1.The progress of research about anatomy of posterolateral wall of maxillary sinus in endoscopic surgery.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(24):2181-2184
As an important landmark, the posterolateral wall of maxillary sinus can help to locate numbers of significant signs such as maxillary artery and its branches, maxillary nerve and infraorbital nerve, infratemporal fossa and pterygopalatine fossa etc. in the endoscopic surgery for paranasal sinuses and lateral skull base. This article reviewed related researches about the anatomy and endoscopic surgery of posterolateral wall of maxillary sinus.
Endoscopy
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Humans
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Maxillary Artery
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Maxillary Nerve
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Maxillary Sinus
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anatomy & histology
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Nasal Surgical Procedures
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Pterygopalatine Fossa
2.Primary abdominal aortic aneurysm-intestinal fistula(a case report and literature review)
Xinsheng LU ; Yixong LI ; Jingdong LI ;
Chinese Journal of General Surgery 1994;0(05):-
Objective To study the diagnosis and treatment of abdominal aortic anurysm-intestinal fistula(AAA-IF). Methods The diagnosis and treatment of one patient with AAA-IF was reported, while a literateres review of AAA-IF was made. Results A 50 years old femal patient abmitted due to upper abdominal pain for two month, and an AAA was found in the explore laparotomy. The patient suddenly occurred severe upper abdominal pain accompanied with shock and massive upper gastrointestinal bleeding 13 days after the operation. The preoperative suspected diagnosis was AAA-IF. An AAA-IF was ound during emergent operation. AAA-IF resection with artifial vessel replacement, resection of the forth portion of duodenal and upper portion of jejunal were performed together. The patient recovered eventurely except high body temperature. After vigovous antibiotics therapy, the patient recovered. Conclusions AAA-IF is a rare disordor, the mortality can be as high as over 30%. The key points of redecing mortality are that the diagnosis and treatment should be in time; postoperative vigorous antibiotics should be given, because the AAA-IF patient tends to occur septic complications due to the communication occurred between the AAA and intestinal tract.
3.Pigment epithelium-derived factor and tumor
Xinsheng WANG ; Hua LI ; Xiaomin WANG
Journal of International Oncology 2011;38(4):248-250
Pigment epithelium-derived factor (PEDF), a member of the serine protease inhibitor (serpin) family, is well known for its endogenous antiangiogenic activity. The down-regulation or depletion of PEDF has been shown in many tumor tissues, and it was proved to be correlated with the prognosis of tumor. At present,the biological properties of PEDF and the mechanism of its anti-tumor activity have become a focus research, and it provides theoretical foundation to the treatment of carcinoma.
4.Low molecular weight heparin in the treatment of severe acute pancreatitis
Jieqiu LI ; Kaicheng ZHANG ; Xinsheng LU ;
Chinese Journal of General Surgery 1997;0(04):-
Objective To investigate the effects of low molecular weight heparin (LMWH) on severe acute pancreatitis(SAP). Methods Retrospective analysis was made on the clinical features and therapeutic effect on the routine treatment (RT) group in 48 cases and LMWH treatment(LT) group in 31 cases. Results 28 (90.3%) out of 31 cases were cured while 3 (9.7%) died in LT group. 35(72.9%) out of 48 cases were cured whereas 15 (27.1%) died in RT group. The complications occurring in LT group (32.3%,10 patients 18 times ) was significantly lower than that in the RT group (62.5%,30 patients 59 times)(P
5.Immunohistochemical Study about Expression of Caspase-3 in Hemangiomas
Nan LI ; Xinsheng CHEN ; Daliang CHEN ;
Chinese Journal of Bases and Clinics in General Surgery 2003;0(04):-
Objective To study the relationship between expression of Caspase 3 and regression of hemangioma. Methods Caspase 3 expression was detected in 79 hemangiomas and 5 normal skin tissues by immunohistochemistry (SP). Results In 79 hemangiomas, the positive rates of Caspase 3 expression in proliferating, involuting and involuted phases were 52.4%, 91.2% and 83.3%, respectively. The expression of Caspase 3 in involuted and involuting phases was higher than proliferating phase( P 0.05). Conclusion Caspase 3 is involved in the converting of hemangiomas from proliferating phase into involuting phase. The activation of Caspase 3 may induce apoptosis of endothelial cells, thus leading to the regression of hemagioma.
7.Effects of Acupoint Application on Incubation Period of Asthma andLung Pathological Changes in Guinea Pigs with Asthma
Yuemei LI ; Xinsheng LAI ; Nin SU
Journal of Guangzhou University of Traditional Chinese Medicine 1999;0(02):-
Objective To investigate the microcosmic pathologic mechanism of ac upoint application for asthma. Methods Sixty guinea pigs were randomly alloca ted to three groups: Group A (model control), Group B (guinea pig model treated with acupoint application) and Group C (normal control). Group B was treated wit h the application of herbal medicines on the acupoints located at neck and back. Results From the 6th day of treatment, incubation period of nodding breath was prolonged in Group B as compared with Group A (P
8.Effect of Electroacupuncture on Learning and Memory and Heme Oxygenase in Rats with Vascular Dementia
Xinsheng LAI ; Min LI ; Guofeng XU
Journal of Guangzhou University of Traditional Chinese Medicine 2004;0(06):-
[Objective] To observe the effect of electroacupuncture (EA) on the disorder of learning and memory in rats with vascular dementia (VD) and to explore its molecular mechanism. [Methods] Among 60 male SD rats, 10 rats were in sham-operation group and the other 50 rats were used to establish models of global ischemia and reperfusion by four-vessel occlusion (4-VO) method. Then the survival model rats were randomized into EA group (n = 14) , model group (n = 13) and nimotop group (n = 13). EA group was treated with EA at points of Baihui (GV20) and Dazhui (GV14) , nimotop group with nimotop 12 mg/kg, and sham-operation group and model group did not receive any treatment. After a 20-day treatment, the changes of learning and memory behavior in rats were detected by Morris water maze, as well as the protein expression and mRNA expression of heme oxygenase (HO) . [Results] The escape latent period, HO-1 protein expression and HO-1 mRNA-expression were increased obviously in model rats ( P 0.05). [Conclusion] EA can improve the learning and memory behavior in rats with VD and this may be related to the decrease of HO-1 protein expression and HO-1 mRNA-expression in cortex and hippocampal neurons.
9.Influence of Electroacupuncture on Sperm Count and Quality in Oligoasthenozoospermic Rats
Jing LI ; Xinsheng LAI ; Chengwen TU
Journal of Guangzhou University of Traditional Chinese Medicine 2000;0(04):-
【Objective】To observe the effect of electroacupuncture(EA) on sperm count and quality in oligoasthenozoospermic rats.【Methods】Twenty-four male SD rats were given adenine by intragastral administration to establish oligoasthenozoospermic models.After the modeling,the survival rats were randomized into EA group(N=8) and model group(N=8).EA group was treated with EA of Guanyuan(CV4),Shenshu(BL23) and Sanyinjiao(SP6) acupoints.Other 10 rats served as the normal controls.Sperm samples were analyzed by computer-aided semen analysis system(CASA) and the observed sperm parameters included sperm concentration,semen viability and percentage of forward progressive sperm.【Results】Compared with the normal group,sperm concentration,semen viability and percentage of forward progressive sperm were much decreased in the model group(P
10.Experimental study of human neural stem cells transplantation for treatment of cerebral ischemia in rats
Fenghua PAN ; Xiaobo LI ; Xinsheng DING
Journal of Clinical Neurology 1988;0(02):-
Objective To explore the effect of human neural stem cells(hNSCs) transplantation to treat cerebral ischemic rats and the status of transplanted hNSCs in the ischemic brain tissue of these rats.Methods Human neural stem cells were separated from 10~13 weeks brains of human embryo and were cultured and induced to differentiate. The middle cerebral artery occlusion rat models were made and the human neural stem cells were transplanted through tail vein 1 day later. Neurological Severity Scores (NSS) tests were undertaken in two groups after transplantation. Immunohistochemistry was used to check the differentiation and migration of human neural stem cells in vitro and vivo.Results Neural stem cells from human embryonic brains had been successfully cultured. These cells formed typical neurospheres in suspension, and the majorities expressed nestin. Three weeks later, the neurological function of rats that received transplantation recovered much better than the rats without transplantation, as evidenced by NSS ( P