1.Relationship between dietary inflammatory index during the second trimester of pregnancy and preterm ;birth
Xiaoling YU ; Mei ZHAO ; Hongju WANG ; Chang SU ; Li YUAN ; Manman YUAN ; Xinqiong ZHANG ; Yan HU ; Huan YU ; Jianhong LIAO ; Yuanhua CHEN ; Dexiang XU
Chinese Journal of Clinical Nutrition 2016;24(2):91-95
Objective To assess the diet quality of pregnant women during the second trimester using the dietary inflammatory index ( DII) and to explore the correlation between the DII in second trimester of preg-nancy and preterm delivery.Methods A total of 253 women with singleton pregnancy in 16-20 gestational weeks who had received routine prenatal care between August 2014 and April 2015 at the First Affiliated Hospi-tal of Anhui Medical University were enrolled with cluster random sampling.The included women were asked to recall daily dietary intake in the 3 days prior to the survey.All dietary data were analyzed for energy and nutri-ents intake with a nutritional analysis software, followed by calculation of DII according to previous reports. Based on quartiles of the DII scores, the participants were divided into three groups, namely the anti-inflam-matory group (DII<-5.10), intermediate group (DII -5.10--2.55), and the pro-inflammatory group (DII>-2.55).The participants were followed up until delivery and the pregnancy outcomes were recorded. The relationship between the DII in second trimester of pregnancy and preterm delivery were analyzed. Results DII scores of the 253 pregnant women during the second trimester of pregnancy ranged from -7.913 to 3.872.The risks of preterm birth in the anti-inflammatory diet group, the intermediate group, and the pro-inflammatory diet group were 0, 1.6%, and 6.3%, respectively, with statistically significant differences among the groups (P=0.034).The higher DII scores (pro-inflammatory) were associated with higher inci-dence of preterm birth ( P<0.05 ) .Conclusion DII may be used to assess diet quality of pregnant women during the second trimester and to predict the risk of preterm birth.
2.Prognostic value and predictive threshold of tumor volume for patients with locally advanced nasopharyngeal carcinoma receiving intensity-modulated radiotherapy
He YUXIANG ; Wang YING ; Cao PENGFEI ; Shen LIN ; Zhao YAJIE ; Zhang ZIJIAN ; Chen DENGMING ; Yang TUBAO ; Huang XINQIONG ; Qin ZHOU ; Dai YOUYI ; Shen LIANGFANG
Chinese Journal of Cancer 2016;35(12):725-734
Background:Gross target volume of primary tumor (GTV?P) is very important for the prognosis prediction of patients with nasopharyngeal carcinoma (NPC), but it is unknown whether the same is true for locally advanced NPC patients treated with intensity?modulated radiotherapy (IMRT). This study aimed to clarify the prognostic value of tumor volume for patient with locally advanced NPC receiving IMRT and to ifnd a suitable cut?off value of GTV?P for prognosis prediction. Methods:Clinical data of 358 patients with locally advanced NPC who received IMRT were reviewed. Receiver oper?ating characteristic (ROC) curves were used to identify the cut?off values of GTV?P for the prediction of different end?points [overall survival (OS), local relapse?free survival (LRFS), distant metastasis?free survival (DMFS), and disease?free survival (DFS)] and to test the prognostic value of GTV?P when compared with that of the American Joint Committee on Cancer T staging system. Results:The 358 patients with locally advanced NPC were divided into two groups by the cut?off value of GTV?P as determined using ROC curves: 219 (61.2%) patients with GTV?P≤46.4mL and 139 (38.8%) with GTV?P>46.4mL. The 3?year OS, LRFS, DMFS, and DFS rates were all higher in patients with GTV?P≤46.4mL than in those with GTV?P>46.4mL (allP<0.05). Multivariate analysis indicated that GTV?P>46.4mL was an independent unfavorable prognostic factor for patient survival. The ROC curve veriifed that the predictive ability of GTV?P was superior to that of T category (P<0.001). The cut?off values of GTV?P for the prediction of OS, LRFS, DMFS, and DFS were 46.4, 57.9, 75.4 and 46.4mL, respectively. Conclusion:In patients with locally advanced NPC, GTV?P>46.4mL is an independent unfavorable prognostic indi?cator for survival after IMRT, with a prognostic value superior to that of T category.
3.Effect of super early rehabilitation care on patients with cerebral apoplexy
Xiaoqiong JIN ; Xinqiong CHEN ; Si LIN ; Linlin YE ; Han YU ; Cong XU ; Wumin ZHOU
Chinese Journal of Modern Nursing 2014;20(4):373-375
Objective To discuss the effect of super early rehabilitation care on daily life ability for patients with cerebral apoplexy .Methods A total of 120 cases of stroke patients were randomly divided into the control group and the experimental group with 60 cases in each group .The control group was given routine nursing, and the experimental group was given super early rehabilitation care .Using self-designed questionnaire , patients’ knowledge of health education and satisfaction towards nursing quality were evaluated , by internationally accepted Modified Barthel Index (MBI) and simplified Fugl-Meyer Assessment(FMA) to evaluate the patient’s motion function and daily living skills .Results The comparison of the two groups in stroke health education knowledge and patient’s satisfaction has a significant difference (90.0%vs 63.33%;95.0%vs 81.67%;χ2 =10.253,9.677,respectively;P<0.05);after four weeks, the patients in experimental group FMA score and MBI score were significantly higher than those in control group [(55.2 ±5.1) vs (36.5 ±4.2);(62.9 ±9.8) vs (42.3 ±10.6);t=3.25,3.17,respectively;P<0.05)].Conclusions Super early comprehensive rehabilitation nursing can reduce disability in patients with cerebral apoplexy , shorten the course of the disease , significantly improve stroke patients with hemiplegia limb function and ADL ability , and reduce morbidity .