1.Relationship between intraocular pressure and central corneal thickness in healthy people undergoing health check?ups
Chinese Journal of Health Management 2019;13(4):325-329
Objective To investigate the distribution of intraocular pressure (IOP) and its relationship with central corneal thickness (CCT) in healthy people. Methods Participants included 1 715 persons undergoing health check‐up during January 1 to December 31, 2018. They were enrolled according to the randomized digital table into this investigation by simple random sampling method; 879(51%) persons were male with an average age of 48.0±13.6 and 836 (49%) persons were female with an average age of 48.0±12.7. Participants were divided into different groups according to ten‐year intervals. Each personal data, IOP and CCT were obtained; IOP was obtained by non‐contact tonometer and CCT was obtained by optic coherence tomography. The data were analyzed by SPSS 25 statistical software. Results The average IOP in this study was 15.04± 3.08 mmHg (1mmHg=0.133kPa) and the average CCT was 535.01±31.76 μm. The average IOP of each group showed an increase with age, and in the 50‐59 years group it reached the highest level (15.47±3.11 mmHg), after which, it decreased again. The average CCT values in all groups decreased with ageing and the highest level was in the 18‐30 years group (540±32.68 μm). The average IOP and CCT in males was higher than that in females. Multiple regression analysis adjusted for potential confounders such as age and gender implied that CCT is positively related to IOP (P<0.01). The IOP appeared to increase by 0.044 mmHg with the increase of every 1 mm of CCT (95% CI: 0.040~0.048, P<0.01). Conclusion IOP is closely related to CCT. More attention should be paid to CCT during the measurement of IOP to avoid misjudgment of a higher IOP for a higher CCT value as a pathological IOP or a pathological IOP among normal statistical range as a normal one, otherwise an opportunity for good treatment may be lost.
2.Effect Evaluation of Multidisciplinary Collaborative Diagnosis and Treatment Model for Children with Brain Injury
Xiongwu YU ; Yunli ZHOU ; Zhiyong DING ; Chaohong WANG ; Zeyi XIE ; Hongna LU ; Hua JIN
Journal of Kunming Medical University 2024;45(1):156-162
Objective To summarize the experience of multi-disciplinary team(MDT)in the pediatric department of Qujing Maternal and Child Health Hospital,and to evaluate the effectiveness of MDT on neonatal brain injury.Methods The clinical data of children with brain injury and treated in the pediatrics department of Qujing Maternal and Child Health Hospital from November 2019 to April 2023 were collected.The children with brain injury and treated from October 2019 to June 2020 were regarded as the non-MDT group,and the children with brain injury and treated from July 2020 to April 2023 were regarded as the MDT group for comparative analysis.Chi-square test/t-test was used to compare and analyze the clinical data of the two groups.Results Among the 890 cases of pediatric brain injury,there were 519 males and 371 females.The median and quartiles of the age distribution for the two groups were as follows:MDT group 2.00(0.82,5.00)years and non-MDT group 1.00(1.00,4.00)years.Craniocerebral injury was the main type of brain injury in both groups,in addition,among children with craniocerebral injury and intracranial hemorrhage,the cure rate of MDT group was higher than that of non-MDT group,and the difference was statistically significant(P<0.05).Among the 405 children in MDT group,154(38.0%)underwent the surgery,while among the 485 children in non-MDT group,121(24.9%)underwent the surgery.The difference was statistically significant(P<0.05).23.2% of children in MDT group were in critical condition during the hospitalization,which was significantly lower than that in non-MDT group(30.5%),and the difference was statistically significant(P<0.05).The unhealed rate of MDT group(2.0%)was also significantly lower than that of non-MDT group(5.6%),the cure rate of MDT group(40.5%)was significantly higher than that of non-MDT group(34.4%),and there was a statistically significant difference(P<0.05).The expense of treatment,medicine and sanitary materials in MDT group were lower than those in non-MDT group,and the differences were statistically significant(P<0.05).The multivariate Logistic regression model analysis of the cure rate of children with brain injury showed that the MDT model could effectively improve the cure rate of children with brain injury(RR = 1.513,95% CI = 1.134-2.020).The results of multiple linear regression model analysis showed that there was no statistical difference in the effect of MDT on the actual hospitalization days of children(P>0.05).Conclusion Using MDT model to diagnose and treat children with brain injury is helpful to improve the cure rate,reduce the risk of children's disease aggravation,and achieve the significant therapeutic effects in children with brain injury.MDT model is worth popularizing and applying in children with brain injury.