1.The value of TSGF in the changes of TACE before and after treatment in the treatment of primary hepatic carcinoma
Journal of Chinese Physician 2017;19(2):253-256
Objective To investigate the specific growth factor tumor (TSGF) in the treatment of chemoembolization (transcatheter) in the treatment of primary hepatic carcinoma (HCC) with the change of the level of arterial and transcatheter arterial chemoembolization (TACE),and the evaluation of the value in the treatment.Methods From January 2012 to December 2014 in Inner Mongolia Medical University affiliated Hospital,75 patients with primary liver cancer were treated by TACE,and all patients were treated with TACE.Then the changes of liver function,blood routine,alpha-fetoprotein (AFP),and TSGF levels were monitored at the preoperative,postoperative 1 week,1 month,and 3 months.The curative effect was evaluated.Results At 1 week after operation,aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were significantly higher than those before operation,but no differences were compared to the preoperative 1 month after operation.There was no significant difference in the level of WBC before and after operation.At 1 week after operation,the averaged AFP and TSGF water were significantly increased,but the 1 week after operation was significantly decreased.At 1 month after operation,there was no difference in the levels of TSGF and AFP between complete remission + partial remission + stable disease (CR + PR + SD) and progress disease (PD),and the levels of AFP and CR + PR + SD in PD patients were significantly lower than those in patients with TSGF at 3 months after operation.The levels of TSGF and AFP were lower in PD patients after 3 months,and there was no difference between TSGF and AFP levels at the different time after treatment in patients with CR + PR + SD.There was no significant difference in AFP levels before and after AFP treatment,and the average water level of TSGF before treatment was significantly higher than that of TACE before and after treatment.The difference was statistically significant (P < 0.05).Conclusions TSGF level in patients with primary liver cancer patients with TACE treatment increased after the first rise,especially in the treatment of 1 month after the deterioration of the situation and the tumor has a significant correlation.In the evaluation of curative effect,it has a high value.Combined with AFP,CT examination can increase the long-term efficacy of TACE treatment of primary liver cancer.
2.Feasibility for inhibiting tumor metastasis with Chinese herbal medicines as angiogenesis inhibitors
Journal of Integrative Medicine 2007;5(4):378-82
Anti-angiogenesis is one of the important ways to control tumor growth and metastasis, and searching for anti-angiogenesis herbs targeting tumor angiogenesis has become a hot topic in both basic and clinical research for tumor. Utilizing the traditional Chinese medicine theory, authors of this article discussed the feasibility and research of anti-angiogenesis effect of Chinese medicine on tumor. To develop new drugs inhibiting tumor angiogenesis from the Chinese native herbal medicine has an extremely vital significance in blocking tumor invasion and metastasis, as well as improving the patients' prognosis and their survival rates.
3.Academic ideas and clinical experience of professor JIAO Zhong-hua in treatment of cancer
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(10):-
Professor JIAO Zhong-hua engages himself in researching on treatment for oncosis and hemopathy with integration of traditional and western medicine about 40 years.In clinical treatment for oncosis and hemopathy,he emphasizes the combination of part and whole,syndrome differentiation and disease diagnosing,strengthening healthy qi and eliminating pathogens.He establishes corresponding therapeutic principles and uses tonification and attack in turn according to wane and wax beteeen healthy qi and pathogens during diseases transmutation to contain the progression of diseases.
4.CT and MRI findings of combined hepatocellular carcinoma and cholangiocarcinoma
Chinese Journal of Radiology 2012;46(8):701-704
Objective To investigate the imaging findings of combined hepatocellular carcinoma and cholangiocarcinoma(cHCC-CC) with dynamic MRI and spiral CT.Methods Twenty-three patients of cHCC-CC were evaluated.All patients had surgery and diagnoses were confirmed by histopathology.Eighteen patients had pre- and post-contrast scans with spiral CT.Five patients had MR with dynamic multi-phase contrast scanning.Imaging findings in all patients were retrospectively reviewed.Results CT of eighteen patients showed low-density masses with ill-defined margin (n =15 ),lymphadenopathy( n =5 ),invasion of blood vessels ( n =7 ),satellite lesions ( n =5 ),enhancing pseudocapsule ( n =9 ),and dilatation of intrahepatic ducts (n =1 ).MRI of five patients showed lesions with low signal on T1 WI and high signal on T2WI,lymphadenopathy(n =1 ),invasion of blood vessels (n =1 ),enhancing pseudocapsule (n =4).Dynamic CT or MRI enhanced scanning showed areas of heterogeneous enhancement in the interior or periphery of the tumor on the arterial phase,areas of inhomogeneous high signal ( corresponding regions of low signal on the arterial phase) on the portal venous phase,areas of mixed signal intensity due to retention of contrast agents on the delayed phase.Conclusions Combined hepatocellular carcinoma and cholangiocarcinom demonstrate imaging features on conventional and dynamic MRI and spiral CT,which can be helpful to improve the diagnostic accuracy of this disease.
5.Clinical characteristics and survival analysis of 368 cases of smoking lung cancer patients
Xiurong LI ; Huijie LI ; Dikui XU
Journal of International Oncology 2013;(4):309-312
Objective To discuss the clinical characteristics and the relationship with the survival of smoking lung cancer patients.Methods The clinical data of 368 cases were retrospectively analyzed by comparing the differences of the age,gender,histological type,clinical stage,treatment and tradition Chinese medicine typing,and their correlation with the survival was analyzed.Results Among the 368 patients,the ones aged between 50 to 69 accounted for 69.84% ; the proportion between the male ones and the female ones was 7.98 ∶ 1 ; the proportion of the squamous cell carcinoma was as high as 52.45% ; the proportion of the patients with small cell lung cancer in extensive stage was significantly higher than that of the patients in the limited stage(75.38% ∶ 24.62%) ; the numbers of the patients with non-small cell lung cancer in stage Ⅲ and Ⅳ was significantly higher than that in the stage Ⅰ and Ⅱ (82.77% ∶ 17.23%) ; the ones with non-surgical treatment accounted for 76.36%,and the proportion of ones with surgery treatment was 23.64% ; most of the patients were treated by both Chinese medicine and chemotherapy(41.04%) ; the main types of all patients were qi-yin deficiency syndrome and toxic heat flourishing syndrome,accounting for 36.96% and 29.28% respectively.The age (F =10.356,P =0.000),clinical stage (F =11.289,P =0.000),treatment methods (t =2.624,P =0.021),smoking index(F =3.681,P =0.021) were the key factors effecting the survival (P < 0.05),and the gender,histological type,tradition Chinese medicine type had no significant effect(P > 0.05).Conclusion The clinical characteristics of the cases are 50-69 aged,male,squamous cell carcinoma,advanced stage,treatment without surgery.The survival of smoking lung cancer patients is effected by the age,clinical stage,treatment methods and smoking index.
6.Advantage Analysis of Qilian Fuzheng Capsule in Maintenance Treatment of Advanced Non-small Cell Lung Cancer
Huijie LI ; Yuanfu QI ; Xiurong LI
Chinese Journal of Information on Traditional Chinese Medicine 2014;(3):21-23
Objective To observe the effect and analyze the advantage of Qilian Fuzheng capsule in maintenance treatment of advanced non-small cell lung cancer. Methods The advanced non-small cell lung cancer patients were randomly divided into observation group and control group, 32 cases in each group. The control group was given the best supportive care, and the observation group was given Qilian Fuzheng capsule 4 capsules three times daily additionally. The tumor control rate, quality of life, PFS and OS of the two groups were compared by follow-up. Results Qilian Fuzheng capsule maintenance treatment of advanced non-small cell lung cancer improved the quality of life. PFS of observation group and control group was 5.4 months and 4.1 months, respectively (P<0.05), and OS of the two groups was 12.3 months and 10.6 months, respectively (P>0.05). The tumor control rate of observation group was 77.42% (24/31), control group was 60.00% (18/30), with no significant difference (P>0.05). Conclusion Qilian Fuzheng capsule is a feasible application in maintenance treatment of advanced non-small cell lung cancer.
7.A STUDY ON THE CONTENT OF FATTY ACII S IN EIGHT KINDS OF COMMON SHELLFISH
Taiwu LI ; Xiurong SU ; Kun LI
Chinese Journal of Marine Drugs 1994;0(02):-
In this paper, the composition and contents of fatty acids in eight kinds of common shellfish in the Dalian Coast were studied. They were Neverita didyma and Neptunea cumingi of Gastropoda. Scapharca subcrenata, Mytilus edulis, chlamys farreri, Ruditapes philippinarum, Mactra veneriformis, Sinonovacula constrica of Lamellibranchia. Comparison with Stichopus japonicus, Penaeus orientalis, Upogebia and Portunus trituberculatus was also done. The results showed nutritive values of eight kinds of common shellfish.
8.Related factors of postpartum depression in mothers of preterm infants in neonatal intensive care unit
Cheng LI ; Xiurong YU ; Yumei WU
Chinese Journal of Practical Nursing 2015;31(16):1221-1224
Objective To assess the prevalence and related factors of postpartum depression in mothers of preterm infants in neonatal intensive care unit (NICU).Methods A total of 83 mothers who met the inclusion and exclusion criteria were investigated by using Edinburgh Postnatal Depression Scale (EPDS) and the comprehensive questionnaire for mothers of preterm infants in NICU,and the analysis was performed on SPSS 13.0 using the Spearman correlation analysis and Logistic regression analysis.Results Among the 83 mothers,38 got the EPDS score of 10 and above,which accounted for 45.78% (38/83).The disease severity (OR =3.318,P < 0.01),the worry about disease prognosis (OR =4.348,P <0.01),the worry about mental development of the newborn (OR =5.420,P < 0.01) were the risk factors for postpartum depression in mothers of preterm infants in NICU.Conclusions It's different from the correlation to postpartum depression in mothers of full-term newborns,the correlation to postpartum depression in mothers of preterm infants in NICU are closely related to premature and admission in NICU.The mothers of preterm infants in NICU are the high-risk population for postpartum depression.Routine screening mechanism for mothers of preterm infants should be established for early detection and treatment of postpartum depression,and to promote maternal and infant health.
9.Application of repetitive transcranial magnetic stimulation for motor function recovery in patients with ischemic stroke
Xiurong CHEN ; Xiaodong LI ; Guozhong ZHANG
International Journal of Cerebrovascular Diseases 2014;22(6):422-425
The excitability of cerebral cortex will change after the onset of ischemic stroke.Repetitive transcranial magnetic stimulation (rTMS) can be used to regulate the excitability in cerebral hemisphere cortex and promote the motor function recovery in patients with ischemic stroke.Studies have shown that both the affected hemisphere low-frequency rTMS and the unaffected hemisphere high-frequency rTMS can promote the motor function recovery in patients with ischemic stroke.The former may be more effective than the
10.Clinical Study of Pingyi Mixture on Resisting Tumour Transfer after Surgery
Xiurong LI ; Yuanfu QI ; Yanfeng ZHOU
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(10):-
Objective To observe the effect of Pingyi(PY) Mixture combined with chemotherapy to Ⅱ~Ⅲ patients after tumour surgery which can resist transference and recurrence of tumour.Method According to the random principle,120 patients who had suffered the surgery of commonly seen tumour were divided into observed group and matched group.Observed group adopted PY Mixture combined with chemotherapy and matched group adopted simple chemotherapy.After 3 periodic treatments,the effect of the patients after tumour surgery was observed including the ratio of recurrence and transference of observed group within 1 or 2 years,survival ratio,quality of life,body weight,immunological indexes,the toxic and sub-effect,the blood rheology behavior,and compared with simple chemotherapy.Results The ratio of recurrence and transference of observed group within 1 or 2 years was respectively 25.74% and 31.43%,which was obviously lower than that of control group,which was 32.00%,52.00%(P