Objective:To observe the clinical curative e ect of treating diarrhea-predominant irritable bowel syndrome(D-IBS) with Lichang Tang(Intestine-Regulating Decoction) and sertraline hydrochloride.Methods:72 patients with(D-IBS) was randomly divided into 2 groups:32 cases in the treatment group was given self-prescribed Lichang Tang(modi ed Tongxie Yaofang [Main recipe for painful diarrhea]+Jinlingzi San [Toosendan Powder]) and sertraline hydrochloride(50 mg,p.o.once in the early morning);35 cases in the control group were given Lichang Tang alone for oral administration.During administering these drugs,other drugs were discontinued in the 2 groups.Psychological counseling and dietary modi cation were used in all patients.The course of treatment lasted for 4 weeks.Results:The total e ective rates in the treatment group and the control group were 86.49% and 65.71% respectively,and there was signi cant di erence(P

Objective To investigate a new method to reduce air bubbles formation during drug preparation. Methods 200 portions of drugs from hospital pharmacy were randomly divided into the control group and the experimental group with 100 portions in each group. In the experimental group, the infusion bags were put flat on the desktop, the needles pierced into the bags parallel, and immersed in the liquid inside. In the control group, the infusion bags were put perpendicular to the desktop, the needle pierced into the bags vertically, the needles do not immersed in the liquid. Air bubble formation in the infusion bags was compared between the two groups. Results Air bubble formation in the experimental group was significantly less than that of the control group. Conclusions The modified new method for drug preparation can reduce the formation of air bubbles.

From typical literatures about early gastric cancer published in recent years,we review the progress of the diagnosis and treatment on early gastric cancer in order to investigate the clinical value of chromo and magnifying endoscopy etc.in early gastric cancer and the therapeutic effects of surgery,endoscopic mucosal resection and laparoscopic resection etc.in gastric cancer.

OBJECTIVE:To study the mechanism of renal toxicity of platinums in rats.METHODS:A total of 12 rats were equally assigned to receive cisplatin,carboplatin,or dicycloplatin i.v with the dosage of platinum at 10 mg?kg-1.The cumulative excretion rate of platinum in urine in 4 h and the concentration of platinum in renal tissue were measured by atom absorption method.RESULTS:The total excretion percent of platinum in urine in the first 4 h after injection of cisplatin,carboplatin,and dicycloplatin were(33.7?5.7)%,(89.1?8.5)% and(70.1?9.8)% respectively.The renal platinum concentration were 70.6?31.6,217.7?97.6,and(278.8?112.0)?g?g-1,respectively.CONCLUSIONS:Both the renal excretion speed and renal concentrations of platinum were higher for dicycloplatin and carboplatin than for cisplatin.The nephrotoxicity of platinum drugs probably has no direct relationship with the renal concentration of platinum.

In order to perfect the course-setting and enhance the teaching effect,we questioned our students' knowledge about the position and quality of medical law and the style of teaching, examining method etc. It proves that there are some differences between the fact and students'expectation on these questions.Furthermore, the author put forward some concrete advice on them in this article.

Objective To investigate the clinical effect of using warm paste during cesarean section.Methods 300 cases underwent cesarean section in obstetric department of our hospital from January to June 2013 were collected,who were randomly divided into the experimental group and the control group with 150 cases in each group.The temperature,clinical curative effect and eliminating time of shiver reaction after cesarean section of two groups were observed.Results In the observation group,there were 92 cases (61.33％) whose temperature were higher than 36℃,23 cases (15.33％) whose temperature were less than 36℃,and compared with the control group,the difference in different temperature was statistically significant.The observation of shivering patients in two groups after treatment showed that the total effective rate of the experimental group was 94.29％,while that of the control group was 76.92％.The difference was statistically significant between two groups.The difference was statistically significant in the eliminating time of shiver reaction after treatment between two groups.Conclusions Using warm paste during cesarean section is safe and effective,and can significantly reduce complications.

There are two modes of Institutional Re- view Board(IRB)review:"expedited"and"full board"or"full committee"review.The preliminary requirement of expedited review is minimal risk.Taking some interna- tional guidelines as reference,and considering the scope of review of IRB which review biomedical research involv- ing human subjects in China as well,this paper put for- ward the categories of research subject to expedited review and the operating procedure of expedited review,point out several items which should be paid attention to when con- ducting expedited review in the meantime.

Objective:To study and evaluate the protecting effect of levofloxacin hydrochloride on systemic infection in mice. Methods :960 mice were used,and divided randomly into 96 groups. Certain amount of E. coli,S. aureus,P. aeruginosa and S. flexneri were administered respectively into the mice and all of them were infected. Immediately after being infected,each group of mice were given different doses of intravenous or oral levofloxacin hydrochloride and of loxacin, in order to determine the protective effect of levofloxacin hydrochloride on the mice infected with these four bacteria. Results: The intravenous injection of ED50 of levofloxacin hydrochloride to the bacteria strains was 0.359mg/kg,5.848mg/kg,22.894mg/kg and 0. 371mg/kg respectively;and ED50through the oral route was 0. 554mg/kg,8. 129mg/kg,28. 895mg/kg and 0. 492mg/kg respectively. Conclusion :The protecting effect through intravenous injection of levofloxacin hydrochloride on systemically infected mice is more superior to that of the oral route,and also better than ofloxacin.

Vitrectomy was performed on 21 patients with ocular perforating (through-and-through) injury accompanied by intraorbital foreign body. The orbital foreign bodies in 3 cases were extracted during the operation. Functional visual success was obtained in 17 eyes (81%). Lower than 0.09 visual acuity was obtained in 8 eyes (38.1%); 0.1—0.4, in 10 eyes (47.6%); and higher than 1.0, in 1 eye (4.8%). Atrophy of the globe occurred in 2 eyes (9.5%) in which 1 eye has already been enucleated. The mean follow-up period was 12 months. The optimal operative time, the perforating injury with or without retinal detachment, and the extraction of orbital foreign body were discussed.