Objective To investigate the effect of percutaneous coronary intervention (PCI) on left ventricular remodeling and cardiac function in patients with myocardial infarction.Methods A total of 90 myocardial infarction patients in our hospital were as the research objects,a total of 45 cases underwent PCI surgery were in observation group,another 45 cases undergoing elective PCI surgery were in control group.The levels of N-terminal pro brain natriuretic peptide (NT-proBNP),norepinephrine (NE) and epinephrine (E),plasma renin (PRA),angiotensin Ⅱ (Ang Ⅱ),aldosterone (ALD) were detected before operation and on the first postoperative day.After 6 months of follow-up,the incidence of heart failure of two groups were compared.Results There was no significant difference between the two groups in preoperative NT-proBNP,NE,E,PRA,Ang Ⅱ and ALD levels (P ＞0.05),the observation group had decreased NT-proBNP,NE,E,PRA,Ang Ⅱ,ALD levels at 1 d after operation than operation before and the control group (P ＜ 0.05).At 1 month after surgery,the observation group had lower LVDEd,LVSEd,LAd,and higher LVEF than treatment before and control group (P ＜ 0.05).The incidence of heart failure after 6 months in the observation group and the control group was 1 1.1％,2 4.4 ％ respectively,and the difference was statistically significant (x2 =7.31,P ＜ 0.05).Conclusion Percutaneous coronary intervention (PCI) timing can affect the prognosis of patients with myocardial infarction.Compared with elective PCI,emergency PCI can inhibit the RAAS system and sympathetic activation,improve ventricular remodeling and left ventricular function after myocardial infarction,and reduce the incidence of secondary heart failure.

Objective To investigate the effect of percutaneous coronary intervention (PCI) on left ventricular remodeling and cardiac function in patients with myocardial infarction.Methods A total of 90 myocardial infarction patients in our hospital were as the research objects,a total of 45 cases underwent PCI surgery were in observation group,another 45 cases undergoing elective PCI surgery were in control group.The levels of N-terminal pro brain natriuretic peptide (NT-proBNP),norepinephrine (NE) and epinephrine (E),plasma renin (PRA),angiotensin Ⅱ (Ang Ⅱ),aldosterone (ALD) were detected before operation and on the first postoperative day.After 6 months of follow-up,the incidence of heart failure of two groups were compared.Results There was no significant difference between the two groups in preoperative NT-proBNP,NE,E,PRA,Ang Ⅱ and ALD levels (P ＞0.05),the observation group had decreased NT-proBNP,NE,E,PRA,Ang Ⅱ,ALD levels at 1 d after operation than operation before and the control group (P ＜ 0.05).At 1 month after surgery,the observation group had lower LVDEd,LVSEd,LAd,and higher LVEF than treatment before and control group (P ＜ 0.05).The incidence of heart failure after 6 months in the observation group and the control group was 1 1.1％,2 4.4 ％ respectively,and the difference was statistically significant (x2 =7.31,P ＜ 0.05).Conclusion Percutaneous coronary intervention (PCI) timing can affect the prognosis of patients with myocardial infarction.Compared with elective PCI,emergency PCI can inhibit the RAAS system and sympathetic activation,improve ventricular remodeling and left ventricular function after myocardial infarction,and reduce the incidence of secondary heart failure.