Cell biology is a basic medical subject,and one of earliest learned subjects concerning medical science. The teacher's teaching methods will directly influence students' interest and score. In the article we have compared the two teaching methods, the traditional method regarding teachers as dominating part and self-teaching method regarding teachers as subordinate part. The conclusion has showed that the self-teaching method can improve students' score and easily be accepted by students, compared with traditional teaching method. However,it can not be used too frequently.