1.A survey on chronic heart failure management in community physicians in Chengdu
Xiuqiong YU ; Hui JIANG ; Mei DAI ; Jiong TANG ; Lin CAI
Chinese Journal of General Practitioners 2013;12(8):634-635
A questionnaire survey on chronic heart failure management was conducted in 110 physicians from Xindu,Supo,Jiajiang and Xinhua community hospital in Chengdu from January 2007 to June 2010.Results showed that 77.3% (85/110) of community physicians lacked knowledge about prevention,diagnosis and treatment of chronic heart failure,and the diagnostic accuracy rate was only 51.3% (40/78) in these community hospitals.There was lack of awareness of the guideline of chronic heart failure:the rate of β blockers use was 15.0% (6/40) and only 5.0% (2/40) used the target dose; the rate of angiotensin converting enzyme inhibitor use was 17.5% (7/40) and only 7.50% (3/40) used the target dose.In addition,90% (99/110) of community doctors lacked the education and management for patients with heart failure.The survey suggests that the current situation of chronic heart failure management in community physicians in Chengdu is unsatisfactory.It is necessary to strengthen the training of community physicians.
2.Clinical Observation of Acupuncture at Cranial Sutures plus Rehabilitation Training for Cerebral Infarction
Guoshu WANG ; Yanping JIANG ; Wenlin YU ; Changsheng LI ; Xiuqiong YAN ; Changde YU
Shanghai Journal of Acupuncture and Moxibustion 2016;35(8):945-947
ObjectiveTo observe the clinical efficacy of acupuncture at cranial sutures (cranial acupuncture) plus rehabilitation training in treating cerebral infarction.MethodSixty patients with cerebral infarction were randomized into an acupuncture-rehabilitation group (cranial acupuncture plus rehabilitation training) and a rehabilitation group (dryrehabilitation training), 30 cases in each group, to respectively receive cranial acupuncture plus rehabilitation training and dry rehabilitation training. The Fugl-Meyer Assessment (FMA) and Barthel Index (BI) were adopted to respectively evaluate the motor function of limbs and activities of daily living (ADL); the content of hypersensitive C-reactive protein (hs-CRP) was also observed before and after treatment for the evaluation of therapeutic efficacy.ResultThe acupuncture-rehabilitation group wassuperior to the rehabilitation group in improving the motor function and ADL, and down-regulating the hs-CRP content (P<0.05).ConclusionCranial acupuncture plus rehabilitation training is the optimal protocol in treating cerebral infarction, and it canproduce a more significant efficacy than dry rehabilitation training.
3.Clinical value of vitamin D receptor gene polymorphism in lung cancer screening
Wensheng YE ; Gang CHEN ; Dehui PAN ; Yangxin CHEN ; Zhihui YU ; Jiaxiao MENG ; Xiuqiong CHEN
Chinese Journal of Primary Medicine and Pharmacy 2018;25(18):2320-2323
Objective To investigate the clinical value of vitamin D receptor ( VDR) gene polymorphism in lung cancer screening .Methods From January 2017 to September 2017 ,2000 lung cancer screening patients in the Fifth People's Hospital of Foshan were selected in the research .The VDR gene polymorphism was determined by phenol-chloroform method .DNA was extracted from the peripheral blood of patients ,different VDR genotypes [ Bsm1 bb and Bb),Apal(aa,Aa and AA)] were analyzed by univariate analysis to determine the correlation between lung cancer and VDR gene polymorphism and lung cancer incidence by multivariate non -conditional logistic regression analysis, thus to explore the relationship between different VDR genotypes and risk factors of lung cancer . Results The level of serum vitamin D in the non -lung cancer patients was (46.5 ±2.3) ng/L,which was signifi-cantly higher than (26.5 ±1.1)ng/L in the lung cancer patients (t=49.614,P=0.000).The Bsm1bp genotype, Apal aa genotype and Apal Aa genotype were the risk factors of lung cancer .The Bsm1bp and Apal Aa genotypes were independent risk factors of lung cancer .Conclusion The Bsm1 locus and Apal locus Aa genotype in VDR receptor are high risk population of lung cancer .Therefore,we should pay more attention to the clinical screening and avoid misdiagnosis and missed diagnosis .
4.Risk factors of new-onset diabetes among senior public officials in Chengdu
Hui JIANG ; Han WANG ; Xiuqiong YU ; Lin CAI ; Yuanbiao GUO ; Gang FENG ; Xiaomei WANG ; Yuan LUO ; Yuanhang HUANG ; Cong ZHAO
Chinese Journal of General Practitioners 2018;17(5):383-385
The consecutive data of 822 senior public officials in Chengdu undergoing health checkup from 2011 to 2016 were retrospectively reviewed.Among them,56 new cases of diabetes was diagnosed with a cumulative incidence of 6.81%.Fifty six age-and sex-matched healthy subjects served as controls,the risk factors of new-onset diabetes were analyzed with multivariate logistic regression.The results showed that BMI (OR =1.82,95% CI:1.27-2.59,P =0.00) and fasting plasma glucose (OR =13.63,95% CI:2.71-68.43,P =0.00) were independent risk factors of new-onset diabetes in senior public officials.
5.Five-year follow-up of ischemic cardiocerebrovascular diseases in Chengdu pediatric healthcare people
Dimao QIN ; Lin CAI ; Xiaomei WANG ; Hanxiong LIU ; Han WANG ; Xiuqiong YU ; Hui JIANG ; Feng XIONG ; Yuan LUO
Chinese Journal of Geriatric Heart Brain and Vessel Diseases 2018;20(2):168-170
Objective To study the prevalence of ischemic cardiocerebrovascular disease (ICVD) and its risk factors in Chengdu pediatric healthcare people.Methods A total of 822 pediatric healthcare people in our hospital were divided into coronary heart disease (CHD) group (n=43) and CHD-free group (n=779).Their consecutive data from 2011 to 2016 were retrospectively analyzed.The risk factors for ICVD were analyzed by multivariate regression analysis.Results CHD was detected in 523 out of 100 000 cases in 5 years and in 104 out of 100 000 cases in each year.The age was significantly older,the incidence of DM and the serum FBG and Cr levels were significantly higher in CHD group than in CHD-free group (71.26±9.61 vs 63.81±9.79,P=0.000;20.5% vs 8.2%,P=0.045;6.38±2.48 mmol/L vs 5.09±1.10 mmol/L,P=0.000;80.47± 20.87 μmol/L vs 74.81 ± 15.10 μmol/L,P =0.020).Logistic regression analysis showed that age,smoking,and serum FBG level were closely associated with ICVD (OR=1.104,95%CI:1.057-1.154,P=0.000;OR=2.219,95%CI:1.018-4.835,P=0.045;OR=1.564,95% CI:1.320-1.852,P =0.000).Conclusion The prevalence of ICVD is relatively low in pediatric healthcare people,which is closely associated with age,smoking and hyperglycemia.