1.Indoor Air Pollution and Its Health Effects in Newly Decorated Rooms
Hengsheng HU ; Xinying ZHANG ; Wenshan HUANG
Journal of Environment and Health 1993;0(01):-
Objective To explore the indoor air pollution and its health effects in newly decorated rooms. Methods Indoor air sampling was conducted in rooms of 13 newly decorated apartments during the period from the 1st day to the 4th day, the 2nd month and the 6th month after the decoration. The levels of formaldehyde, benzene, o-dimthylbenzene, m-dimethylbenzene, para-dimethylbenzene in air samples were analyzed. An epidemiological investigation on the adverse response of eye and respiratory system was carried out among the family members before and after decoration. Results The levels of formaldehyde, benzene and dimethylbenzene in indoor air exceeded ther related standards more than 2.92 times, 7.4-11.3 times, 58.2-87.1 times respectively, and showed a decreasing trend with the prolongation of time after decoration. The positive rates of shedding tears and sneezing, branchitis or cough, asthma, dizziness among family members were 0%, 3.0%, 3.0%, 0% respectirely before decoration and rose to 24.2%, 7.6%, 6.1%, 7.6% respectively after decoration. Conclusion The indoor decoration resulted in the indoor air pollution by formaldehyde and benzene compounds, the contamination degree showed a positive correlation with the degree of complicated decoration and was associated with the quality of decorative materials. Indoor decoration also resulted in the increasing positive rates of adverse response of eye and respiratory system.
3.Effects of Air Quality on the Respiratory System of Pupils
Hengsheng HU ; Li HUANG ; Xinying ZHANG
Journal of Environment and Health 1989;0(06):-
Objective To study the effects of air quality on the the respiratory system of pupils. Methods Based on the routine monitoring data of Nanning City from Nanning environmental monitor station , all pupils from three elementary schools which located in heavy polluted area, middle polluted area and light polluted area respectively were investigated. The atmosphere quality was assessed with Shanghai Atmosphere Environmental Index. The illness data were collected by epidemiological investigation, questionnaire and physical examination. Chi-square test and Logistic regression were employed in the statistic analysis. Results The morbidity of bronchitis, pneumonia, asthma, rhinitis, etc. in pupils lived in heavy polluted area was higher than that in light polluted area (P
4.Design and Implementation of Mobile Nursing Station
Hui ZHANG ; Yali JI ; Chengwei HU ; Xinying LIU
Chinese Medical Equipment Journal 1989;0(02):-
Objective To solve the problem that traditional electronic medical records(EMR) system could not be extended to patients' bedside because of the wired network connection restrictions.Methods Based on wireless transmission and data synchronization technologies in PDA,a mobile nursing station was developed.Results Such functions were realized as patient identity verification,implementation of doctor's orders and vital signs collection beside patients' bed.Conclusion Technical support is provided for closing EMR information chain and improving medical quality.[Chinese Medical Equipment Journal,2008,29(2):53-54]
5.Bone mesenchymal stem cells with allogeneic bone to repair canine mandibular defects:detection of osteogenic ability
Caixia JING ; Changkui LIU ; Xinying TAN ; Jinchao LUO ; Min HU
Chinese Journal of Tissue Engineering Research 2015;(14):2138-2143
BACKGROUND:Al ogeneic bone has anatomical appearance and biological features similar to autogenous bone, which is an excel ent biological scaffold material. Mesenchymal stem cel s originating from autogenous bone marrow have mutli-lineage differentiation potential, can differentiate into osteoblasts and chondrocyte, and thus can accelerate the formation of bone tissue and cartilage tissue. OBJECTIVE:To establish the osteogenic ability of al ogeneic bone with autogenous bone marrow mesenchymal stem cel s for repairing major mandibular defects. METHODS:The left mandibular teeth of 24 beagles were extracted, and at 2 months after wound healing, mandibular defects were made artificial y. The beagles were divided into two groups:control group treated with lyophilized al ogeneic bone, and experimental group with autogenous bone marrow mesenchymal stem cel s and lyophilized al ogeneic bone. Densitometry with CT and Micro-CT was conducted 4, 12, and 24 weeks after surgery. RESULTS AND CONCLUSION:Compared with the control group, the bone density of the mandible was significantly higher in the experimental group at 12 weeks after transplantation (P<0.05). Over time, the bone densities in the two groups were both increased, but the bone density in the experimental group was always higher than that in the control group. Bone structure parameters were progressively increased or decreased in the two groups, especial y in the experimental group. At 24 weeks after surgery, the degree of trabecular separation in regions of interest was higher in the experimental group than the control group (P<0.05), but the bone volume fraction, number of trabecular bone, and bone trabecular thickness were significantly lower in the experimental group than the control group (P<0.05). These findings indicate that bone marrow mesenchymal stem cel s are capable of accelerating the reconstruction of al ogeneic bones.
6.Lyophilizing canine allogeneic mandible:meeting the requirements for rebuilding strength, shape and support capabilities
Caixia JING ; Changkui LIU ; Xinying TAN ; Min HU
Chinese Journal of Tissue Engineering Research 2015;(25):3977-3982
BACKGROUND:The favorable structure and biological characteristics of al ogeneic temporomandibular joint become an effective solution for condylar defect, but immunologic rejection and slow ossification are the main problem for the presence of bone al ograft. OBJECTIVE:To meet the requirements of rebuilding mandible defect by lyophilizing canine mandible. METHODS:The periosteum, soft tissue, and cartilage of 12 canine mandibles were removed. 1 mm diameter hole was dril ed with 1 to 2 cm intervals in their cortical bones with a fissure bur. After washing, they were placed into a-4 ℃ refrigerator for 12 hours, and then stored at-80℃gradual y for 1 week. The mandibles were put in a drier. When the moisture content of osseous tissue decreased to 5%, the bones were packed in aseptic environment, radio pasteurized, and stored in vacuum container at atmosphere temperature. A biomechanical test was conducted after the lyophilization. RESULTS AND CONCLUSION:The maximum shifts of lyophilized mandibles in compression and bending tests were slight according to the steep load-shift curve. The plastic zone was insignificant and fractures appeared immediately when the pressure exceeded the plastic zone. The maximum load, maximum shift, and rigidity in the compression test were (5 163.10±730.16) N, (0.78±0.19) mm and (11 069.17±1 758.12) N/mm, respectively. The data in bending test were (486.67±134.12) N, (0.67±0.15) mm and (1 151.67±256.46) N/mm, respectively. It is concluded that the dehydrated and lyophilized canine mandibles have good shape and support ability and can meet the mechanical requirements in repairing and reconstructing mandibular defect.
7.Pretest of the Primary-Level Personnel Guiding Handbook for Schistosomiasis Control (probationary edition)
Guanghan HU ; Weichen HU ; Xianlin HONG ; Baoping WAN ; Shuying XIE ; Ju ZHANG ; Xinying WANG
Chinese Journal of Schistosomiasis Control 1991;0(05):-
Objective To test the scientificity, practicability, feasibility, intelligibility, and acceptability of the Primary-Level Personnel Guiding Handbook for Schistosomiasis Control(probationary edition). Methods Twenty-seven county and village doctors were selected randomly from two schistosomiasis transmission uncontrolled counties in Jiangxi Province as pretest objects. The pretest was carried out with the focus group discussion. Results The proportions of pretest objects who considered handbook had scientificity, practicability, feasibility, intelligibility and acceptability were 59.26%, 85.19%,55.56%,51.85% and 92.59%, respectively, and the pretest objects had proposals and suggestions for modification. Conclusion According to the suggestion and proposal from the pretest objects, the handbook can be modified and published.
8.Pit pattern under magnifying colonoscopy in diagnosis of early colorectal cancer
Jingjing HU ; Xinying WANG ; Yan GENG ; Yali ZHANG ; Side LIU ; Bo JIANG
Chinese Journal of Digestive Endoscopy 2008;25(8):402-405
Objective To evaluate the diagnostic value of pit pattern analysis in detection of early colorectal carcinoma.Methods From November 2004 to August 2007,a total of 1496 colorectal lesions were observed by mannifying colonoscopy with 0.4%indigo carmine staining.The mucosal crypt patterns (classified according to Kudo classification criteria)of these lesions were compared with pathological diagnosis.Results In 1496 lesions,458(30.6%)were non-neoplastic,657(43.9%)were adenoma,and 381 (25.5%)were adenocarcinoma.In 657 adenoma lesions,415 were tubular adenoma,with low grade dysplasia in 363(87.5%),150 were tubulovillous adenomas with hish grade dysplasia in 61(40.7%)and 49 were villous adenoma with hiish grade dysplasia in 42(85.7%).Among the adenocarcinoma lesions,61 were early colorectal cancers and 36 were laterally spreading tumors(LST).The LST lesions ranged from 10 to 62 mm in diameter.The pit pattern of 3 cases was Type Ⅱ,14 were Type Ⅲ,17 were Type Ⅳ and 2 were Type Ⅴ.Conclusion Pit pattern analysis is important in distinguishing tumorous lesions from non-tumorous ones and in improving the diagnosis rate of early colorectal cancer,which helps in choosing appropriate managements.
9.Predictive value of rectal aberrant crypt foci for colorectal cancer and progressive adenoma and its risk factors
Liyun HUANG ; Jingjing HU ; Yinglong HUANG ; Wei GONG ; Xinying WANG ; Bo JIANG
Chinese Journal of Digestive Endoscopy 2010;27(10):513-517
Objective To investigate the predictive value of rectal aberrant crypt foci(ACF)for colorectal cancer(CRC)and progressive adenomas, and to analyze its risk factors.Methods IndependentSample T test, One-Way ANOVA and Chi-square test were used to analyze the mean number and incidence of rectal ACF.Logistic regression analysis was used to assess the predictive value of rectal ACF for progressive adenomas and CRC, and to identify the independent risk factors of ACF.Results Large number of ACF, i.e.more than 5, was a significant risk factor for CRC and progressive adenomas.Age and smoking were both risk factors of ACF, while aspirin was a protective factor.Conclusion ACF of more than 5 is predictive of CRC and progressive adenomas.For prevention of CRC, great importance must be attached to risk factors of ACF.
10.Analysis of clinical characteristics and related factors of feeding intolerance in preterm infants
Xinying DONG ; Lei DONG ; Yunqing HU
Chinese Journal of Primary Medicine and Pharmacy 2018;25(14):1841-1844
Objective To analyze the clinical characteristics and risk factors of feeding intolerance in preterm infants.Methods From March 2015 to February 2017,a total of 156 preterm infants in the Central Hospital of Rizhao were selected.Of them,96 feeding intolerance premature infants were selected as the observation group,and 60 feeding tolerance premature infants were selected as the control group.The clinical characteristics of the two groups were analyzed,and the risk factors of feeding intolerance in preterm infants were analyzed by logistics multivariate analysis.Results In the infants with gestational age <30 weeks,abdominal distension(34.6%)and gastric reten-tion(50.0%)had the highest incidence rate.In the infants with gestational age 33 -37 weeks and weighing more than 2 500g,the incidence rate of vomiting (45.0%)was highest.In the infants with open milk time no less than 72h,the incidence rate of vomiting(39.3%),abdominal distension(35.7%),gastric retention(44.6%)were signifi-cantly higher than those of the infants with open milk time less than 72h.In the infants with gestational age <30 weeks,the proportion of hypoglycemia(23.1%),significantly reduced body mass(19.2%)were significantly higher than those of the other gestational age,the differences were statistically significant(χ2=5.682,4.235,3.452,4.763, 5.526,3.984,6.224,5.341,all P<0.05).Compared with the control group,in the observation group,the gestational age[(30.4 ±1.3)weeks vs.(33.6 ±2.6)weeks]was smaller,birth weight[(1693 ±467)g vs.(1868 ±537)g]was lower,open milk time[(46.8 ±18.8)h vs.(32.7 ±17.7)h]and defecation time[(58.6 ±12.8)h vs.(39.6 ± 10.6)h]were later,the proportion of the use of respirator(32 cases vs.9 cases),premature rupture of membranes (26 cases vs.6 cases),early pregnancy(51cases vs.15 cases)and perinatal diseases(49 cases vs.12 cases)were higher,the differences were statistically significant(t =5.675,4.967,9.367,7.678,χ2=6.523,5.564,6.652, 7.157,all P<0.05).Logistics multivariate analysis showed that gestational age <33 weeks,birth weight<1500 g, open milk time>3d,ventilator and preterm infants were independent risk factors for feeding intolerance in preterm infants.Conclusion The common clinical manifestations of feeding intolerance in premature infants include vomi-ting,abdominal distension and gastric retention.Gestational age less than 33 weeks,birth weight<1500 g,open milk time>3d,ventilator and preterm infants are independent risk factors for feeding intolerance in preterm infants.