1.Both Heart and Brain as Organs of Spirit:Concept of Heart-brain Integration
Chinese Journal of Rehabilitation Theory and Practice 2016;22(3):368-370
The interaction between heart and brain has drawn more and more attention in recent years. The concept of heart-brain inte-gration has been gradually established, which means the interaction in physiology and pathology between the two organs. On the basis of nerve-fluid system, sympathetic nervous system and renin-angiotensin-aldosterone system (RAAs) are involved in the modulation of heart and brain. As review of the ancient literature of China, heart and brain were considered as the organs of cognition and behavior, which are the functions of only brain from modern science. Several recent researches supported the opinions of ancient Chinese scholars in some ways.
2.Test and analysis on illuminance in reading room
Youjun ZHANG ; Xinting ZHANG ; Hongxun SUN
Chinese Journal of Radiology 2001;0(09):-
0.05),that is to say, IRR couldn′t be improved just because the grade of the hospital was higher. (3)Comparing the photographic department with the non photographic one, we could see there was noticeable difference(? 2=4.081 3, P
3.Advance in Spasticity after Stroke(review)
Weijun GONG ; Tong ZHANG ; Xinting SUN
Chinese Journal of Rehabilitation Theory and Practice 2008;14(3):212-213
Stroke is common clinically and spasticity is one of the main symptoms.There is some advance in recognition of the spasticity after stroke in the basic and clinic,but it remains obscure.
4.Effects of Needle Retaining on Haemodynamics of Anterior Tibial Artery During Acupuncture
Tong ZHANG ; Weijun GONG ; Xinting SUN
Chinese Journal of Rehabilitation Theory and Practice 2009;15(11):1044-1045
Objective To study the relationship between needle retaining anddeqi. Methods Manual acupuncture was performed at the left ST36 of 26 naive healthy adult volunteers. Half of them retained the needles for 6 min and others were put the needle out immediately afterdeqi. Hemodynamic parameters of the anterior tibial artery were observed with color Doppler ultrasonography before and at 0, 1, 2, 3, 4, 5 min after acupuncture. Results There was significant difference in Vmax、Vm、Pi and Dist in anterior tibial artery before and 3 min after acupuncture, but wasn't between needle remaining and not. Conclusion Needle retaining cannot change the regional haemodynamics during acupuncture, which suggest it cannot strengthendeqi.
5.Evaluation of long term cognitive disorder after traumatic brain injury models by controlled cortical impact
Mengqi HAN ; Hao ZHANG ; Xiaonian ZHANG ; Xinting SUN
Chinese Journal of Physical Medicine and Rehabilitation 2015;37(1):1-6
Objective To evaluate the method of controlled cortical impact(CCI) on long term cognitive disorder after traumatic brain injury(TBI) and to investigate the possible pathological mechanism.Methods Sixty male SD rats were randomly assigned into 3 groups:sham surgery group(n =10),control group (n =10) and CCI group(n =40).CCI application was used to make the bilateral frontal lobe controlled cortical impact model (depth:1.5 mm,velocity =3.5 m/s,dwell time =400 ms).Morris water maze test and Nissl's staining was used to assess the cognitive function and pathological changes after 8 weeks of CCI.The expressions of brain derived neurotrophic factor (BDNF) and tyrosine protein kinase B (TrkB) mRNA in frontal lobe and hippocampus tissue was detected by reverse transcription polymerase chain reaction(RT-PCR).Results The mortality in CCI group was only 12.5%.Morris water maze test results showed the escape latency in CCI group was longer than that in sham surgery and control groups(F =51.784,P < 0.05).Percent of time spend in goal quarter during probe trial in CCI group was significantly less than that in sham surgery and control groups(F =13.468,P < 0.05).Nissl's staining showed frontal lobe had obviously defects; Nissl's bodies of frontal cortex and CA1 region in hippocampus reduced.The expressions of BDNF and TrkB mRNA in frontal lobe and hippocampus were significantly less than those in sham surgery and control groups(P < 0.05).Conclusions The CCI model can be applied for study on long term cognitive disorder after TBI with good stability and repeatability.Using the experimental parameters of CCI can damage the long term cognitive function after TBI in rats,and lead the pathology changes of brain tissue clearly.This may have some relationship with the expressions of BDNF and TrkB mRNA.
6.Diffusion tensor imaging and the Montreal cognitive assessment for assessing severe traumatic brain injury
Xiaonian ZHANG ; Yajing HOU ; Xinting SUN ; Qianqian CHI ; Hao ZHANG
Chinese Journal of Physical Medicine and Rehabilitation 2014;36(4):266-269
Objective To investigate any correlation between diffusion tensor imaging (DTI) results and Montreal cognitive assessment (MoCA) scores after severe traumatic brain injury (TBI).Methods Eight male pa-tients with chronic severe TBI were given the MoCA (including memory,attention,speech and executive function).DTI was used to quantify the fractional anisotropy (FA) of white matter fiber tracts in the radial and longitudinal fasciculus,under longitudinal fasciculus,internal capsule,corpus callosum genu and body,and the cingulate cortex.Pearson correlation coefficients were calculated to quantify the correlation between the FA values and MoCA scores.Results There was a positive correlation between FA in the corpus callosum body,corpus callosum genu and the superior longitudinal fasciculus and MoCA total scores.Conclusion The MoCA scores of patients with chronic severe TBI are related to white matter damage in the corpus callosum body,corpus callosum genu and the superior longitudinal fasciculus.
7.Change of Pituitary Hormones after Traumatic Brain Injury(review)
Qianqian CHI ; Hao ZHANG ; Xiaonian ZHANG ; Xiaoyan WANG ; Xinting SUN
Chinese Journal of Rehabilitation Theory and Practice 2010;16(10):944-946
The change of pitutary hormones can occur in any time after traumatic brain injury, the main cause is primary or secondary impairment of hypothalamus as well as pituitary after brain injury. It is important to further research when to test hormone and to carry on the hormone replacement therapy.
8.Cost-Effectiveness Analysis of Rehabilitation of Traumatic Brain Injury at Different Stages
Hao ZHANG ; Xiaonian ZHANG ; Xiaoyan WANG ; Xinting SUN ; Qianqian CHI
Chinese Journal of Rehabilitation Theory and Practice 2010;16(10):966-968
ObjectiveTo study the effect of a course of regular rehabilitation treatment on patients with different traumatic brain injury(TBI) course, explore the costs of one rehabilitation course in patients with different TBI course, and study the timing and focus of rehabilitation on patiens with different stages.Methods250 TBI patients were distributed to five groups by different TBI courses: <3 months, 3~6 months, 6 months~1 year, 1~2 years and >2 years. The clinical data and initial function evaluation were done at the admission. All of them received at least one regular rehabilitation treatment, then another function evaluation was done. Effects and costs of one rehabilitation course in patients with different TBI course were investigated.ResultsThe longer the duration of illness, the higher the cost-effectiveness ratio. The cost-effectiveness ratio of the second treatment course was higher than the first one. The patients within 12 months should receive a comprehensive rehabilitation treatment, and should be prevented and treated hydrocephalus and other complications; for patients within 1~2 years, there would be no significant improvement in balance and lower limb function, should enhance the training of activity of daily living (ADL) and upper extremity function; for the patients more than two years just improved ADL using of residual function.ConclusionTBI patients should accept rehabilitation as soon as possible, and should be conducted corresponding trainings according to different disease course.
9.Effects of Electroacupuncture at Zusanli (ST36) on Lower Limbs Motor Function in Patients with Stroke during Spasm Period:A Clinical Research
Weijun GONG ; Tong ZHANG ; Lihua CUI ; Yuqi YANG ; Xinting SUN
Chinese Journal of Rehabilitation Theory and Practice 2008;14(11):1057-1058
Objective To observe the effects of electroacupuncture at Zusanli (ST36) on lower limbs motor function in patients with stroke. Methods 63 patients were evenly randomized into electroacupuncture group and control group. All the patients received routine rehabilitation training and at the same time,patients in electroacupuncture group, received electroacupuncture at zusanli (ST36). They were assessed with Fugl-Meyer Assessment (lower limb, hip, knee and ankle), gait analysis (gait frequency, gait speed and step length of both sides) and lower limb Composite Spasm Scale (CSS) before and after treatment. Results The scores of Fugl-Meyer Measure, gait analysis, and CSS improved in both groups, and more significantly in electroacupuncture group. Conclusion Electroacupuncture at zusanli (ST36) can significantly improved lower limb motor function without worsening the spasm.
10.Changes of Thyroid Hormone and Reproductive Hormone in Post-acute Severe Traumatic Brain Injury
Xiaoyan WANG ; Qianqian CHI ; Xinting SUN ; Hao ZHANG
Chinese Journal of Rehabilitation Theory and Practice 2011;17(4):365-367
ObjectiveTo observe the changes of thyroid hormone and reproductive hormone in post-acute traumatic brain injury(TBI).Methods70 post-acute TBI patients were selected from Beijing Charity Hospital from September 2009 to March 2010. The levels of thyroid stimulating hormone(TSH), triiodothyronine(T3), thyroxine(T4), free triiodothyronine(FT3), free thyroxine (FT4), follicie stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), progesterone (P), and testosterone (T) were measured at 7 a.m. to 8 a.m. on the second day of admisson. According to the reference ranges, the total abnormal rate and the single hormone abnormal rate were calculated. According to the level of hormone, the subjects were divided into the normal group and the abnormal group. The two groups were compared in gender, age, course of disease, duration of coma, basal fracture and scores of Disability Rating Scale (DRS).ResultsThe total abnormal incidence of anterior pituitary hormone was 77.1% in post-acute TBI. The abnormality of reproductive hormones was higher. The duration of coma was related to the reproductive hormone.ConclusionThe abnormal incidence of anterior pituitary hormone occurs frequently in post-acute TBI. The duration of coma is related to the reproductive hormone.