Objective To design the mushroom covered stent and study the primary application for gastroesophageal anastomosis thoracic cavity fistula.Methods On the base of the peculiar anatomic structure and the pathological changes of gastroesophageal anastomosis thoracic cavity fistula, we designed the mushroom covered stent. Under the fluoroscopic guidance, 6 mushroom covered stents were placed in 5 patients.Results The fistula oral of the patients with post operative perforation were closed with the mushroom covered stent, the food intake ability and nutriture of all patients were improved.Conclusions The structure of the mushroom covered stents is reasonable, which is effective and safe for treating the patient with gastroesophageal anastomosis thoracic cavity fistula.