The heterogeneity of serum human growth hormone (hGH) in 6 normal subjects and 17 acromegalic patients before and after treatment has been studied. The results showed that "little hGH" was 34.4?10.2% and 69.8 ?13.9% of total hGH in normal subjects and in acro-megalies respectively, and that the percentage of little hGH in acromegalies increased significantly (p

The paper discusses three questions sucw as follmings: (1)the lash of market e-conomy to medical moral consciousness;(2)reasons to develop the new medical moral consciousness and behaviors;(3)reason analysis of bad medical moral consciousness and behaviors, under market economy.

Ex-PRESS miniature implantation is a new alternative of anti-glaucoma surgeries due to its advantages,such as simpler operation,similar efficacy to trabeculectomy and less complications.Could Ex-PRESS miniature implantation replace the trabeculectomy? Studies showed that Ex-PRESS implantation has more significant advantages to those patients with high risk for trabeculectomy but dose not has dominant benefits to those prone to failure of trabeculectomy from bleb scarring.The Ex-PRESS implantation requires a relative wide angle so as to have enough space to avoid the device accessing to corneal endothelium,iris or lens.So it is unsuitable for angle-closure glaucoma with higher incidence in China.In addition,the cost-effect for Ex-PRESS implantation should also be fully considered when this method could be put into practice in the near future in China.Ex-PRESS implantation seems to be unable to displace trabeculectomy.The merits and demerits for Chinese patients still need to verify by Chinese own evidence-based studies.

Objective　To observe the relationship among the degree of maturation of development of ovarian follicle and endometrial thickness and resistance index of uterine helicine arteries.Methods　Fifty six cases of normal menstrual cycle were studied by transvaginal color Doppler flow imaging.Results　Diameter of ovarian follicle increased and moved to the surface of ovary before ovulation,endometrium thickened and resistance index of uterine helicine arteries decreased.Conclusions　Observation of the development of ovarian follicle by transvaginal color Doppler flow imaging is helpful to improve regnancy rate.

BACKGROUND: Induced pluripotent stem cells are obtained from somatic cells by reprogramming method. The safety of induced pluripotent stem cells has attracted much attention because of their huge and potential value in clinical application. OBJECTIVE: To review the current studies addressing the safety and clinical application of induced pluripotent stem cells. METHODS: The PubMed database between 2006 and 2012 was retrieved by the first author to search the correlative documents concerning the safety and clinical application of induced pluripotent stem cells. Total y 203 papers were primarily gotten. Final y, 47 papers were included. RESULTS AND CONCLUSION: At present, the main methods to enhance the safety of induced pluripotent stem cells include avoiding usage of c-Myc gene, another mediate way replacing the retrovirus, direct leading of reprogramming factor protein, safer donor cells, micromolecule compound and other in-transgenosis ways. Induced pluripotent stem cells have extensive clinic treatment prospects, and can be used for the build of disease-specific induced pluripotent stem cells line.

Two hundred and thirty two patients with essential hypertension were divided into intervention and control groups (116 in each) ,by the end of study period (from January 2005 to January 2006) 106 patients in intervention group (91.4%) and 102 in control group (87.9%) completed observation.The main findings were as follows: the blood pressure control rate in intervention group was higher than that in controls (X2=23.92,P <0.01) ;the family adaptability(X2 =31.12,P <0.01),family caring(X2=37.90 ,P<0.01),family communication (X2= 17.91,P<0.01) and family function(X2 = 8.26,P<0.01)in intervention group were better improved than those in control group.The results suggest that family can be effective resources for improvement of patients with essential hypertension.

Objective To discuss the status of cesarean section in Shao Xing area, to investigate the indications of cesarean section rate and to study the possibility and feasibility for decreasing it. Methods All pregnant women and obstetricians of seven hospitals were asked to answer a designed questionaire, then the indications of cesarean section were appraised by the experts. Results The average cesarean section rate was 46.1%, the indications for cesarean section were as followed: cephalopelvic disproportion, fetal distress, social factors, proper indications for cesarean section were 74.0%. Conclusions The cesarean section rate can be decreased to 30% and less with the current standard of practice.

Objective To investigate the correlationship of second-trimester serum human chorionic gonadotropin (hCG) level and preeclampsia, premature rupture of membranes and preterm delivery. Methods 200 cases of second-trimester gestational serum hCG level was determined by radioimmunoassay,and the pregnancy outcome was followed up. Results The maternal serum hCG level in every gestative week has no significant differences;hCG level of pregnancies with preeclampsia,premature rupture membranes and preterm delivery was significantly higher than normal pregnancies. The rate of developing preeclampsia,premature rupture of membranes and preterm delivery in those hCG ≥2MOM patients (30.9%、35.8% and 14.8% respectively)was significantly higher than those MshCG

Purpose:To study the expression of Epstein-Barr virus gene BARF1 in nasopharyngeal carc inoma cells, to uncover the mechanism and effects of Epstein-Barr virus in the pathogenesis of EBV related carcinomas, and to offer some experimental supports for the prevention and treatment of EBV related carcinomas Methods :After RNA extraction from nasopharyngeal carcinoma samples, RT-PCR was con ducted to amplify the EBV gene EB virus associated nuclear antigen-1 (EBNA1) an d the new gene Bam HI A open reading frame 1 (BARF1) Then the PCR products wer e electrophoresed by 2% agarose gel and the product bands were detected and phot ographed Results:Of the 13 samples, 11 were qualified for the RNA qualit y And all of the 11 NPC cases were EBNA1 positive, showing the EB virus infect ion in the carcinoma cells 9 of the 11 cases were BARF1 positive, the positive rate was nearly 82% Conclusions:The EB virus gene BARF1 was highly expressed in the NPC samples This implies t hat apart from the latent membrane protein 1 (LMP1), BARF1 may play an important role in the pathogenesis of NPC The exact mechanisms of the BARF1 effects on the pathogenesis of NPC need to be studied further

Objective To observe and measure the Doppler sonographic features of benign and malignant ovarian neoplasms,which included morphology and hemodynamics of tumor angiogenesis,and to select the most significant features. Methods Ninety-five patients with one hundred and five ovarian tumors were examined preoperatively by power Doppler sonography to observe the morphology of tumor angiogenesis. The hemodynamic features of tumor angiogenesis referred for pulsed Doppler sonography evaluation were measured,which included peak systolic velocity(V PS ),end diastolic velocity(V ED ),mean flow velocity(V M),pulsatility index(PI),resistance index(RI) and diastolic notch. To assess the variables jointly,stepwise regression analysis was used to identify the group of features that allowed the best prediction of benignity versus malignancy. Results All Doppler features significantly associated with malignancy .The ROC curve of RI revealed that the cutoff of RI( 0.51 ) with the highest accuracy had a sensitivity of 98.0 % and specificity of 96.2 %.Conclusions RI was most significantly associated with malignancy. The combination of RI and gray-scale sonography can maximize the ability to discriminate between benign and malignant ovarian tumors.