1.The progress of research about anatomy of posterolateral wall of maxillary sinus in endoscopic surgery.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(24):2181-2184
As an important landmark, the posterolateral wall of maxillary sinus can help to locate numbers of significant signs such as maxillary artery and its branches, maxillary nerve and infraorbital nerve, infratemporal fossa and pterygopalatine fossa etc. in the endoscopic surgery for paranasal sinuses and lateral skull base. This article reviewed related researches about the anatomy and endoscopic surgery of posterolateral wall of maxillary sinus.
Endoscopy
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Humans
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Maxillary Artery
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Maxillary Nerve
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Maxillary Sinus
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anatomy & histology
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Nasal Surgical Procedures
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Pterygopalatine Fossa
2.Primary abdominal aortic aneurysm-intestinal fistula(a case report and literature review)
Xinsheng LU ; Yixong LI ; Jingdong LI ;
Chinese Journal of General Surgery 1994;0(05):-
Objective To study the diagnosis and treatment of abdominal aortic anurysm-intestinal fistula(AAA-IF). Methods The diagnosis and treatment of one patient with AAA-IF was reported, while a literateres review of AAA-IF was made. Results A 50 years old femal patient abmitted due to upper abdominal pain for two month, and an AAA was found in the explore laparotomy. The patient suddenly occurred severe upper abdominal pain accompanied with shock and massive upper gastrointestinal bleeding 13 days after the operation. The preoperative suspected diagnosis was AAA-IF. An AAA-IF was ound during emergent operation. AAA-IF resection with artifial vessel replacement, resection of the forth portion of duodenal and upper portion of jejunal were performed together. The patient recovered eventurely except high body temperature. After vigovous antibiotics therapy, the patient recovered. Conclusions AAA-IF is a rare disordor, the mortality can be as high as over 30%. The key points of redecing mortality are that the diagnosis and treatment should be in time; postoperative vigorous antibiotics should be given, because the AAA-IF patient tends to occur septic complications due to the communication occurred between the AAA and intestinal tract.
3.Experimental study of human umbilical cord blood cells transplantation for treatment of cerebral ischemia in rats
Fenghua PAN ; Xiaobo LI ; Xinsheng DING
Journal of Clinical Neurology 1988;0(02):-
Objective To explore the effect of human umbilical cord blood cells (HUCBCs) transplantation to treat cerebral ischemia of rats and the status of transplanted HUCBCs in the ischemic brain tissue of these rats. Methods The mononuclearcells abstracted from 60~100 ml of cord blood of full-term babies were cultured in vitro and marked with 5-bromodeoxyuridine (Brdu)(5 ?mol/L) for 2 days. The middle cerebral artery occlusion rat models were made and the HUCBCs (3?106) were transplanted into the lateral ventricular 1 day later. Neurological severity scores (NSS) tests were undertaken at different time point after transplantation, and iimmunohistochemistry method was used to check the migration and differentiation of HUCBCs. Results The HUCBCs had the capacity of proliferation in vitro and were induced to differentiate into astrocytes, oligodendrocytes and neurons in vivo. 3 weeks later, the neurological function of rats that received transplantation recovered much better than the rats without transplantation, as evidenced by NSS (all P
4.Evaluation of the primary outcomes of minimally invasive lumbar microdiscectomy
Xinsheng PENG ; Liyan CHEN ; Fobao LI
Chinese Journal of Microsurgery 2008;31(2):101-103
Objective To evaluate the primary outcomes of minimally invasive lumbar microdiscectomy. Methods There were 34 cases with single lumbar disc herniation treatment of tubular retractor access with METRx system and microdiscectomy(MMD group)and same cases with treatment of conventional discectomy(CD group).Operating time,blood loss,time of leaving the bed and length of hospital stay were compared in two groups.The postoperative wound pain was measured using a visual analog scale(VAS).The modified MacNab criteria were used to evaluate the outcomes. ResuIts The mean operating time was 65 min in MMD group,63 min in CD group.The mean blood loss was 34 ml in MMD group,85 ml in CD group.To compare in two groups,there was significant difference(P<0.05).The mean time of leaving the bed after operation was 3.2 d in MMD group.5.8 d in CD group.The mean length of hospital stay was 5.8 d in MMD group.9.6 d in CD group.The mean VAS of the postoperative wound pain was 3.2 scores in MMD group,5.6 scores in CD group.To compare in two groups,there was significant difference(P<0.05).There was one complication in MMD group,4 in CD group.Thirty-three cases got follow-up mean 8.5 months in MMD group.The success rate was 93.9%. Conclusion The minimally invasive lumbar microdiscectomy has the advantages on less trauma,safety,quickly postoperative recovery,and satisfactory outcomes.
5.Protective Effects of Endothelin Receptor Antagonist on Traumatized Spinal Cord in Rats
Xinsheng PENG ; Fobao LI ; Tao PAN
Orthopedic Journal of China 2001;8(2):145-147
Objective: To evaluate the effects of PD145065(non-selective endothelin(ET)receptor antagonist)on injured spinal cord and explore mechanisms of how ET plays a role in secondary injury following spinal cord injury(SCI).Methods:Spinal cord of rat was traumatized by compression(50g,1min).PD145065 or vehicle was administered intrathecally 10 minutes before SCI.Alterations of spinal cord blood flow(SCBF),molondialdehyde(MDA),the total content of intracellular calcium([Ca2+]i),Evans blue(EB),and water in spinal cord were inspected.Results:SCBF of injured area decreased obviously 5 minutes after SCI.SCBF was 75.23±9.21% of baseline 5 minutes after SCI,57.06±7.35% 2 hours.SCBF of adjacent area decreased lower.SCBF was 79.82±7.98% of baseline 30 minutes after SCI.SCBF of injured and adjacent areas did not recover 4 hours after SCI.The contents of MDA,[Ca2+]i,EB and water in traumatized spinal cord were significantly more than that of sham(P<0.05)。PD145065 ameliorated SCBF of injured area obviously and abolished the decrease of SCBF of adjacent area.The contents of MDA,[Ca2+]i,EB and water in spinal cord of PD145065 treated group were significantly less than that of saline treated group(P<0.05).Conclusion:PD145065 has protective effects on traumatized spinal cord in early phase.ET and its receptors may play a role in secondary injury following SCI by multiple pathways.ETA/ETB receptor antagonist may be useful in treatment of clinical SCI.
6.Pigment epithelium-derived factor and tumor
Xinsheng WANG ; Hua LI ; Xiaomin WANG
Journal of International Oncology 2011;38(4):248-250
Pigment epithelium-derived factor (PEDF), a member of the serine protease inhibitor (serpin) family, is well known for its endogenous antiangiogenic activity. The down-regulation or depletion of PEDF has been shown in many tumor tissues, and it was proved to be correlated with the prognosis of tumor. At present,the biological properties of PEDF and the mechanism of its anti-tumor activity have become a focus research, and it provides theoretical foundation to the treatment of carcinoma.
7.Clinical application of ischemic preconditioning on patients with primary hepatic carcinoma underging hepatectomy
Xinsheng LU ; Guohuang HU ; Xiaogang LI
Chinese Journal of General Surgery 2001;0(09):-
0.05).(2)Serum ALT,AST and LDH:After reperfusion,the values of ALT,AST,and LDH in IP group were significantly lower than those in I-R group(P
8.Materal-neonatal safety and stress during spinal and epidural anesthesia for cesarean section
Xinsheng ZHAO ; Shuren LI ; Jinfeng QU
Chinese Journal of Anesthesiology 1995;0(02):-
The materal-neonatal safety and materal stress response were evaluated during intratheeal anesthesia. Method: Forty-two parturients(ASA grade 1 )were randomly divided into two groups: spinal group (n=21), epidural group (n=21). 3 ml of 0.5% hyperbaric bupivacaine was given in spinal group; 12-15ml of 0.75 % bupivacaine was administrated in epidural group. Materal arterial samples were drawn before anesthesia,after anesthesia induction, after delivery and at the end of surgery; umbilieal venous samples were taken for measurements of blood catecholamine, sugar and lactate concentrations. Result; Compared with those before intrathecal blockade, plasma levels of catecholamine of two groups were significantly decreased in different periods during anesthesia (P0.05); there were not any significant differences between the two groups in neonate Apgar scores. Conclusion:Both of two techniques can inhibit stress response of parturients to cesarean sections and have no adverse effects to neonates when applied in proper management.
9.Analysis on Therapeutic Effects of 209 Cases of Allergic Asthma Treated with Acupoint Application
Xinsheng LAI ; Yuemei LI ; Zhaojin FAN
Journal of Traditional Chinese Medicine 1992;0(11):-
209 cases of allergic asthma were randomly divided into two groups, which received respectively traditional medicinal vesiculation and drug application based on syndrome differentiation, and their short - term and long - term therapeutic effects were investigated and compared, and the relation between the clinical therapeutic effects of the two application therapies and classification of TCM syndrome differentiation was further analysed. Results show that the total effective rate of the short -term of drug application based on syndrome differentiation is higher than that of medicinal vesiculation, and the clinical thertapeutic effect is closely related to classification of syndrome differentiation, the therapeutic effect of the short -term is the highest for lung -heat type and the worst for Yang-deficiency of kidney.
10.Ultrastructure Alteration of the Gallbladder in Rabbits With Gallstone Before and After Cholecystolithotomy
Zuori LI ; Zijiang WANG ; Xinsheng LU
Journal of Chinese Physician 2001;0(08):-
Objective To explore the relationship between the ultrastructure and gallstone recurrence after cholecystolithotomy.Methods By implanting human cholesterol gallstone into the gallbladder of rabbits, the ultrasructure of the gallbladder was observed with scanning eleetron microscope and transmission electron microscope,3 months before and after cholecystolithotomy.Results ln the stone-implanted group,the epithelium cells were massively damaged,nuclei karyopyknosis,mitochondria destroyed, and phagolysosomes increased. After the gallstone removal, the epitheliune cells did not recover completely where exposed connective tissues and covering surface by mucus. In cytoplasm, the lysosome decreased, and mucus granules secretion increased and actively secreted into the gallbladder lumen.Conclusions The pathologic changes of chronic cholecystitis caused by implanting stones in rabbits is similar to that of the chronic calculous cholecystitis in human.The basic cause of gallstone recurrence after cholecystolithotomy might be that the ultrastructural changes not be restored and the mucus secretion increased obviously in gallbladder.