1.Construction and application of cerebral arteriovenous malformation model in swine
Journal of Interventional Radiology 1994;0(02):-
The author described anatomical basis of areriovenous malformation model construction in swine with methods,applications and the existence of deficiency.
2.Animal Experimental Study of the National EVAL Embolic Mixture
Jiangtao WANG ; Zuoqin LIU ; Chuan LU ; Xizhong SHENG
Journal of Practical Radiology 2000;0(02):-
Objective To study the technical feasibility and embolic effect of embolism with the national ethylene-vinyl alcohol copolymer(EVAL)embolic mixture in an animal model.Methods 6 swines,25~30 kg,no matter male or female were used in this study.Superselective catheterization of ascending pharyngeal artery or rete mirable(RMB) was performed under general anaesthesia,then EVAL embolic mixture was injected to make the vascular embolism until satisfaction under fluoroscopy.The swines after embolism were followed-up 1 day,1 week,4 weeks,8 weeks,12 weeks,24 weeks and DSA,histopathological examination were respectively done.Results The embolic programes were successful in all animals,but one because of over reflux,and the embolic blood vessels could not be showed on angiography.In gross pathology,black embolic EVAL inside the vessels could be seen,which were firm and easily dissected.In histopathology,in the acute phase,all of vessel walls were destroyed in different degree,there were many neutrophils and eosinophils around the EVAL embolic mixtures and out of the vessels,and a lot of red cells could be seen,in subacute and chronic phase,mild to moderate mixed inflammatory infiltrates with histoleucocytes and large foreign-body giant cells were seen in occluded vessels.Conclusion The national EVAL embolic mixture is a suitable and easy control vascular embolic material.
3.Humanism Therapy:Realization of Ethical Spirit in Perioperative Patients
Shi YU ; Mei YIN ; Sheng TAI ; Xizhong YUE ; Yu WANG
Chinese Medical Ethics 2015;(4):581-584
This paper introduced the concept of humanistic therapy and its connotation and application in the field of surgery, the spiritual essence and the docking and bioethics.The authors also analyzed the perioperative patients need humanistic therapy, including technology, ethics, psychology, the needs of the practice; discusses the humanistic therapy in clinical practice,includes:practice conditions, personnel, measures and problems.
4.Incidence and risk factors of retinopathy of prematurity——analysis of 2185 premature infants
Qiuping LI ; Xizhong ZHOU ; Sheng ZHANG ; Junjin HUANG ; Ying CHEN ; Zizhen WANG ; Yan KE ; Zhichun FENG
Chinese Journal of Perinatal Medicine 2013;(2):71-75
Objective To determine the incidence and risk factors of retinopathy of prematurity (ROP) in preterm infants.Methods Fundus examinations were performed by RetCam Ⅱ ophthalmoscopy on 2185 premature infants (birth weight ≤ 2000 g or gestational age≤34 weeks)admitted into the neonatal intensive care unit of Beijing Bayi Children's Hospital from January 1st 2009 to December 31st 2010.According to the results,all infants were divided into ROP group and nonRO P group.Two-sample t test and Logistic regression analysis were used to investigate the risk factors of ROP.Results Among 2185 premature infants,287 (13.1 %) cases were diagnosed with RO P.According to International Classification of RO P,34 cases (11.9 %) were in zone Ⅰ,147 cases (51.2%) in zone Ⅱ,and 106 cases(36.9%) in zone Ⅲ.And there were 117 cases (40.8%) with stage 1 lesion,142 cases (49.5%) with stage 2 lesion,28 cases (9.7%) with stage 3 lesion,and no stage 4 or 5 lesion was identified.Thirty-six cases (12.5 %) were accompanied by additional diseases.Logistic analysis showed that small gestational age (OR=0.859,95%CI:0.770-0.958,P=0.006),low birth weight (OR=0.729,95%CI:0.6340.838,P=0.000),long duration of oxygen supplement (OR=2.221,95%CI:1.904-2.592,P=0.000),assistant ventilation (OR=3.104,95%CI:2.0964.956,P=0.000),apnea (OR=1.767,95%CI:1.103 2.831,P=0.018) and=anemia (OR=2.242,95%CI:1.641-3.604,P=0.000) were independent risk factors of ROP.Conclusions The incidence of ROP in premature infants is high.Small gestational age and low birth weight,long duration of oxygen supplement,assistant ventilation,apnea and anemia are risk factors of ROP.Preventive measures should be taken against these factors.