and the stent was implanted-.Results 23 patients were set into successfully,7 cases could enter the common food,11 caces could enter the soft food,5 cases could enter the semiliquid food.18 cases had the ache,6 cases had the stomach esophagus regurgitation symptom.During 1?12 month follow-up,10 cases survived,13 cases died,the cause of death was mainly later period cancer failure and metastasis.Conclusion Esophagus stenosis treatment operation was simple,safe,and the wound small,the short-term curative effect would be good.

Camptothecin/*pharmacology ; Liver Neoplasms, Experimental/*immunology ; Neoplasm Transplantation ; Sarcoma, Experimental/*immunology ; Transplantation, Isogeneic

Objective To investigate the prevalence of small intestinal bacteria overgrowth (SIBO)in patients with minimal hepatic encephalopathy (MHE). Methods Ninety patients with cirrhosis and 20 healthy volunteers were studied. All of them were assessed with glucose hydrogen breath test (GHBT) to detect SIBO. And number connection test (NCT-A, NCT-BC) and digit symbol test (DST) were used to diagnose MHE. Results One case (5.0%) out of 20 healthy volunteers was SIBO and none was MHE,and 28 cases (31.1%) out of 90 cirrhosis patients were SIBO and 38 cases (42.2%) were MHE. Twenty-one (55.3%,21/38) cases were diagnosed as SIBO among these patients with MHE,and 7 cases (13.5%,7/52)were diagnosed as SIBO among these patients without MHE. There was significant difference between cirrhosis with MHE and cirrhosis without MHE (x2 = 17.90,P＜ 0.01 ). Conclusions Patients with cirrhosis have a higher prevalence of SIBO. The incidence rate of SIBO in cirrhosis patients with MHE is more than that without MHE.

Lycobetaine ( AT-1840 ) is an effective antitumor substance. In the present work it was demonstrated that in a dose of 40 pig/kg AT-1840 could decrease the percentage of G, cells, meanwhile it increased G2 + M cells remarkably by means of flow fluocytometry method, AT-1840 could also inhibit the progression of cells from G2 to G1 phase. 8 to 72 h after, the injection the mitotic index was decreased significantly and recovered gradually in 6 d. It could inhibit the prophase and metaphase greatly, but had no marked influence on anaphase & telophase.

Long non-coding RNAs ( lncRNAs) are a class of RNA molecules which are unable to codify proteins. They express abnormally in tumor cells including prostate cancer cells and play a significant role in development of tumor. Some lncRNAs have been proven to affect physiological processes of prostate cells and act as tumor suppressor or activator and could be regulated through several methods. Thus, lncRNAs have the potential to be therapeutic targets of prostate cancer. This review introduces expressed abnormally ln-cRNAs in prostate cancer and their functions and mechanisms in prostate cancer.

In recent years,the research of pomegranate seed oil has developed and deepened, which mainly includes the study of pomegranate seed oil anti-inflammatory,antidiabetic,anti-tumor and anti-oxidation and so on.This paper has reviewed the mechanisms of its anti-inflammatory and antidiabetic functions in order to facilitate the pomegranate seed oil a better exploitation and analyzes its applicable prospects .