1.Analysis ofZhangZhong-jing’s Acupuncture-moxibustion Treatment Characteristics and Academic Thought
Shanghai Journal of Acupuncture and Moxibustion 2016;35(8):1013-1015
This article sorts out and analyzes acupuncture-moxibustion items inTreatise on Cold Damage DiseasesandSynopsis of Prescriptions of the Golden Chamberand proposes regularities in application of and the characteristic ofZhangZhong-jing’s acupuncture and moxibustion. Acupuncture was often used for unblocking and regulating meridional qi and clearing and purging excessive heat. Moxibustion was often used for warming yang and remedying deficiency or dispersing and unblocking yang qi. Because of convenient operation, acupuncture-moxibustion therapy was often used to treatdangerous and serious diseases. Acupuncture and moxibustion were often combined with herbal prescriptions and other therapeutic methods to improve therapeutic effects, especially on difficult and complicated diseases.ZhangZhong-jing’s guiding thought ofacupuncture-moxibustion treatment first advocates treatment of diseases from the root and meanwhile, pays attention to treatment of both symptoms and causes of diseases. Secondarily, it emphasizes acupuncture-moxibustion treatment based on syndrome differentiation and especially values pulse condition, meridians and acupuncture points. It has abundant contents in treating the same disease with different methods and often selects specific acupoints. Thirdly, it favours preventive treatment of diseases, andwhether prevention of diseases before they arise or prevention of diseases from exacerbating was embodied in his acupuncture-moxibustion treatment.
2.Outcomes analysis after vitrectomy of polypoidal choroidal vasculopathy combined with vitreous hemorrhage
Chinese Journal of Postgraduates of Medicine 2013;36(24):10-12
Objettive To evaluate the effect of taking vitrectomy on the patients who suffer from polypoidal choroidal vasculopathy (PCV) combined with vitreous hemorrhage (VH),observe the natural consequence of PCV combined with VH and analyze the factors that affected the visual prognosis.Methods The clinical data of 20 patients with PCV combined with VH who performed vitrectomy were analyzed retrospectively from January 2009 to September 2012.Best corrected visual acuity (BCVA) was compared before and after operation,and explored the factors that affected the visual prognosis.Results Patients were followed up 6-18 (13 ± 2) months.At the last follow-up,BCVA was improved and better than 0.05 in 11eyes.There was significant difference in BCVA between before operation (2.91 ±0.52) and 2 weeks after operation (1.52 ±0.51)(P =0.003).The natural factors between visual acuity improved patients and non-improved patients were compared,follow-up treatment and the condition of macular was the independent factor that affected the visual prognosis (P =0.009,0.034).There was significant difference in BCVA of 6months after operation between patients with follow-up treatment (photedynamic therapy or transpupillary thermotherapy,10 cases) and patients without follow-up treatment (10 cases)(0.77 ± 0.51 vs.1.43 ± 0.64)(P =0.035).Conclusions Vitrectomy can significantly improve the visual acuity of PCV combined with VH.It will get better visual acuity,if has photodynamic therapy or transpupillary thermotherapy postoperatively.
3.Relationship between Heart Rate Variability and Cold-Heat/Deficienc y-Excess Syndromes in TCM
Journal of Traditional Chinese Medicine 1993;0(04):-
Objective To study the characteristics of heart rate variabili ty (HRV) in states of calm supine position, supine position and counting, and ca lm upstanding position, and the relationship with TCM syndromes of cold-h eat and deficiency-excess. Methods Totally 233 patient s diagnosed by TCM & western medicine with different syndromes were divided into five groups. B y comparing the general changes of frequency domain of HRV under three kinds of condition s, the variation of HRV indexes was measured in the excess heat syndrome group ( 64 cases), deficiency cold syndrome group (16 cases), cold-heat complex syndrom e group (38 cases), yin deficiency with fire syndrome group (67 cases), and defic iency of both yin and yang syndrome group (48 cases). Results The low frequenc y (LF) and low frequency normalized unit (LFNU) manifested sympathetic nervous a ctivity were augmented and were related with the yang syndrome and heat syndrome obvi ously. The high frequency (HF) and high frequency normalized unit (HFNU) manifes ted parasympathetic nervous activity were augmented and were related with the yi n syn drome and cold syndrome. The increased LF/HF reflected the yang syndrome and hea t syndrome. The decreased LF/HF reflected yin syndrome and cold syndrome. The co ndition of counting had a weighing influence on the diagnosis of yang syndrome a nd heat syndrome. And the condition of upstanding played a weighing role in defi ciency syndrome and cold syndrome. Conclusion The law o f changes of HRV under three kinds of condition is helpful in syndrome differentiation of cold-heat an d deficiency-excess.
4.Tamsulosin hydrochlorid combined with Qianlie'an Shuan in treatment of chronic pelvic pain syndrome
Xinhui XIA ; Li HE ; Xuarn SUN
Chinese Journal of General Practitioners 2011;10(10):740-741
Total 150 patients with chronic pelvic pain syndrome were randomly divided into three groups with 50 cases in each group. Patients were treated with tamsulosin, Qianlie'an Shuan and tamsulosin plus Qianlie'an Shuan for 12 weeks, respectively. Patients were assessed with the National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) before and after treatment. The score of NIH-CPSI decreased from 25. 1 ± 2. 2 to 19. 5 ± 1.7 after treatment in tamsulosin group; 25.0 ± 2. 2 to 19. 1 ± 1.7 in Qianlie'an Shuan group, and 24. 8 ± 1.7 to 16. 8 ± 1.4 in combined therapy group, all P <0. 01. The results indicated that tamsulosin, Qianlie' an Shuan or combined therapy were all effective in alleviating the symptoms and improving the quality of life, and the combined therapy was superior to single therapy in relief of symptoms.
5.Study of Pharmacy Elective to Medical Student
Dan HE ; Qi FAN ; Xinhui JIANG ; Hua ZHAO
Chinese Journal of Medical Education Research 2005;0(05):-
It is necessary to medical student to take the elective course of pharmacy.This paper put forward several viewpoints and concrete methods about teaching methods,means and contents of elective course of pharmacy.
6.KRT 9 Gene Mutations in Three Chinese Pedigrees with Epidermolytic Palmoplantar Keratoderma
Wei MAO ; Xinhui HE ; Xianning ZHANG ; Zhilong YAN ; Xianglei HE ; Hengping CHEN ; Lairong XU
Chinese Journal of Dermatology 2003;0(09):-
Objective To investigate the keratin 9 gene mutation in epidermolytic palmoplantar keratoderma (EPPK) and its relationship with clinical manifestations. Methods Three Chinese pedigrees with EPPK were studied. Polymerase chain reaction (PCR) was performed to amplify the seven exons encoded by keratin 9. Denaturing high-performance liquid chromatography (DHPLC), DNA sequencing and allele-specific PCR were used to reveal the sequence variation in the PCR products. Results An insertion-deletion mutation in the exon 1 of keratin 9 497delAinsGGCT, was revealed in all 3 EPPK families, resulting in the keratin 9 change from tyrosine166 to tryptophan and leucine (Y166delinsWL). Allele-specific PCR confirmed that the mutation was not a commonly seen polymorphism, but a novel mutation which has not been reported in The Human Intermediate Filament Mutation Database (http://www.interfil.org). Conclusions A new keratin 9 gene mutation, 497delAinsGGCT, is found in these Chinese EPPK pedigrees, which may be the genetic basis of EPPK.
7.The efficacy of calcined natural bovine bone(CBB)in the treatment of bone defects in animal
Yue HE ; Zhiquan TIAN ; Liang WANG ; Yang YAO ; Lu YANG ; Wentao HUANG ; Xinhui HUANG
Journal of Practical Stomatology 2015;(2):167-170
Objective:To observe the efficacy of calcined bovine bone(CBB)in the repair of animal bone defects.Methods:Ca-nine alveolar bone defect model,rat and rabbit calvarial critical size defect models were established respectively.All animals were randomly divided into 2 groups(n=6).The defects in the experimental group were repaire with CBB,those in the control group were not treated.The effects were observed by HE staining,Micro CT and Masson trichrome staining.Results:Canin alveolar bone de-fects were well repaired 8 week after operation.The skull defects in rabbits and SD rats were replaced by new bone 1 2 and 8 weeks after operation respectively.In all the control groups bone defects were not healed or not completely repaired.Conclusion:CBB is ef-fective in the repair of bone defects.
8.Effects of Soothing Liver and Activating Blood Chinese Medicine on Myocardial Cell Apoptosis and Related Gene Expression of BMSCs Transplanting Myocardial Ischemia Reperfusion Injury Rats
Xinhui LI ; Zhengde HUANG ; Jianfang DU ; Xuejiao XIE ; Liqing SU ; Yirong HE
Chinese Journal of Information on Traditional Chinese Medicine 2015;(3):56-59
Objective To investigate the effects of soothing liver and activating blood Chinese medicine on myocardial cell apoptosis and related gene expression of BMSCs transplanting on myocardial ischemia reperfusion injury (IRI) of rats;To discuss its mechanism of protecting myocardium. Methods Model of myocardial IRI was established in rats. BMSCs were isolated, cultivated, and transplanted in IRI rats. SD rats were randomly divided into sham-operation group, IRI group, BMSCs group, and combined group. Rats in combined group received gavage with soothing liver and activating blood Chinese medicine, while rats in other groups received gavage with the same dose of normal saline. After 4 weeks, myocardial cell apoptosis, Bcl-2, and Bax protein expression in myocardial cells were detected by TUNEL method and immunohistochemical method. Results Compared with IRI group, myocardial cell apoptosis index in the combined group and BMSCs group was lower, Bax expression decreased, Bcl-2 expression significantly increased (P<0.01);Compared with BMSCs group, myocardial cell apoptosis index in the combined group was lower;Bax expression decreased, Bcl-2 expression increased (P<0.05, P<0.01). Conclusion Soothing liver and activating blood Chinese medicine can inhibit BMSCs transplantation in IRI rat myocardial cell apoptosis, promote myocardial regeneration, and protect myocardial cells.
9.Comparative study of woman false positive rate in exercise treadmill before or after menopause
Xiaopeng ZHAO ; Dayuan HE ; Guangyu AN ; Jianghong ZHENG ; Xinhui KOU ; Dongqing HU
Chinese Journal of Postgraduates of Medicine 2009;32(z2):48-49
Objective To analyse the rate of coincidence to suspected coronary artery disease (CAD) patient between positive exercise treadmill testing (TET) and coronary angiography (CAG) test.Method Two hundred and sixty-eight chest pain patients positive in TET were performed CAG test,coronary stenosis exceed 50% was diagnosed CAD. Results One hundred and seventy-six patients (65.67%) was diagnosed by CAG, 105 male and 71 female in them. Ninety-two (34.33%) patients was negative in CAG test. The false positive rate of TET between post-menopause patients (30.12%, 25/83 ) andmale patients (28.08%, 41/146) was no significant difference(P > 0.05 ); the difference of false positive rate between pro-menopause patients (66.67%, 26/39) and male patients (28.08% ,41/146) was statistical significance (P < 0.01 ). Conclusions The positive rate of CAG can be greatly improved by screening the chest pain patients though TET before CAG, if the positive in TET performed CAG only. TET false positive rate of pro-menopause female is significantly higher than post-menopause female or male.
10.Perioperative risk factors for postoperative pancreatic fistula in patients with gastric cancer
Huazhou ZHAO ; Ting WANG ; Xinhui ZHANG ; Ruijun LIU ; Zhiyu CAO ; Bo YANG ; Jianmiao HE
Clinical Medicine of China 2016;32(10):924-928
Objective To explore perioperative risk factors for postoperative pancreatic fistu?la. Methods Six hundred and forty?three cases patients who underwent radical gastrectomy for gastric cancer from January 2010 to June 2015 in the NO. 309 Hospital of Chinese People’ s Liberation Army were selected and divided into Postoperative Pancreatic Fistula( POPF) group with 53 cases and Non?Postoperative Pancreatic Fis?tula( NPOPF) group with 590 cases. Preoperative,intraoperative and postoperative data were analyzed by statisti?cal analysis of two groups. Results POPF rate was 8. 24%(53/643). There were no significanct differences in terms of gender,age,preoperation with disease,preoperative serum albumin,TNM stage,abdominal surgery,sur?gical procedure,lymph node dissection,digestive tract reconstruction,surgical approach,blood loss and length of time between the POPF group and NPOP group(P>0. 05). The level of BMI of POPF group was higher than that of NPOPF group,the difference was statistically significant((25. 63±2. 54) kg/m2 vs. (21. 11±2. 44) kg/m2,t=2. 245,P=0. 025). The number of lymph node dissection in POPF group was (32. 25±5. 82),in NPOPF group was (27. 06±6. 79),there was significant difference between the two groups(t=2. 093,P=0. 037). The operation time in POPF group was (242. 50±52. 30) min,in NPOPF group was (229. 51±59. 21) min,the difference was statistically significant between the two groups( t=2. 398,P=0. 017) . The serum CRP of 1 d in POPF group was (85. 72±12. 05) mg/L,in NPOPF group was (76. 41±12. 52) mg/L,and there was significant difference between the two groups( t=1. 979,P=0. 048) . The serum albumin of 2?4 d after operation in POPF group was (26. 0±5. 9) g/L,in NPOPF group was (32. 6±6. 8) g/L,the difference between the two groups was statistically significant(t=-10. 185,P=0. 000). The drainage fluid amylase of 1 and 2 d after operation in POPF group was (2094+1444) U/L,in NPOPF group was (746+486) U/L,and there was significant difference be?tween the two groups( t=10. 400,P=0. 000) . Logistic regression analysis results showed that body mass index ( BMI) ,lymph node dissection number,time of operation,postoperative 1,2 d drainage fluid amylase and serum albumin of 2?4 d after operation were postoperative occurred pancreatic fistula risk factors( OR=1. 972,183. 6, 2. 004,0. 150,9. 809,P>0. 05). Conclusion BMI,number of dissected lymph node,duration of surgery,serum albumin of 2?4 d after operation and postoperative 1,2 d drainage fluid amylase have important clinical values for predicted POPF.