Objective To discuss the efficacy of neural endoscopic and surgical operation in patients with cerebral hemorrhage induced by hypertension.Methods Sixty cases with cerebral hemorrhage induced by hypertension admitted at the People′s Hospital of Bortala from January 2015 to June 2016 were divided into the control group(n=32) and research group(n=28) according to cerebral hemorrhage surgical method.The patients of the control group were given conventional surgical operation treatment while the observation group were given neural endoscopic treatment.The operative time and intraoperative blood loss,and situation of hematoma absorption before and after operation and prognosis between the two groups were compared.Results The operative time and intraoperative blood loss of the two groups were respectively (132.6±35.4) min,(49.8±12.3) ml and (236.5±46.2) min,(263.5±49.8) ml,the observation group were obviously lower than that of the control group,the differences were statistically significant(t=6.532,9.548,all P<0.05).The preoperative hematoma volume,postoperative hematoma volume and hematoma clearance of the two groups were respectively (6.8±1.5) ml,(82.7±6.3)% and (16.3±3.1) ml,(57.8±5.2)%,the postoperative hematoma volume of observation group were obviously lower than that of the control group while the hematoma clearance obviously increased,the differences were statistically significant(t=6.584,-5.263,all P<0.05).The ADL assessment in patients of observation group was better than the control group and the death rate was lower than that of control group,the differences were statistically significant(3.6%(1/28) vs.21.9%(7/32),χ2=10.580,4.329,all P<0.05).Conclusion The efficacy of neural endoscopic applied in patients with cerebral hemorrhage induced by hypertension is remarkable,it causes little damage to the body and can obviously improve the effect of prognosis,it is worth popularization and application.

This study was conducted to examine the effectiveness of a gene transfer of human TGF beta 1 gene into smooth muscle cells and whether the TGF beta 1 can increase elastin expression of smooth muscle cells. With the help of DOTAP, smooth muscle cells were transfected with pMAMneoTGF beta 1. The positive cell clones were selected with G418. The stable transfection and expression of TGF beta 1 in the smooth muscle cells were determined by immunofluorescence analysis. The expression of elastin in the transfected and untransfected cells were determined by in situ hybridization. The adhesion force between smooth muscle cells and matrix was detected by micropipette system. The results showed abundant TGF beta 1 stable expression in smooth muscle cells. TGF beta 1 gene can increase two-three times elastin expression and increase the adhesion between smooth muscle cells and matrix. TGF beta 1 can be used in vascular tissue engineering to increase smooth muscle cells adhesion.
Cell Adhesion ; Cells, Cultured ; Elastin ; biosynthesis ; Humans ; In Situ Hybridization ; Muscle, Smooth, Vascular ; cytology ; metabolism ; Transfection ; Transforming Growth Factor beta ; biosynthesis ; genetics ; physiology ; Transforming Growth Factor beta1