Objective To study the effect of Lamivudine therapy in preventing disease progression in patients with the chronic serious hepatitis B during the short-term. Methods 40 patients with the chronic serious hepatitis B, who have the trend of developing severe hepatitis,were randomized into treating group(n=20) and control group (n=20).The two groups were given the same synthetic treatment. Treating group was given Iamivudine 100mg daily in addition, for 8 weeks. Effects were assessed by clinical , biochemical , the incidence of chronic severe hepatitis,suvival rates and virologic parameters. Results (1) After 8-weeks treatment , the incidence of chronic severe hepatitis in treating group was lower than in control group(X~2=4. S1 ,P

Although the symptom of stable bronchiectasis is not significant, the four pathological factors including qi stagnation, sputum obstruction, blood stasis and lung-spleen qi vacuity still exist inside patients' bodies, making them in the state of both healthy and ill. This article discussed the application of the idea of preventive treatment to intervene and treat, which could prevent the emergence of new diseases and the changing of existing diseases. It could prevent vacuity evil and bandit wind, depressed qi transforming into fire, phlegm depressed in the lung and channel obstruction caused by long-term diseases. It can effectively prevent the acute attack of bronchiectasis and improve the patients' lung function and life quality.

Bile dut injury (BDI) is one of the severe complications of laparoscopic cholecystectomy (LC).The classification,diagnosis and treatment of the BDI caused by LC are partly controversial.The most efficient classification of the BDI is Strasberg-Bismuth's classification and the three modes and four classes developed by the Biliary Surgery Group of Surgery Branch of Chinese Medical Association.Although the success rate of intraoperative diagnosis for the BDI is very low,in most cases,the BDI is diagnosed by clinical manifestations and assistant examinations.Accurate classification and early diagnosis could help us to make a specific one for each patient according to certain situation.In this review,we focus on the classification,diagnosis and treatment of the BDI caused by LC.

BACKGROUND:The appropriate choice of orthoses based on hemiplegic patient’s condition can improve motor function recovery in stroke patients.
OBJECTIVE:To review the motor function recovery of stroke patients with hemiplegia wearing different types of orthoses.
METHODS:Application of different types of orthoses in hemiplegic patients was reviewed through access to literature, as wel as effects of a variety of orthoses on the recovery of motor functions in hemiplegic patients.
RESULTS AND CONCLUSION:Orthoses can reduce limb muscle tension and muscle spasms, and improve motor function and overal daily living skil s in stroke patients with hemiplegia, which play a variety of roles, including stable support, fixed protection, correction of deformity and functional compensation. However, the long-term therapeutic effect of orthoses cannot be verified because of fewer cases, shorter time for therapeutic observation, and the lack of long-term fol ow-up. It is necessary to perform long-term fol ow-up for the verification of long-term efficacy of orthoses. Meanwhile, the appropriate timing for removal of orthoses needs further study.

BACKGROUND:Stem cells under appropriate conditions can be induced to differentiate into neuron-like cells. Chinese herbs can function in cellproliferation and differentiation.
OBJECTIVE:To investigate the interventional effects of traditional Chinese medicine on stem celltransplantation in the treatment of cerebrovascular diseases.
METHODS:Experimental studies concerning traditional Chinese medicine intervention for stem celltransplantation were retrieved and analyzed. Under specific conditions, stem cells can proliferate in vitro in a suspended or monolayer manner, and can be potential y induced to differentiate into neurons, oligodendrocytes and astrocytes, thereby providing basis for stem celltransplantation in the treatment of cerebrovascular diseases. We observed expressions of nestin, glial fibril ary acidic protein, and microtubule-associated protein expression for analysis of stem cellproliferation and differentiation.
RESULTS AND CONCLUSION:Baicalin or Astragalus saponin Ⅳ can stimulate stem cells to differentiate into nerve cells in vitro. Naomaitong or danshen combined with bone marrow mesenchymal stem celltransplantation can promote neurological recovery from cerebrovascular diseases in rats. Buyang Huanwu Decoction can significantly promote the proliferation of neural stem cells in the subventricular zone and neurological recovery after cerebral ischemia. Chinese herbs, such as Zhichan Decoction and Panax notoginseng, can promote survival of transplanted cells and prevent most cellapoptosis in the stem celltherapy for treatment of Parkinson’s disease. Therapy of benefiting qi and elevating yang or ginsenosides Rg1 combined with stem celltherapy can improve memory ability of dementia rats. Traditional Chinese medicine exerts a catalytic role in the stem celltherapy for cerebrovascular diseases.

Herbal prescription science is a bridge between basic and clinical subjects in traditional Chinese medicine (TCM). In studying the doctrines in the general textbook Herbal Prescription Science and applying them to clinical practice, it was found that they are imprecise and inapplicable. Based on the analysis of Suanzaoren Decoction, Xiaoqinglong Decoction, Jichuan Decoction, etc., the authors point out that this problem is due to the current pathogenesis-based research approach of the herbal prescription science. It is proposed that correspondence between formula and syndrome is the core of the herbal prescription science. In order to solve such a problem, searching for corresponding relationship between an herb or a formula and the signs and symptoms of a syndrome or disease should be the most important task in research of herbal prescription science, for emphasis on attention to the objective indications and evidence in clinical utilization of herbal formulas is the major feature of the herbal prescription science according to medication experience in the long history of TCM.

The scientific and rational application of diagnostic marker is very important significant in the early detection and treatment of cardiovascular diseases.The emergence of cardiac-specific troponin and the development of high assays make it possible for early noninvasive diagnosis of acute myocardial infarction.The Natriuretic peptide used for the diagnosis of heart failure is a new cornerstone in the history of cardiac markers development.The future trends in new methodology development may find more potential new early markers and predictive factors,which could bring in new prospects for the early diagnosis and treatment of cardiovascular diseases,but also more challenges for clinicians and laboratory physicians.

Objective To explore therapeutic effects of acupuncture combined with puerarin injection in the treatment of patients with sudden deafness.Methods 83 patients with sudden deafnss were randomly divided into 2 groups.Control group(n =38) received puersrin injection.Treatment group ( n =45 ) received acupuncture received acupuncture combined with puerarin injection.The effect was compared between the two groups.Results The effective rate of treatment group was 86.7％,and was higher than that of control group(73.6％ ) ( P ＜0.05 ).The hearing function of treatment group was better than that of the control group after treatment ( t =6.21,P ＜ 0.01 ).Conclusion Acupuncture combined with puerarin injection in the treatment of patients with sudden deafness could obtain good curative effect,and it was worth to be spread and studied in the clinic.

OBJECTIVE:To investigate the pharmacokinetic profiles of baicalin(a constituent in Sanhuang decoction) in rats.METHODS:Blood samples were collected as schedule from rats after intragastrically administration of Sanhuang decoction, then the content of baicalin was determined by HPLC and the chief pharmacokinetic parameters were computed.RE SU1TS:The chief pharmacokinetic parameters of baicalin in rats were as follows:t_(max1)=(15?4.23) min;t_(max2)=(6.8?0.54) h;C_(max1) =(4.49?1.56)?g?mL~(-1);C_(max2)=(3.25?1.23)?g?mL~(-1);AUC =(35.52?12.35)?g?h?mL ~(-1);t_(12)=(5.12?0.23)h;CL=(3.86?0.91) 1?h~(-1).CONCLUSION:The method is simple in sample treatment,rapid and accurate,specific and sensitive,and it can be used as a means for the monitoring of the serum concentration of baicalin containing Chinese patent medicines and so as to provide reference for clinical rational drug use.

The paper discusses the difference in postgraduate training between China and the United States,intending to supply some advanced experiences for Chinese postgraduate education reform.