1.Application of robotic surgery in otolaryngology-head and neck surgery
Yanyan NIU ; Xingming CHEN ; Zhiqiang GAO
Basic & Clinical Medicine 2006;0(05):-
Robotic Surgery is a novel minimally invasive surgery which is advanced from the endoscopic surgical techniques.This new technique has a promising future to be applied in clinics because of the distinct and compelling advantages compared with the traditional endoscopic surgery,including true three-dimensional endoscopic vision,increased freedom of movement of instruments and tremor filtration.We review the potential applications,advantages,limitations of the da Vinci Surgical System in otolaryngology.
2.Research progress of the methods and applications of micronucleus assay
Si CHEN ; Keqing LU ; Xingming MA
Chinese Journal of Comparative Medicine 2016;26(2):83-86
Micronucleus ( MN) assay as a routine examination for genotoxicity has been widely used.The testing specimens were taken from bone marrow and extended from blood and tissues.In addition to testing genotoxicity of drugs, it is also applied in disease diagnosis for genetic mutation, evaluation of curative effectiveness and disease prevention. Moreover, MN assay is also an important safety indicator for drugs and health foods registration.This review will discuss the staining method of MN test and its application in the field of diseases and virology.
3.Relationship of lipids disorder with sex and hypertension in diabetic patients
Hua JING ; Zhangrong XU ; Xingming CHEN
Chinese Journal of Practical Internal Medicine 2001;0(07):-
Objective To investigate the prevalence of lipids disorder in patients with diabetes and the relationship of lipids disorder with sex and hypertension.Methods Totally 2 545 diabetic patients were analyzed for their different lipids disorder based on the clinical data.Results In the group of diabetic patients,1 663 cases were found with lipids disorder (65.3%),and females and males with lipids disorder were 69.6% and 61.9% respectively (P
4.Analysis of risk factors for postoperative pulmonary complications In elderly patients with esophageal cancer aged 70 years and over
Xun YANG ; Jie WU ; Qixun CHEN ; Xingming ZHOU
Chinese Journal of Geriatrics 2009;28(1):33-36
Objective To analyze the risk factors for postoperative pulmonary complications (PPCs) in elderly patients with esophageal cancer aged 70 years and over. Methods 185 elderly patients aged 70 years and over after esophagectomy were retrospectively analyzed. Univariate and multivariate logistic regression analysis were used to examine the risk factors for PPCs and related mortality. Results In 185 elderly patients from 70 to 86 years of age with a median age of 72 years, PPCs occurred in 36 patients(19.5%) including pneumonia in 23(63.8%) cases, atelectasis in 3 (8.3%) cases, adult respiratory distress syndrome (ARDS) in 2(5.5%) cases, pulmonary embolism in 1(2.7%) case and respiratory failure in 7(19.4%) cases. The related mortality was 5.9% (11cases) and the causes of death were pneumonia (4 cases), ARDS (1 case), pulmonary embolism (1case) and respiratory failure (5 cases). There were 43 (23.2%) cases with the forced expiratory volume in one second (FEV1%)< 65% before operation. The bleeding volume during operation ranged from 200ml~2000 ml, with a mean volume of about 350ml, and was above 800ml in 8(4.3%) cases. Injury of recurrent laryngeal nerve during operation occurred in 13(7.0%) cases. Univariate and multivariate logistic regression analysis indicated that smoking, obesity, poor preoperative pulmonary function (FEV1 % < 65%), bleeding volume over 800ml during operation and injury of recurrent laryngeal nerve were the independent risk factors for PPCs in elderly patients with esophageal cancer aged 70 years and over. Poor preoperative pulmonary function (FEV1% < 65%)(OR=29.49, P=0.023), bleeding volume over 800ml during operation(OR=32.93, P=0.011) and injury of recurrent laryngeal nerve(OR= 10.14, P= 0.034) were also the independent risk factors for related mortality of PPCs. Conclusions The high risks of PPCs and related mortality in elderly patients with esophageal cancer are not only due to the physiological and pathological characteristics of elderly people, but also due to the operative manipulation.
5.Development of Portable Multi-function Heart-Sound Auscultating System
Qingfeng LIAO ; Xingming GUO ; Jian ZHANG ; Ke CHEN ; Jing LUO
Chinese Medical Equipment Journal 2004;0(09):-
Objective To overcome the disadvantages of the traditional auscultating method and design the electro-auscultating visual system integrating the monitoring and recording functions.Methods The portable system consisted of the module pre-gathering and electro-auscultating heart-sound signal,the circuit of A/D converting and MCU,as well as the device of signal LCD-displaying in real-time and the USB mass storage device.Results Portable electro-auscultating system was realized,which integrated the functions of watching,monitoring and recording.Conclusion The portable system is more convenient for clinical doctors to get correct information from patients,benefiting to the clinical pathology-statistics and profound development of the related data.
6.Clinical study of cervical esophagogastrostomy with mechanical stapler in treatment of esophageal cancer
Youhua JIANG ; Xingming ZHOU ; Qixun CHEN ; Fulai YAN
Cancer Research and Clinic 2008;20(4):244-246
Objective To contrast the efficacy of mechanical stapler and hand suture for cervical esophagogastrostomy in the treatment of esophayeal cancer.Methods From January 2001 to August 2007,217 cases of cervical esophagogastrostomy were done in esophageal carcinoma.Among them.136 cases were treated by mechanical stapler and 81 cases by hand.Results The incidence of anastomotic fistula was 2.2%(3/136)in mechanical stapler group and 11.1%(9/81)in the group by hand.There was significant difference between the two groups(P<0.95).The incidence of cervical incision infection was 2.9%(4/136)in mechanical stapler group and 14.8%(12/81)in the group by hand.There was significant difference between these two groups(P<0.05).There was no significant difference between these two groups about pulmonary infection,arrhythmia,chylothorax and laryngeal nerve injury.Conclusion The incidence of anastomotic fistula and cervical incision infection was reduced by mechanical stapler which was displayed to advantage in esophagogastrostomy.
7.Correlation between preoperative NLR, PLR, and RDW and clinical pathological param-eters in gastric cancer patients
Jing JIA ; Ying CHEN ; Lu LIN ; Lin WANG ; Dedong CHEN ; Xingming YE ; Yan CHEN
Chinese Journal of Clinical Oncology 2017;44(2):78-82
Objective:To assess the association between preoperative neutrophil–lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and red cell distribution width (RDW) and the tumor pathological features in gastric cancer (GC) patients. Methods: We re-viewed the records of 434 patients from 2012 to 2014 in Fujian Cancer Hospital. All patients were admitted to the hospital for the first time, and no patients received any cancer-specific pretreatment. For comparison, 309 age-and gender-matched healthy individuals who underwent annual physical examination at the hospital and 342 patients with chronic atrophic gastritis were enrolled. Results:GC patients had higher NLR, PLR, and RDW than the controls (P<0.000 1). Elevated NLR, PLR, and RDW were associated with the develop-ment of tumor stages as indicated by the Kruskal-Wallis analysis. However, no similar association was observed between the tumor dif-ferentiation grade and location and those three markers. Multivariate regression analysis further revealed that both NLR and PLR were independent predicting factors for either the tumor TNM or T stage (P<0.000 1). ROC curve analysis showed that NLR and PLR had a certain diagnostic effect on the preoperative T staging of GC. Conclusion:The preoperative NLR and PLR levels are closely correlated with the tumor TNM stages in GC patients. Both these parameters have potential values as markers to assist either in early diagnosis or preoperative tumor stage evaluation in GC.
8.Human resources integration within medical service teams for Beijing 2008 Olympic Games and Paralympic Games
Jun MA ; Jianping DAI ; Chaoying LV ; Xingming SUN ; Jinjun ZHANG ; Zhi CHEN
Chinese Journal of Hospital Administration 2009;25(6):368-371
Building of medical teams was a basic preparation for Beijing 2008 Olympic Games and Paralympic Games as well. In this consideration, the Beijing Organizing Committee for the Olympic Games (BOCOG) and Beijing Health Bureau developed a complete set of mechanism to integrate human resources, coveting standards development, selection, training and testing for members of medical teams. This ensures the success of medical services delivery and provides medical services delivery of subsequent Large-scale activities with valuable experiences as well
9.Study on difference of noninvasive blood pressure measurement method based on oscillometric and auscultatory
Jumei ZHANG ; Xihan ZHANG ; Yan YAN ; An JI ; Min CHEN ; Xingming GUO
Chinese Medical Equipment Journal 2004;0(07):-
This paper introduces and compares several blood pressure measurements, among which two noninvasive blood pressure measurements based on oscillometric and auscultatory methods are mainly compared. It also analyses the characteristics and advantages of oscillometric method as well as introduces a noninvasive blood pressure measurement monitor based on oscillometric. By using this monitor and a common auscultory method, we conducted a public survey. The result for statistical data analysis showed that the difference between oscillometric and auscultatory methods are quite small, and the accuracy of them are both quite good .This paper also previews the future of the noninvasive blood pressure measurement
10.Alteration levels of IL-17 and IL-19 inflammatory factors among deadaptation personnel from the plateau
Xingming QU ; Binfeng HE ; Hongping CHEN ; Shengxue SHI ; Guisheng QIAN ; Guansong WANG
Military Medical Sciences 2014;(10):768-770,779
Objective To analyze the change in the concentration of IL-17 and IL-10 inflammatory factors among the deadaptation personnel who returned from the plateau.Methods A total 21 healthy males were investigated who averaged 25 years in age, lived permanently in the plains (200 m), and once stayed to the plateau (Lasha) for 6 months.Their venous blood was collected at three time points:the day before ascending to the plateau(control), the second day after return to the plains(d2) and the 30th day(d30), respectively.Their serum was seperated from the whole blood and the level of IL-17A and IL-10 was detected by ELISA method.Results The concentration of IL-17A and the IL-17A/IL-10 ratio were significant increased at d2 and d30, respectively, compared with control (P<0.05).Compared with d2, IL-17A and the IL-17A/IL-10 ratio were decreased obviously at d30(P <0.05).The level of IL-10 at d2 and d30 was significantly reduced compared with control ( P <0.05), but increased at d30 compared with d2.Correlative analysis showed that there was a negative correlation in the levels of IL-10 and IL-17A between control, d2 and d30, respectively (r1=0.948, P<0.05;r2=0.969, P<0.05;r3=0.972, P<0.05).A significant negative correlation was observed in the alteration levels of IL-10 and IL-17A between the three groups(r4=-0.793, P<0.05; r5=-0.756, P<0.05). Conclusion The concentration of inflammatory factors among the plateau deadaptation patients is imbalanced, but it is gradually reduced with time.The mechanism is still not clear.