OBJECTIVETo study the chemical constituents in Huangjuhua (flowers of Chrysanthemum morifolium).

METHODThe chemical constituents were isolated by various column chromatographic methods and structurally elucidated by NMR and MS evidences.

RESULTEleven compounds were obtained and identified as luteolin (1), quercetin (2), acacetin 7-O-beta-D-(3"-acetyl) -glucopyranoside (3), luteolin 7-O-beta-D-(6"-acetyl)-glucopyranoside (4), hesperetin 7-O-beta-D-glucopyranoside (5), acacetin 7-O-beta-D-glucopyranoside (6), diosmetin 7-O-beta-D-glucopyranoside (7), apigenin 7-O-beta-D-glucopyranoside (8), hesperidin (9), linarin (10), and luteolin 7-O-beta-D-glucopyranoside (11).

CONCLUSIONCompounds 4, 5 were isolated from the plant for the first time.

Apigenin ; chemistry ; isolation & purification ; Chrysanthemum ; chemistry ; Flavonoids ; chemistry ; isolation & purification ; Flowers ; chemistry ; Glucosides ; chemistry ; isolation & purification ; Glycosides ; chemistry ; isolation & purification ; Luteolin ; chemistry ; isolation & purification ; Nuclear Magnetic Resonance, Biomolecular ; Quercetin ; chemistry ; isolation & purification