Periodicals as Topic

Technical standards were supports that not only for any profession’s development, but also for the basic means of modern quality control.Forensic clinical medicine has developed nearly 40 years in china, there are 23 normative technical documents at present, the range of its application has been expanding with time, the caseload has been more than 1 million pieces per year all the country. Reviewing these standards, it can be seen: Technital standard of forensic clinical medicine has absorbed a large number of advanced international ideas, assimilating plenty of practice experience at the same time, standard's system has been initially formed, it has become one of the important means to guarantee the quality of medicolegal expertise. Certainly, the construction of forensic clinical standardization in China is still an arduous task, there are also many outstanding contradiction in the existing standards, our studies on international standards were not in-depth, and so on. In the future, forensic science experts still need to strengthen the companion study of technical standards and laws or regulations, intensify tracing and evaluating of international standards in order to form more adaptive and advanced technical standards.

Burns ; Periodicals as Topic

Objective To study the expression of inducible nitric oxide synthase (iNOS),endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) in human gastric cancer and their relationship with tumor angiogenesis and to investigate the interaction of NOS and VEGF in gastric cancer.Methods The expression and distribution of VEGF, iNOS and eNOS in 34 gastric cancer specimens were detected with immunohistochemistry. Microvessel density (MVD) was counted with FⅧRAg immune specific staining.Results The expression rates of iNOS, eNOS and VEGF in 34 gastric cancers were 73.5%, 82.4%and 91.2%respectively. The expression of VEGF had a significant positive relation with iNOS, but not with eNOS. The MVDs of VEGF or iNOS positive gastric cancers were obviously higher than those of VEGF or iNOS negative gastric cancers. There was no significant difference between the MVDs of eNOS positive gastric cancers and eNOS negative ones. Conclusion MVD increases with increase of expression of VEGF and iNOS in gastric cancer. It is indicated that VEGF and iNOS can promote gastric cancer angiogenesis. VEGF and iNOS have a significant positive correlation, which suggests that in human gastric cancer, iNOS plays an important role in the production and action of VEGF.

The theory of cancer stem cells proposed that recurrence and metastasis of liver cancer are closely related to liver cancer stem cells.The traditional surgical treatment of liver cancer simply kills those rapidly proliferating tunor cells instead of eliminating hepatic cancer stem cells which play decisive role in recurrence and metastasis.As far as people have concerned,there are many signaling pathways and regulatory factors modulating liver cancer stem cells,such as the Wnt/β-catenin pathway,TGF-β pathway,Notch pathway,Hedgehog pathway,hepatitis B virus,as well as epigenetics.Further studies on regulatory mechanisms of liver cancer stem cells are of great significance,in hope of providing new evidence for treatment and prevention of recurrence and metastasis of liver cancer.

Humans ; Occupational Diseases ; prevention & control ; Occupational Health Services ; organization & administration ; Risk Assessment ; Workplace

Dendritic Cells ; pathology ; Hematologic Neoplasms ; diagnosis ; therapy ; Humans

Changes in heart rate of fetal is function regulating performance of the circulatory system and the central nervous system, it is significant to detect heart rate of fetus in perinatal fetal. This paper puts forward the fetal heart rate detection method based on short time Fourier transform and blind source separation. First of all, the mixed ECG signal was preprocessed, and then the wavelet transform technique was used to separate the fetal ECG signal with noise from mixed ECG signal, after that, the short-time Fourier transform and the blind separation were carried on it, and then calculated the correlation coefficient of it, Finally, An independent component that it has strongest correlation with the original signal was selected to make FECG peak detection and calculated the fetal instantaneous heart rate. The experimental results show that the method can improve the detection rate of the FECG peak (R), and it has high accuracy in fixing peak(R) location in the case of low signal-noise ratio.
Electrocardiography ; Fetus ; Heart Rate, Fetal ; Humans

Objective To discuss effective methods for treating hypertensive intracerebral hemorrhage at the different sites. Methods Different operative methods were adopted in 85 cases of hypertensive intracerebral hemorrhage at the different sites from January 2001 to August 2003 in this hospital. Small fenestration and hematoma clearance under local intensify anesthesia was conducted in 40 cases of hemorrhage under the cortex or in the lateral area of the basal ganglia and without brain hernia; small incision trepanation with suction and drainage of hemorrhage under local intensify anesthesia was used in 26 cases of hemorrhage in the medial area of the basal ganglia without brain hernia; craniotomy and hematoma clearance under general anesthesia was adopted in 11 cases of preoperative brain hernia and 6 cases of cerebellar hemispheric hemorrhage; lateral ventricle external drainage was adopted in 2 cases of brain stem hemorrhage involving into the fourth ventricle and also in these cases with ventricle involved. Results The overall mortality rate was 12 9% (11/85). There were no deaths in cases of hemorrhage without brain hernia,under the cortex, in the cerebellum, in the brain stem or in the lateral area of the basal ganglia.The mortality was 29 0% (9/31) in cases of hemorrhage in the medial area of the basal ganglia and 45 5% (5/11) in cases of preoperative brain hernia, respectively. Conclusions Small fenestration and hematoma clearance under local anesthesia is effective for hemorrhage under the cortex or in the lateral area of the basal ganglia and without brain hernia. Provided surgical treatment is early and adequate, the prognosis of cerebellar hemorrhage is excellent. Small incision trepanation with suction and drainage under local anesthesia exerts no appreciable effect on hemorrhage in the medial area of the basal ganglia.

Objective:To evaluate the relationship and prognostic significance of matrix metalloproteinase-9(MMP-9)、epidermal growth factor receptor(EGFR) in patients with non- small cell lung cancer(NSCLC). Methods:Immunohistochemical method (S-P) was used to detect the expression of the MMP-9、EGFR in 62 NSCLC tissues and 18 normal lung tissues. Results:The positive expression rates of MMP-9 and EGFR were 67.7%,58.1% respectively in the 62 NSCLC.Their expression levels were significantly higher than those in 18 para-cancerous normal lung tissues(P