1.The detection value of the positive rate of MP-IgM in children with Henoch-Schonlein purpura
Chinese Journal of Primary Medicine and Pharmacy 2013;20(16):2411-2413
Objective To investigate the detection value of the positive rate of MP-IgM in children with Henoch-Schonlein purpura (HSP).Methods 80 HSP patients were chosen as the research subjects (the observation group),the other 40 healthy children were chosen as research subjects(the control group).The positive rate of MP-IgM,and positive changes in immune function of children with HSP combined with MP-IgM were analyzed in two groups.Results 32 cases were MP-IgM positive in the observation group,the positive rate was 40%.The MP-IgM positive rate in the observation group was significantly higher than that in the control group(P <0.05).The percentage of CD4+ in the observation group was significantly lower than that in the control group,the percentage of CD8+ was significantly higher than that in the control group,CD4+/CD8+ was significantly lower than that in the control group,NK was significantly lower than that in the control group(P <0.05).The percentage of CD8+ in MP-IgM positive group was significantly higher than that in the negative group,the percentage of CD4+/CD8+ was significantly lower than that in the negative group,the percentage of NK was significantly lower than that in the negative group (P < 0.05).Conclusion MP infection is an important cause of HSP,it can aggravate the immune dysfunction and play an important role in the occurrence and development of HSP.
2.Quality Control of Aseptic Materials: An Experience
Fang ZHANG ; Xiuluan ZHANG ; Ping HE ; Qiong ZHANG
Chinese Journal of Nosocomiology 1994;0(01):-
OBJECTIVE To establish the quality control system of aseptic materials in sterilization and supply department. METHODS According to Antisepsis Technic Criterion,Criterion of Check and Accept of Sterilization and Supply Department in Hospital,and Criterion of Hospital Infection newly issued by National Ministry of Health,to provide quality control of aseptic meterials in hospital. RESULTS The aseptic materials of quality control were improved,and come to being systematic standardized. CONCLUSIONS The improved quality control is an important measure for the guarantee of quality control of aseptic materials.
3.Quality Control on Whole Process in Sterilization Supply Department
Xiuluan ZHANG ; Fang ZHANG ; Guiyun YU ; Haiyan GUO ; Qiong ZHANG
Chinese Journal of Nosocomiology 2004;0(10):-
OBJECTIVE To investigate the method of quality control on the whole process in sterilization supply department. METHODS According to issued by Ministry of Health all kinds of criteria and inspections,the whole process in sterilization supply department was analyzed,and then the quality was controlled. RESULTS The whole process of sterilization was standardized,systematized and programmed. CONCLUSIONS The quality control on the whole process is an effective measure to ensure the rate of supply eligibility and support.
4.Waste Gas Discharged from Hospital Central Vacuum Aspiration System and Its Sterilization by Nanometric Photocatalysis
Zhichen ZHANG ; Xiuluan ZHANG ; Ge WANG ; Fang ZHANG
Chinese Journal of Nosocomiology 2004;0(10):-
OBJECTIVE To discuss the sterilizing effect of waste gas discharged from hospital central vacuum aspiration system. METHODS According to the characters that direct discharging these waste gases from the central vacuum aspiration system would pollute surrounding environment and that there could not be choke in the venting part of vacuum pump of this system,the method of nanometric photocatalysis was adopted to sterilize the waste gases. RESULTS The average number of colony in the engine room was 2473.67?98.23CFU/m~3 before sterilization.After 1h and 2h of sterilizing,there were 88?17.6 CFU/m~3 and 58.76 ?12.34 CFU/m~3,respectively,with significant difference. CONCLUSIONS It is effective to use the method of nanometric photocatalysis sterilizing the waste gases from the hospital central vacuum aspiration system.The rate of the sterilization is 99.99%.
5.Interaction Between Anthracene Quinone Type Anti-tumor Antibiotics and DNA
Dan SHEN ; Yanxia LU ; Xiuluan ZHANG ; Huiping SUN ; Fang ZHANG
Chinese Journal of Nosocomiology 2004;0(10):-
OBJECTIVE To study the interaction of anthracene quinone type anti-tumor antibiotics and DNA as well as the experiment method.METHODS Spectrophotometry was developed including absorption spectrum,fluorescence spectrum,electrochemical method and so on.RESULTS The union of inlay and insertion observed in ultraviolet and visible spectrophotometry usually caused hypochromic effect and red shift.Under the certain concentrations of bovin serum albumin(BSA),the endogene fluorescence intensity of BSA orderly reduced with the increase in concentration of doxorubicin(adriamycin) hydrochloride(?em 344 and the peak shape were invariable);?ex and ?em at the biggest wave length of doxorubicin were 478 and 596 nm.The fluorescence intensity was maximal of the excitation and emission spectrum when pH was 3.0.CONCLUSIONS The interaction of doxorubicin and DNA is the strongest according to the experiment and is the most widely used at present in clinics.
6.Management of Ventilator Tube System and Ventilator-associated Pneumonia
Zhichen ZHANG ; Xiuluan ZHANG ; Yuanyuan ZHANG ; Junying WANG ; Wencheng XUE ; Maorong KANG
Chinese Journal of Nosocomiology 1994;0(04):-
OBJECTIVE To analyze the relationship between the ventilator tube system and VAP.METHODS To investigate the way to use the ventilator tube system more reasonably.RESULTS To replace the ventilator tube every seven days could prevent the VAP effectively and decrease the mechanical ventilation patient′s mortality.CONCLUSIONS Decreasing the VAP incidence is a systematic and integrative work.To reinforce the management of the ventilator tube system is one of the effective methods in preventing VAP.
7.Communication in Whole-way Superior Service for Sterile Material Supply
Xiuluan ZHANG ; Baili ZHONG ; Xianping WANG ; Fang ZHANG ; Lixia YANG ; Haiyan GUO
Chinese Journal of Nosocomiology 1994;0(04):-
OBJECTIVE To establish communication and cooperation between disinfection and supply department and clinical departments in order to attain the high level of work for sterile material management and quality supervision.METHODS From Jan 2004 to Sept 2006 we sent our color printed pages about disinfection and sterilization knowledge,whole-way quality supervision,management and safety usage of sterile material to each clinical department as a manner of communication.RESULTS The communication gave a harmony of demand and supply of sterile material between them and guaranteed the whole-way superior service for sterile material supply.CONCLUSIONS The communication with whole-way quality management of sterial material supply between the disinfection and supply department and other clinical departments is very important.
8.Anti-bacterial Drugs Applying in Liver Transplanting Patients During Perioperative Period:A Survey and Analysis
Ying LIU ; Chuanhui YANG ; Xiuluan ZHANG ; Fang ZHANG ; Fang WU ; Huili HE
Chinese Journal of Nosocomiology 2006;0(12):-
OBJECTIVE To find out the situation of the application of anti-bacterial drugs in liver transplantation perioperative patients and to improve the quality of their usage.METHODS According to the criteria of DDD and DUI recommended by WHO,making a random sampling survey of the application of anti-bacterials in 206 liver transplantation perioperative patients who discharged hospital during Jan-Dec 2006,and then to analyze the rationality of their application.RESULTS Among the 206 patients,100.0% patients had received anti-bacterial drugs involving 13 kinds,137 patients in them used one,31.1% used two and 2.4% used three,and there were twelve in thirteen kinds of drugs whose DUI was no more than one.CONCLUSIONS The survey has proved that the liver transplantation perioperative patients have received rational therapy.