1.Significance of three electrocardiographic indexes in predicting the myocardial infarct-related artery in inferior wall of acute myocardial infarction
Xiuqin CHENG ; Hanying MA ; Yujie ZHOU
Chinese Journal of Interventional Cardiology 1993;0(03):-
Objective To investigate the significance of three electrocardiographic indexes in predicting the myocardial infarct related artery (IRA) in inferior wall of acute myocardial infarction (IAMI) Methods One hundred and twenty patients with IAMI were studied Results (1) IRA was related to right coronary artery (RCA) in 98 (81 7%) case, left circumflex branch (LCX) in 22 (18 3%) cases (2) ST segment depression in lead Ⅰ identified RCA occlusion with a sensitivity of 77 6%, specificity of 90 9% in patient with IAMI, but isoelectric or elevated ST segment in lead Ⅰ identified LCX occlusion with a sensitivity of 90 9%, specificity of 77 6% (3) About QRS wave of lead aVL, S/R≥1/3 identified RCA occlusion with a higher sensitivity of 93 9% and a lower specificity of 63 6% (4) When IRA was RCA, ST segment elevated amplitude Ⅲ≥Ⅱ identified as a diagnostic index no matter the location of occlusion Conclusion Three electrocardiographic indexes have significant value in predicting the infarct related artery in inferior wall acute myocardial infarction
2.KAP-HBM-TTM (KHT)-based health management of patients with chronic diseases among community
Xiuqin WEN ; Juhong LIU ; Lingyun WANG ; Jie ZHAO ; Pengtao MA ; Jing WU ; Yu LU
Chinese Journal of Health Management 2016;10(4):291-296
Objective To explore the effectiveness of KAP-HBM-TTM(KHT)-based health management on patients with chronic diseases in community. Method From April 2014 to June 2015, 834 patients with chronic diseases living in Desheng Community were randomly sampled and assigned to the intervention group (n=423, and the control group n=411). The K-H-T mode was used for the intervention group, and the routine management mode was applied to the control group. Using self-made questionnaire we tested two groups of patients' knowledge, attitude and life-style behavior. Chi-square test was used for data analysis. Result After one year KHT-based health management, the proportion of patients with reaching the standard knowledge such as diagnosis based, risk factors, correct treatment method, life-style for prevention of chronic disease and regular check-up of the intervention group (84.9%, 88.0%, 95.2%, 89.6%, 96.9%) obviously raised compared with the control group (56.3%, 53.6%, 59.5%,55.8%, 62.7%), and the difference was statistically significant (? 2=81.270, 118.394, 155.166, 119.672, 150.173,P<0.05). The proportion of patients with reaching the standard attitude such as on the importance of chronic diseases, the family doctor service, the nurses' health management and changing risk factors of the intervention group (80.8%, 78.2%, 81.8%, 77.5%) obviously raised comapred with the control group (59.0%, 54.3%, 52.8%, 56.5%), and the difference was statistically significant (?2=46.573, 52.429, 78.435, 40.744,P<0.05). The proportion of patients with reaching the standard life-style behavior such as diet, physical exercises, psychological states, correct medication, monitoring blood pressure and glucose of the intervention group (76.7%, 72.2%, 90.6%, 99.3%, 86.1%,42.0%) obviously raised than the control group (30.9%, 30.6%, 58.0%, 73.1%, 57.5%, 28.9%), and the difference was statistically significant (? 2=174.142, 142.147, 115.318, 119.783, 83.164, 15.341,P<0.05). The rate of blood pressure and glucose control of the intervention group (84.2%, 74.8%) also improved as compared with the control group (74.3%, 60.0%), and the difference was statistically significant (? 2=11.598, 20.576,P<0.05). Conclusion KAP-HBM-TTM (KHT)-based health management was proved to be effective in the control of chronic diseases of community and improve the effectiveness of the management.
3.Significance of nonbronchial systemic artery embolization for massive hemoptysis
Shiping YU ; Ke XU ; Xitong ZHANG ; Hongshan ZHONG ; Xiuqin SU ; Jin ZHANG ; Tianyun MA
Chinese Journal of Radiology 2008;42(1):89-92
Objective To emphasize the importance of embolization of nonbronchial systemic arteries in treatment of acute and life-threatening massive hemoptysis.Methods In a series of 146 patients with hemoptysis who underwent bronchial artery embolization,we found 12 cases whose blood supply were from 17 nonbronchial systemic arteries and hemoptysis was more than 300 ml blood within 24 hours.Embolic materials included absorbable gelatin sponge(GS),kelp micro gelatin(KMG),polyvinyl alcohol(PVA) particles and metal coils. Results In the 12 cases with 17 nonbronchial systemic arteries (4 were intercostal,3 internal mammary,3 thyrocervical trunk,3 inferior phrenic,1 left gastric,2 originated from the inferior aortic arch,and 1 originated from anterior abdominal aortic wall).Five cases were embolized by GS alone,2 cases by KMG,3 cases by GS+PVA,and 2 cases by GS+PVA+metal coils.Eight cases were performed embolization once,3 cases were performed twice and 1 case was performed three times.No significant complications developed related to embolization,except that 1 patient had transient eyesight decrease after embolization of thyrocervical trunk and 2 patients had chest pain after embolization of intercostal artery which resovled without any treatment.Conclusions During bronchial artery embolization for hemoptysis patients,all supplying artery should be searched and found.Even after successful embolization of bronchial arterys for hemoptysis patients,nonbronchial systemic arterial supply should still be taken into account.
4.Discussion on occupational exposure limits of Type F uranium compounds in workplaces
Xiuqin WANG ; Zhanqi LIU ; Xia JIANG ; Yu TIAN ; Xue YANG ; Ruwei MA
Chinese Journal of Radiological Medicine and Protection 2015;35(4):290-293
Objective Derived air concentration of Type F uranium compounds are calculated respectively in order to provide reference for the management and evaluation of occupational hazard factors in workplace.Methods The air concentrations in the workplace of Type F uranium compounds were derived respectively through numerical simulationn,from individual dose limits,acute poisoning and chronic chemical damage threshold.Results Under normal operation conditions,the concentration of 5 μg /m3 for Type F uranium compounds in air of workplace can meet the requirements of radiation and chemical hazard control.Open inhalation of 1.1 mg/m3 is acceptable in a short time.Conclusions It is feasible to establish a permissible concentration limit in workplace for Type F uranium compounds.
5.Application of urine uranium monitoring in internal dose assessment
Xiuqin WANG ; Xia JIANG ; Zhanqi LIU ; Wenqing ZHANG ; Xue YANG ; Yu TIAN ; Ruwei MA
Chinese Journal of Radiological Medicine and Protection 2015;35(12):931-935
Objective To explore the applicable conditions for using urine uranium monitoring data to assess personal internal doses with a view to providing references for the occupational health management and the urine uranium monitoring in nuclear industry sector.Methods The urine uranium levels were calculated, through simulation calculation set at 1 mSv effective dose arising from either acute or chronic ingestion of uranium compounds.The results were compared with the monitoring values of workers without occupational exposure history.The feasibility of urine uranium monitoring for dose assessment of internal radiation exposure was discussed.Results For special monitoring of acute ingestion, liquid fluorimetry can meet monitoring requirements of Type F uranium compound, Type M low enriched uranium and Type S naturally occurring uranium.For routine monitoring, only Type F low enriched uranium and Type M naturally occurring uranium can be detected at shorter monitoring intervals, But it was not suitable for Type S uranium compounds.Conclusions Background levels and detection limits should be considered when urine uranium is measured for the purpose of assessment or control of exposure to uranium and the interpretation of the results.
6.Clinical analysis on coinfection in acute gastroenteritis of children
Yong ZHANG ; Zijing ZHANG ; Shaoming ZOU ; Li XIAO ; Xiuqin ZHANG ; Zhongsheng ZHU ; Yongsheng HUANG ; Zhanying MA ; Mingyan ZOU ; Qian PENG ; Yuexin ZENG
International Journal of Pediatrics 2017;44(8):570-573
Objective To investigate the incidence of enteric pathogens causing acute gastroenteritis (AGE) among children to measure the incidence of coinfections,and to compare the clinical characteristics of those infected with one versus multiple agents.Methods A retrospective study was conducted from January 2014 to December 2014.All patients between 1 month and 14 years of age admitted to the Pediatric department with a diagnosis of AGE were eligible for enrollment.Two stool samples for each patient were tested for gastrointestinal pathogens.We summarized the clinical severity of episodes,describing the duration of diarrhea,duration and frequency of vomiting,fever.All patients underwent medical evaluation with estimation of dehydration.Results One or more etiological agents were detected in 3595 out of 4728 patients(76.0%),while we did not detect any etiological agent in 1133 (24.0%).Rotavirus was detected in 1889 (40.0%),adenovirus in 412 (8.7 %),norovirus in 309 (6.5 %),verotoxigenic Escherichia coli (VTEC) in 274 (5.8 %),Salmonella spp.in 276(5.8%),Klebsiella pneumoniae in 123 (2.6%),Shigella spp.in 78 (1.6%),Staphylococcus aureus in 70 (1.5%),C.perfringens in 126(2.7%).In 1370 children out of 4728(29.0%),we found evidence of coinfection.with rotavirus and norovirus was the most common 150 (3.2%),rotavirus and C.perfringens was also common 127(2.7%).Children with coinfection had a more severe clinical presentation.The difference has statistical significance.Conclusion Rotavirus is still the most common pathogen in children with acute diarrhea,followed by NV,adenovirus,Salmonella spp.and VTEC.Rotavirus with norovirus infection was the most common.VTEC combined with three kinds of virus infection had the highest incidence.Children with multiple viral infections were more severe than those of single virus infection in the duration of vomiting and dehydration.There was no significant difference in the duration of fever and diarrhea and the frequency of diarrhea.Children infected by viruses and bacteria had a more severe clinical presentation such as fever,vomiting and diarrhea lasting for a long time,more serious diarrhea and dehydration than those with single bacteria and single virus infection.The difference has no significant difference in degree and duration of diarrhea.
7.Application of radiochemical separation and a-spectrometry in individual dose monitoring for occupational plutonium internal exposure
Xiuqin WANG ; Xia JIANG ; Wenming ZHOU ; Jingming ZHAN ; Kai YANG ; Zhanqi LIU ; Ruwei MA
Chinese Journal of Radiological Medicine and Protection 2018;38(3):205-209
Objective To explore the applicable conditions for using urine plutonium monitoring data to assess personal internal doses,in order to provide references for the occupational health management and the urine plutonium monitoring in nuclear sector.Methods Using some plutonium mixtures from DOE nuclear facilities,as an example,the urine plutonium levels were estimated through simulation calculation at 1 mSv effective dose arising from either acute or chronic inhalation of plutonium compounds,respectively.The results were compared with the typical detection limit of radiochemical separation and α-spectrometry.The feasibility of urine plutonium monitoring for dose assessment of internal radiation exposure was discussed.Results Only for type M plutonium compunds,1 mSv detection limit can be achieved using radiochemical separation and α-spectrometry within 10 d after inhalation.Conclusions Before the monitoring plan of urine plutonium is made,detection limits of monitoring method should be considered.Internal dose could be accessed using workplace air monitoring and working hours when necessary.
8. Bromadione poisoning with multiple hemorrhage after trauma as the first symptom
Yingying ZHENG ; Qiaohui LIU ; Baotian KAN ; Shuang MA ; Xiuqin LI ; Ying LIN ; Juan ZHANG ; Xiangdong JIAN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2019;37(6):464-466
Objective:
To report a case of rat poison with multiple hemorrhage after trauma.
Methods:
The clinical data of a case of rodenticide poisoning with hemorrhage as the first symptom admitted to a third-class a hospital in July 2018 were analyzed and summarized.
Results:
This patient is a rodent drug poisoning patient with hemorrhage as the first symptom.The disease was diagnosed as bromohamelin and bromadiolone poisoning through the analysis of poison detection because the rodent drug was taken in the market and the history of taking poison was concealed. The patient was given active comprehensive treatment of vitamin K1 and other drugs for clinical cure.
Conclusion
For patients with clinically unexplained hemorrhage, the possibility of rodenticide poisoning should be considered and the toxicant detection should be improved actively.
9. An incident of toadstool poisoning
Xiuqin LI ; Baotian KAN ; Xiaorong LUAN ; Yingying ZHENG ; Shuang MA ; Yin LIN ; Juan ZHANG ; Xiangdong JIAN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2018;36(12):935-937
Objective:
To investigate a poisonous mushroom poisoning incident and analyze its clinical data.
Methods:
Investigate a poisonous mushroom poisoning incident in a place in Shandong in July 2018, at the same time, the clinical data of 2 cases of mushroom poisoning were analyzed and summarized.
Results:
The incident was caused by a poisoning incident caused by residents eating poisonous mushrooms. The poisonous mushroom in this incident was identified as a scaled white goose cream. Two patients with poisoning developed gastrointestinal symptoms such as nausea and vomiting, abdominal pain and diarrhea, and liver damage occurred later. After active rescue and treatment, one patient was discharged from hospital, and the other patient developed acute pulmonary embolism during the treatment. He was discharged after interventional thrombolysis and follow-up treatment.
Conclusion
After investigation, the incident was caused by the ingestion of poisonous mushrooms mainly based on the scalloped white goose cream. After active treatment, they were cured and discharged.
10.Detection of 13 Paralytic shellfish toxins in human whole blood by high-performance liquid chromatography-tandem mass spectrometry
Xiuqin MA ; Qiang JIE ; Yujing LUAN ; Zeyu WANG ; Fanglin WANG
Chinese Journal of Forensic Medicine 2024;39(4):458-461,466
Objective To establish the analysis method of 13 Paralytic shellfish toxins(PSTs)in human whole blood by high-performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS).Methods 13 kinds of PSTs were extracted from the whole blood using acetonitrile with 1%acetate(1︰3,v︰v)solution,and separated by UPLC BEH Amide chromatographic column(100mm×2.1mm,1.7μm).The samples were detected by an electrospray ionization source(ESI)and positive and negative ion multiple reaction monitoring(MRM)mode,and quantified by matrix matching curve external standard method.Results The results showed that 13 kinds of PSTs in blood samples were linear well in the ranges of 1~100 ng/mL,with the correlation coefficient(r2)>0.995.The limit of detection(LODs)of the method were 0.5~2 ng/mL,the limit of quantitation(LOQs)were 1~4 ng/mL,and the recoveries of the method were 65.55%~114.12%.Conclusion The method is highly sensitive,reproducible,and can qualify and quantify thirteen toxins at the same time,which is suitable for the rapid detection of PSTs in whole blood samples.