1.Determination of Gallic Acid in Gongyanping Dispersible Tablet by HPLC
Donghui LIU ; Xingmiao GU ; Dongsheng YUAN ; Xinxin ZHOU
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(04):-
Objective To establish a method for the determination of gallic acid in Gongyanping Dispersible Tablet by HPLC.Method A HPLC method was performed on Hypersil ODS column(4.0?250 mm,5 ?m).The mobile phase was acetonitrile(0.2 %CH3OH)-water solution of 0.1 %triethylamine and 0.1 %phosphoric acid(1 ∶99).The detection wavelength was 220 nm and flow rate was 1.0 mL/min.Results Gallic acid showed a good linearity in the range of 0.022~0.352 ?g,r=0.999 9.The average recovery was 99.70 %,and RSD was 1.61 %.Conclusion This method is effective and can be used for the quality control of Gallic acid in Gongyanping Dispersible Tablet.
2.Determination of Geniposide in Bazheng Dispersible Tablet by HPLC
Xingmiao GU ; Donghui LIU ; Ya CHEN ; Xinxin ZHOU ;
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(06):-
Objective To establish a method for the determination of geniposide in Bazheng Dispersible Tablet by HPI,C. Methods The HPLC was performed on a Hypersil ODS column(250 mm?4 mm,5?m).The mobile phase was acetoni- tril-water(11:89).The detection wavelength was at 238 nm and flow rate was 1.0 mL/min.Results Geniposide showed a good linearity in the range of 0.046~0.46?g,and r=0.999 9.The average recovery was 99.54%,and RSD was 1.42%。Conclusion This method is accurate and can be used for the quality control of Bazheng Dispersible Tablet.
3.Determination of Danshensu in Xingkening Capsules by HPLC
Donghui LIU ; Yitian HUANG ; Xinxin ZHOU ; Xingmiao GU ; Yihua XIONG
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(02):-
Objective To determinate the content of Danshensu in Xingkenin g Capsules by HPLC.Methods HPLC with Hypersil ODS2 column was used, MeOH- 1 % acetic acid( 12:88) as a mobile phase and detection wavelength at 280nm.Re sults The linear range of Danshensu was in the range of 0.256~ 1.278 ? g. Th e average recovery of Danshensu was 102.73 % with a RSD of 1.34 % .Conclusio n The method is simple with a good reproducibility and can be used for the qu ality control of Xingkening Capsules.