Enterovirus 71(EV71) infection complicated with neurogenic pulmonary edema (NPE) is an important complication and the main death cause of hand-foot-mouth disease in children. The exact pathogenesis has not yet fully understood. Peripheral sympathetic nervous system hyperexcitability has been recognized, but its central positioning and machanisms are debatable. In recent years, people emphasized the release of cytokines caused by the brainstem injury and/or systemic inflammatory response also plays a very important role in the formation of NPE.The interventions at present are mainly symptomatic treatment in the nervous system involvement, respiratory and circulatory failure. Vaccines are still in the experimental phase of exploration. There is a certain distance from clinical application.

Electrically Powered Wheelchairs Standards (GB/T 12996-1991) is being modified in China. With the help of the test methods from the international standard, European standard and Japanese standard, in contrast to Chinese national standards, the article discussed the new Electrically Powered Wheelchairs Standards.

〔Abstract〕 By literature investigation , the paper describes the current research status of the relevance between the international co -author mode and paper citation , including characteristics of current researches on the analysis level , subject and method , etc.In combi-nation with the current research status and requirements of scientific research evaluation , it provides suggestions for the conduction of re-search activities in this field .

A model for measuring the impact of Chinese papers published by hospitals in China was established, followed by an analysis of the contribution of the total citations, the number of fund-supported papers, the number of papers published in core journals, the number of papers published in core journals of Chinese Medical Associa-tion to the impact of papers, which showed that these parameters could effectively measure the impact of Chinese papers published by class A hospitals in China.

As one of pharmaconutrients,it has been proved that ?-3 polyunsaturated fatty acids can regulate inflammation and immunological function because not only its metabolites are different from other lipids but also it can affect intracellular signal transduction.So the structure、composition and molecular mechanisms of ?-3 polyunsaturated fatty acids are reviewed in this article.

As one of lipid nutrients,it has been proved that ?-3 polyunsaturaed fatty acids can effectively be used in the patients with sepsis,cancer,transplantation,chronic inflammatory diseases and so on,which is related with the molecular mechanisms of regulating the structure and function,cytokines and so on.So the clinical study of ?-3 polyunsaturaed fatty acids on different diseases is reviewed in this article.

Laterally spreading tumor is a new type of colorectal tumor found recently.For its particular shape and develptment of tumor,LST is divided as an independent tumor.LST is associated with colorectal cancer and more research is done on it .The progress of its epidemiology, oncomolecularbiology, diagnosis and therapy is reviewed.

Selenium, iodine and zinc are the essential trace elements for human body and the important components of many kinds of hormones, proteins and enzymes. The three elements can play important biological roles by affecting the hormones, proteins and enzymes in human body, one of the three elements can influence the biological effects of the other two. For preventing and curing some deficiency diseases and supernutrition, to study the correlated biological effect of the three trace elements will demonstrate the important theory significance and practical value.