OBJECTIVETo evaluate the cross-leg flap for repairing the soft tissue defect of the leg.

METHODSTwenty-tree patients with exposure wounds on the leg were selected for the treatment by using different kinds of the cross-leg flaps, including 5 in medial knee skin flap, 12 in gastrocnemius myo-cutaneous flap and 6 in posterior calf fascial skin flap.

RESULTSThe patients were successfully treated with the complete survival of the flaps. No infection occurred. The results were good with the long-term follow-ups.

CONCLUSIONThe method of the cross-leg flap is a safe and good way for repairing the soft tissue defects of the leg with the advantages such as color and texture of the transplanted tissue to be matched the recipient well.

Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Humans ; Leg Injuries ; surgery ; Male ; Middle Aged ; Reconstructive Surgical Procedures ; methods ; Skin Transplantation ; methods ; Surgical Flaps ; Transplantation, Autologous ; Treatment Outcome ; Wound Healing

OBJECTIVETo observe the postburn changes in the plasma levels of ICAM-1, IL-10 and TNFalpha during early postburn stage.

METHODSNineteen burn patients were enrolled in the study. The plasma levels of the above 3 kinds of factors were determined with ELISA in the peripheral plasma of the patients, plasma samples from 11 healthy volunteers were taken as the control.

RESULTSThe plasma levels of ICAM-1, IL-10 and TNFalpha increased obviously postburn, especially in those patients who were complicated with hypovolumic shock, sepsis and MODS (P < 0.05 - 0.01).

CONCLUSIONThe monitoring of the postburn changes in plasma levels of ICAM-1, IL-10 and TNFalpha might be helpful in the forecast of postburn sepsis and the development of MODS.

Adult ; Burns ; immunology ; Female ; Humans ; Intercellular Adhesion Molecule-1 ; blood ; Interleukin-10 ; blood ; Male ; Middle Aged ; Multiple Organ Failure ; immunology ; Sepsis ; immunology ; Shock ; immunology ; Time Factors ; Tumor Necrosis Factor-alpha ; analysis