Objective To explore the clinical efficacy of Chinese traditional medicine combined with western medicine in the treatment of cirrhosis with ascites and hypoalbuminemia. Methods The trial group was treated with Chinese traditional medicine (modified decoction for Zhongman Fenxiao) combined with western medicine (drugs for protecting liver, diuretis, etc.). The control group was simply treated with Western medicine. Results After 4 weeks of treatment, the cure rate of the trial group was 43.75% and the total effective rate was 87.50%, significantly higher than that of the control group with 30.00% and 80.00%, respectively (P 0.05). The liver function in the control group was greatly decreased than that in the trial group (P

ObjectiveTo observe the curative effect of lumbar traction and Huantiao point-injection in the same side on lower limb pain induced by prolapse of lumbar intervertebral disc.Methods86 patients with lower limb pain induced by prolapse of lumbar intervertebral disc were randomly divided into the treatment group and control group with 43 cases in each group. Patients of the treatment group were treated by Huantiao point-injection in the same side and lumbar traction, and cases of the control group were treated by lumbar traction only.ResultsThe recovery rate of the treatment group was higher than that of the control group (P<0.01) after 3 weeks treatment.ConclusionThe effect of lumbar traction and Huantiao point-injection in the same side on lower limb pain induced by prolapse of lumbar intervertebral disc is better than lumbar traction only.

AIM:To observe the dynamic changes of neurokinin A(NKA) and calcitonin gene-related peptide(CGRP) levels in gastric mucosal and plasma in rats after abdominal seawater-immersing trauma,and to investigate the influence of these two sensory neuropeptides on acute gastric mucosal lesion.METHODS:Thirty-two SD rats were randomly divided into four groups(normal group,celiac seawater-immersing trauma 1,2 and 3 h groups).With emzyoimmunoassay and radioimmunoassay respectively,gastric mucosal and plasma NKA and CGRP levels in rats were measured.RESULTS:Compared with normal rats,with the seawater-immersing time prolonged,gastric mucosal NKA and CGRP levels in rats were progressively decreased(P

Objective To explore the value of an advanced reciprocating gait orthosis (ARGO) combined with comprehensive rehabilitation treatment in rehabliltating complete spinal cord injury (SCI) patients. Methods Twelve patients with complete SCI at the T4~L2 level were fitted with an ARGO. Before and after fitting the ARGO,comprehensive rehabilitative excecises were conducted. After training, ambulation was evaluated, and competence in the activities of daily living was evaluated using the Barthel index and Functional Independence Measure. Results The patients' ambulation improved markedly after fitting the ARGO and training. Barthel index and FIM scres improved significantly. All 12 patients achieved therapeutic or functional ambulation. Conclusion With the aid of an ARGO, patients suffering from complete SCI below the T4 level can achieve functional walking and improve their quality of life.

Objective To investigate the optimal workflow and protocol for integrated PET/MR by comparison with PET/CT.Methods A total of 228 patients were enrolled in this study for PET/CT and PET/MR evaluation on the same day.Six PET/MR protocols with different MR sequences but the same PET acquisition protocol were investigated and the optimal protocol was identified based on image quality,acquisition time and diagnostic performance.Results PET/MR workflow was similar to PET/CT,however,some special issues needed to be considered for PET/MR.Among the 6 protocols,protocol No.6 outperformed others for body and head regions.Types of artifacts were found more often in PET/MR than in PET/CT.Conclusions By optimizing the protocol,PET/MR could achieve almost the same diagnostic performance as PET/CT.However,the issues of long acquisition time and artifacts on PET/MR need to be further improved.

Objective:To investigate the efficacy of floating acupuncture therapy in the treatment of chronic refractory pressure ulcers and its effects on serum levels of superoxide dismutase, malondialdehyde and insulin-like growth factor-1.Methods:A total of 60 patients with chronic refractory pressure ulcers who received treatment in The Second Hospital of Jiaxing from October 2019 to October 2021 were included in this study. They were randomly divided into observation and control groups, with 30 patients in each group. The patients in the control group were given routine treatment, while the patients in the observation group were given floating acupuncture therapy based on routine treatment. Clinical efficacy, wound healing rate after 7, 14 and 21 days of treatment, the time of emerging granulation tissue, the time of shedding rotten meat, and the time of wound healing, changes in serum levels of superoxide dismutase, malondialdehyde and insulin-like growth factor-1 after 21 days of treatment relative to those before treatment were compared between the two groups.Results:Total response rate in the observation group was significantly higher than that in the control group [90.0% (27/30) vs. 66.7% (20/30), χ2 = 4.81, P < 0.05]. Wound healing rate after 7, 14 and 21 days of treatment in the observation group was significantly higher than that in the control group ( t = -5.45, -7.77, -7.51, all P < 0.001). The time of emerging granulation tissue, the time of shedding rotten meat, and the time of wound healing in the observation group were significantly shorter than those in the control group ( t = 5.69, 9.26, 8.91, all P < 0.001). After 21 days of treatment, serum levels of superoxide dismutase, malondialdehyde and insulin-like growth factor-1 in the observation group were (96.52 ± 10.43) U/mL, (4.32 ± 0.78) μmol/L, (43.52 ± 8.29) μg/L, respectively, which were significantly different from (83.76 ± 6.81) U/mL, (5.48 ± 0.92) μmol/L, (36.78 ± 9.18) ng/mL, in the control group ( t = 5.61, 5.27, 2.98, all P < 0.05). Conclusion:Floating acupuncture therapy is effective in the treatment of refractory pressure ulcer. It can accelerate wound healing, increase serum superoxide dismutase and insulin-like growth factor-1 levels, and decrease serum malondialdehyde level.

OBJECTIVETo assess the role of oxidative metabolism and nitric oxide synthesis for elucidating their pathophysiological mechanisms in a Tibetan patient with essential hypertension.

METHODSThe serum levels of total superoxide dismutase (T-SOD), malondialdehyde (MDA), total antioxidant capacity (T-AOC), nitric oxide (NO) and nitric oxide synthase (NOS) were assayed in sixty native Tibetans (thirty hypertensive patients and thirty healthy volunteers as control).

RESULTSThe levels of T-SOD, T-AOC, NO and NOS were significantly lower in the patient group than in the control group (P < 0.01); MDA was significantly higher in the patient group than in the control group (P < 0.01). The level of MDA had a strong negative correlation with T-SOD, T-AOC, NO and NOS (r = -0.82, -0.76, -0.79, -0.73, respectively, P < 0.001 for all).

CONCLUSIONTibetan patients with essential hypertension (EH) may have underlying oxidative metabolism dysfunction and depressed NO synthesis, both responsible for the hypertensive process.

Adult ; Altitude ; Endothelium, Vascular ; physiology ; Female ; Humans ; Hypertension ; etiology ; Male ; Middle Aged ; Nitric Oxide ; biosynthesis ; Oxidation-Reduction ; Tibet