1.A clinical comparative study of treatment effect of adrenal pheochromocytoma between laparoscopic and open surgery
Chinese Journal of Postgraduates of Medicine 2013;36(26):18-21
Objective To investigate the treatment effect of adrenal pheochromocytoma between laparoscopic and open surgery.Methods Sixty cases diagnosed as adrenal pheochromocytoma undergoing surgery,were grouped by different surgical methods,32 cases with laparoscopic surgery as the laparoscopic group,28 cases with open surgery as the open group.Comparing two groups with the curative effect.Results Postoperative pathology confirmed the diagnosis with pheochromocytoma,5 cases with infringe upon the envelope,laparoscopic group had no transfer laparotomy.Intraoperative systolic breadth,operative time,intraoperative blood loss,intraoperative blood transfusion volume,length of incision,postoperative drainage time,postoperative drainage and postoperative hospitalization days in open group were (25.21 ± 9.42) mm Hg(1 mm Hg =0.133 kPa),(127.38 ± 16.40) min,(420.48 ± 185.62) ml,(238.20 ± 68.39) ml,(13.23 ± 1.14) cm、(7.26 ± 1.20) d,(326.50 ±96.48) ml,(9.31 ± 1.89) d,in laparoscopic group were (10.42 ± 8.89) mm Hg,(76.29 ±24.61) min,(120.54 ±104.28) ml,(86.49 ±36.53) ml,(8.44 ±1.03) cm,(5.47 ± 1.55) d,(180.32 ± 100.52) ml,(7.21 ± 1.30) d,differences between two groups were statistically significant (P <0.05).There was no significant difference in maximum tumor diameter,complication incidence,recurrence rate between open group and laparoscopic group (P > 0.05).Conclusions Laparoscopic and open surgery treatment of adrenal pheochromocytoma curative effect is good,high security,laparoscopic surgery in patients with traumatic small relative to restore,no contraindications to laparoscopic treatment in patients with laparoscopic surgery treatment can be preferred.
2.Therapeutic effect of minimally invasive percutaneous nephrostolithotomy in treatment of kidney calculi and influence of renal function
Xishe LIU ; Jianhua LI ; Kui ZHANG
Chinese Journal of Postgraduates of Medicine 2013;(11):31-34
Objective To investigate the therapeutic effect of minimally invasive percutaneous nephrostolithotomy (mPCNL) in treatment of kidney calculi and the influence of renal function.Methods According to the operation method,70 patients with kidney calculi were divided into mPCNL group (38 patients) and percutaneous nephrostolithotomy (PCNL) group (32 patients).The curative effect,serum creatinine (SCr) and blood urea nitrogen (BUN) postoperative 1 month were compared.Results The patients in two groups were successfully for broken calculi.The operation time of stag-horn calculi,retinitis simplex kidney pelvis calculi and kidney calices multiple calculi in PCNL group were significantly shorter than those in mPCNL group [(89.13 ± 13.36) min vs.(112.32 ± 12.41) min,(65.28 ±9.76) min vs.(78.84 ± 12.03) min,(98.97 ± 11.84) min vs.(112.64 ± 10.87) min,P < 0.05].The first stage clearance rate of retinitis simplex kidney pelvis calculi in PCNL group was significantly higher than that in mPCNL group [88.89%(8/9) vs.57.14%(8/14),P < 0.05].But the clearance rate of kidney calices multiple calculi in PCNL group was significantly lower than that in mPCNL group [58.33%(7/12) vs.86.67%(13/15),P<0.05].The first stage clearance rate of stag-horn calculi in two groups had no significant difference [63.64%(7/11) vs.66.67% (6/9),P > 0.05].The patients in two groups had no serious complication.The rate of fever after operation in two groups had no significant difference [15.63% (5/32) vs.10.53% (4/38),P > 0.05].The level of SCr and BUN in the patients combined with kidney insufficiency in two groups were decreased slightly (P > 0.05).The improvement rate of renal function in two groups had no significant difference (P >0.05).Conclusions mPCNL and standard channel PCNL in treatment of kidney calculi can achieve a good first stage clearance rate,and the incidence rate of postoperative complication is lower.mPCNL and standard channel PCNL have no obviously influence on early stage renal function.The operation time of mPCNL is generally longer,but the therapeutic effect of kidney calices multiple calculi is better than standard channel PCNL.