BACKGROUND:Bal oon kyphoplasty is a new technique of microtraumatic surgery of spine developed in recent years, and brings a new pathway for the treatment of osteoporotic vertebral fracture in the elderly.
OBJECTIVE:To investigate the therapeutic effect of percutaneous bal oon kyphoplasty on osteoporotic vertebral fracture, and to explore the main point of injecting bone cement.
METHODS:A total of 22 patients with osteoporotic vertebral fracture at the age of 60-78 years underwent percutaneous bal oon kyphoplasty under C-arm fluoroscopy. In accordance with the standards of WHO, antalgic effects were evaluated. The injection time, manner and dose of bone cement were analyzed.
RESULTS AND CONCLUSION:Al patients were fol owed up for 1-12 months. Postoperative pain was completely lessened in 15 patients, and partial y relieved in 7 cases, with an effective rate of 100%. Spinal mobility increased. No incision surgery was needed in al patients. No complications such as pulmonary embolism or nerve injury appeared. These results indicate that percutaneous bal oon kyphoplasty for treatment of osteoporotic vertebral fractures is minimal y invasive and simple, has less complication and effectively reconstructs vertebral body strength, and can better al eviate the pain, is an effective minimal y invasive spinal treatment technology. To strictly understand the main treatment point can obtain satisfactory clinical curative effects, including precise diagnosis of the disease, identification whether patient’s pain is induced by fractures, preoperative intraoperative exact localization of the affected vertebra, perfect puncturing technique, suitable postoperative treatment and nursing. It is also important to strictly master the time of injecting bone cement and the dose of bone cement. Bone cement injection was commonly done in drawing-wire stage. Too early injection easily induced leakage and toxic reaction. Too late injection affected the expansion of bone cement and therapeutic effects. The injection of bone cement should be finished under a perspective environment, which can effectively avoid bone cement leakage.

BACKGROUND:Since percutaneous injection of bone cement vertebroplasty has been successful y used in treatment of spine fracture, percutaneous vertebroplasty is trying to be utilized in the treatment of vertebral hemangiomas.
OBJECTIVE:To evaluate the safety and effectiveness of percutaneous injection of bone cement vertebroplasty in the treatment of symptomatic vertebral hemangiomas.
METHODS:Total y nine patients with symptomatic thoracic vertebral hemangioma patients, including two males and seven females, had back pain. Of them, two cases suffered from nerve root irritation. Percutaneous vertebroplasty with bone cement was used alone. Postoperative clinical and radiographic fol ow-up was conducted.
RESULTS AND CONCLUSION:The success rate was 100%, and no pulmonary embolism or nerve injury appeared. Postoperative imaging showed no leakage of spinal canal or foramen. At 24 hours after treatment, the symptoms had eased;nine cases were fol owed up for 3 to 36 months, showing that the original symptoms and signs disappeared or almost disappeared, no recurrence of vascular tumors. Results indicated that the percutaneous injection of bone cement vertebroplasty for the treatment of symptomatic vertebral hemangiomas is a safe and effective treatment;it can not only relieve symptoms, but also can increase the stability of the vertebral body, and prevent compression fracture and recurrence.

Objective: To observe clinical therapeutic effective of 5 mono nitre isosorbide combined with ginkgo leaf in the treatment of angina pectoris. Methods:100 cases of angina pectoris were randomly divided into control group (5 mono nitre isosorbide) and treated group (5 mononitre isosorbide combined with ginkgo leaf). The therapeutic course lasted four monthes. Results: Nitroglycerin consumption in treated group was lower significantly than that in control group. The effective rate was 94.8% in the treated group and 84.2% in the control group after four monthes ( P

Objective To explore the clinical efficacy of Chinese traditional medicine combined with western medicine in the treatment of cirrhosis with ascites and hypoalbuminemia. Methods The trial group was treated with Chinese traditional medicine (modified decoction for Zhongman Fenxiao) combined with western medicine (drugs for protecting liver, diuretis, etc.). The control group was simply treated with Western medicine. Results After 4 weeks of treatment, the cure rate of the trial group was 43.75% and the total effective rate was 87.50%, significantly higher than that of the control group with 30.00% and 80.00%, respectively (P 0.05). The liver function in the control group was greatly decreased than that in the trial group (P

Objective The aim of this study was to investigate the relationship of gastric mucosal lesions and the parietal oxyntic function in rats under stress as a result of seawater-immersion after open abdominal injury. Methods Thirty-two SD rats were subjected to open abdominal injury followed by seawater immersion. The animals were randomly divided into four groups: control, 1h, 2h, 3h stress for 1h, 2h, and 3h groups. The pH value of gastric juice and gastric mucosal ulcer index (UI) were measured. The gastric mucosal lesions were observed with light microscopy, and the ultrastructural changes in parietal cells were observed by transmission electron microscopy. Results There was a significantly negative relationship between UI and pH value (r=-0.70,P

ObjectiveTo observe the curative effect of lumbar traction and Huantiao point-injection in the same side on lower limb pain induced by prolapse of lumbar intervertebral disc.Methods86 patients with lower limb pain induced by prolapse of lumbar intervertebral disc were randomly divided into the treatment group and control group with 43 cases in each group. Patients of the treatment group were treated by Huantiao point-injection in the same side and lumbar traction, and cases of the control group were treated by lumbar traction only.ResultsThe recovery rate of the treatment group was higher than that of the control group (P<0.01) after 3 weeks treatment.ConclusionThe effect of lumbar traction and Huantiao point-injection in the same side on lower limb pain induced by prolapse of lumbar intervertebral disc is better than lumbar traction only.

Objective To explore the difference of serum oxytocin levels between autistic children and healthy children at the age of 3-5,and the relationship between serum oxytocin levels and social competence in children with autism.Methods Twenty-five autistic children and twenty healthy children were tested by an enzyme-linked immunosorbent assay to evaluate the oxytocin levels;the SRS was used to evaluate social competence of children with autism.Results Mann-Whitney test showed there were significantly differences in oxytocin level between autistic children and healthy children(P<0.05).The social competence of autistic children was negatively correlated to oxytocin levels(r=-0.735,P<0.01).Multiple liner regression analyses showed that oxytocin level was an impact factor of the social competence of autistic children(F=11.931,P<0.01).Conclusion This study indicates that the serum oxytocin level maybe a factor which influence the social competence of autistic children.

Objective:To evaluate the immunogenicity of an experimental SARS-CoV inactivated vaccine.Methods:The virus suspension of F69 strain was inactivated with 0.4% formaldehyde and purified,then used as the immune antigen combined with Freund′s adjuvant.Eight adult New Zealand rabbits were immunized 4 times with this vaccine.12 sets of rabbit serum were sampled from the third day to 74th day after first immunization.Titers of specific IgG antibody and neutralizing antibody were determined by indirect ELISA and micro-cytopathic effect neutralizing test.Results:Rapid and potent humoral immune responses were induced by F69 inactivated vaccine in all eight immunized rabbits.Both specific IgG antibody and neutralizing antibody all peaked just with 2 vaccinations,with the maximum titer of 1∶81 920 and 1∶20 480 respectively about 6 weeks after first immunization.Across neutralizing reaction existed between F69 and Z2-Y3 strains.Conclusion:F69 inactivated vaccine owns strong immunogenicity.Similar antigenic epitopes exist between the F69 strain and Z2-Y3 strain,which ensured the cross neutralizing reaction.

Objective To evaluate the safety and efficacy of the endovascular treatment of anterior circulation multiple occlusions (AMO) in acute ischemic stroke.Methods The clinical data of 10 patients with AMO treated by endovascular method from January 2011 to August 2013 were retrospectively analyzed.The proximal internal carotid artery (ICA) occlusion was treated using angioplasty in order to achieve ideal location of the guiding catheter.When necessary,stenting was performed after the reconstitution of the intracranial vessel.Recanalization was assessed according to the thrombolysis in cerebral ischemia (TICI) grade.Clinical prognosis was assessed using mRS at 3 months.The National Institutes of Health Stroke Scale (NIHSS) on admission and at discharge was compared using t test.Results The intracranial vessel was recanalized successfully (TICI ≥ 2b) in 9 cases and cervical carotid was stented in 8 cases.Adverse events were recorded in 3 patients,including one case of asymptomatic subarachnoid hemorrhage and two cases of symptomatic intra-cerebral hemorrhage.Mortality rate was 10 ％ (n=1).At the three-month follow up,mRS ≤ 2 was observed in five patients.The mean NIHSS scores was 15.7±2.2 on admission and 9.6±4.7at discharge,and the difference was statistic significant(t=2.86,P=0.02).Conclusion Endovascular therapy of AMO is technically feasible,and relatively safe and effective.

Objective To explore the serum levels of brain-derived neurotrophic factor in patients with depression and their correlation with age,gender,age of onset,illness course,depressive severity.Methods Serum BDNF levels in 91 depressive patients and 36 healthy controls were assayed by the ELISA method .The clinical char-acteristics were assessed by the Hamilton Rating Scale for Depression ( HAMD) .Results The serum BDNF levels in depressive patients were (24.38 ±6.27)μg/L,which was significantly lower than (31.44 ±10.72)μg/L in controls (t=3.708,P <0.01) and were unrelated to age,gender,age of onset,illness course,depressive severity (r =-0.034,t=0.068,r =-0.025,0.026, -0.076,P >0.05).Conclusion Serum BDNF levels in depressive patients was decreased and low levels of BDNF in serum may be a state characteristic for depression .