1.Etiology of 96 syncope patients
Chinese Journal of Geriatric Heart Brain and Vessel Diseases 2017;19(9):971-973
Objective To study the diagnosis and treatment of syncope by analyzing its etiology.Methods Ninety-six syncope patients admitted to our hospital from 2014-01-01 to 2016-12-21were included in this study.The etiology of syncope was analyzed.Results Of the 96 syncope patients included in this study,50 (52.1 %) were diagnosed with nerve-mediated reflex syncope,31(32.3%) with orthostatic hypotensive syncope,10 (10.4%) with cardiogenic syncope due to arrhythmia,coronary atherosclerotic cardiopathy or pulmonary embolism,5 (5.2%) with other diseases.Conclusion Nerve-mediated reflex,orthostatic hypotension and cardiogenic factors are the causes of syncope.Attention should thus be paid to syncope caused by nervous system diseases.Clarification of the risk factors for syncope helps to reduce its potential risk.
2.Analysis of risk factors of early recovery in patients with ischemic stroke
Jing LIU ; Yan XING ; Huanhu LIU
Chinese Journal of Primary Medicine and Pharmacy 2012;19(12):1785-1786
Objective To investigate the risk factors of early recovery in patients with ischemic stroke(IS).Methods 168 patients with IS received the conventional treatment and early rehabilitation were enrolled in the study.Single factor analysis was used to analyze the risk factors of the IS in the early treatment of rehabilitation in patients with and without success recovery rehabilitation success,and then application (unconditional Logistic regression analysis factors early independent risk factors for healing.Results Single factor analysis shows that age quartile (60years old),history of hypertension,coronary heart disease,diabetes,history,history of smoking history,anxiety and depression and successful rehabilitation negatively,life,education degree by law quartile (12 years) and mental work positively correlated with successful recovery.Many factors analysis shows that education degree by quartile (12)(OR=0.12,95% 00.03 to 0.75),mental workers (OR=0.45,95% CI 0.37 to 0.47) is the success of the recovery protection factor (P<0.05),And age quartile (60) ( OR=2.12,95% CI 1.21 to 3.21 ),anxiety ( OR =2.64,95% CI 1.82 to 6.11 ) and depression (OR =1.45,95% CI 1.13 to 1.96) is the success of the recovery independent risk factors (P < 0.05 ).Conclusion Age quartile (60),anxiety and depression are IS successful independent risk factors for the recovery of the patients with early rehabilitation IS the risk factors should undertake the necessary intervention.
3.Determination of Luteolin-7-O-glucoside in Sedum Sarmentosum Bunge from Different Regions by HPLC
Yan LIU ; Caixia LIU ; Yuren XING
China Pharmacist 2016;19(3):584-585,586
Objective: To establish an HPLC method for the determination of luteolin-7-O-glucoside in Sedum Sarmentosum Bunge. Methods:The chromatographic column was Waters SymmetryShield C18(250 mm ×4.6 mm,5μm). The mobile phase consis-ted of tetrahydrofuran-methanol-water-phosphoric acid (9 ∶17 ∶74 ∶0. 25). The flow rate was 1. 0 ml·min-1. The detection wave-length was 350 nm. The chromatographic column temperature was 35℃. The injection volume was 10 μl. Results: The calibration curves were linear within the range of 5. 2-208. 0 μg · ml-1 ( r =0. 999 9 ) for luteolin-7-O-glucoside. The average recovery was 99. 12%(RSD=0. 94%,n=6). Conclusion:The method is simple, rapid, accurate, specific and repeatable. It can be used for the determination of luteolin-7-O-glucoside in Sedum Sarmentosum Bunge.
4.Application of silk fibroin in biomedical areas.
Huanyu JIN ; Xing LIU ; Hua YIN ; Yan AN
Journal of Biomedical Engineering 2014;31(1):228-232
For a long period of time, silk fibroin has been applied in biomedical areas. Along with the development of biotechnology, new functions of silk fibroin are being found and developed. From the suture of surgery to the therapeutic drug and the ordinary tissue engineering frame to high grade frame with drug buffer system, exploitation of silk fibroin is constantly introduced with something new from the old ones. In our review, we summarize the applications of silk fibroin in tissue engineering, drug buffer system and medical care.
Fibroins
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therapeutic use
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Humans
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Tissue Engineering
6.Evaluation and Clinical Value of Contrast-Enhanced Fluid-Attenuated Inversion-Recovery MR Imaging in Diagnosis of Leptomeningeal Metastasis
Journal of Practical Radiology 2000;0(12):-
Objective To explore the value of contrast-enhanced FLAIR imaging in diagnosis of leptomeningeal metastasis.Methods 23 cases of leptomeningeal metastasis with definite primitive-tumour were collected.All the cases were confirmed by clinic and laborotary examination.Of the 23 cases,7 cases underwent contrast-enhanced T1WI only,16 case underwent contrast-enhanced T1WI and FLAIR.Two groups were analyzed comparatively in diagnostic accuracy and displaying lesions between images of two sequence.Results(1)2 cases were missed,and 1 case was unsure diagnosed in T1WI contrast group;16 cases were all diagnosed accurately in both T1WI and FLAIR contrast-enhanced group.(2)11 cases with fine linear enhancement and 7 cases with small nodular enhancement were more obviously on contrast-enhanced FLAIR than that on contrast T1WI,but the thick linear enhancement were equal on two sequence.4 cases with more lesions were displayed on contrast-enhanced FLAIR images.The signal intensity on contrast FLAIR images were higher than that on contrast T1WI images at the same lesions.Conclusion Contrast-enhanced FLAIR has important value in diagnosing leptomeningeal metastasis.
7.Expression of AMCase mRNA in nasal mucosa of allergic rhinitis in SD rats.
Yan LIU ; Zhimin XING ; Min WANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(3):267-274
OBJECTIVE:
To examine AMCase mRNA expression levels in nasal mucosa of allergic rhinitis SD rats.
METHOD:
Thirty SD rats were chosen and randomly divided into the experimental group and the control group. 20 in experimental group and 10 in the control group. AR model rats were established through repeated intraperitoneal shot of ovalbumin (OVA) for 2 weeks and consequently confirmed by local challenge with OVA for 1 week. The control group was treated by the same method with Physiological saline water instead of OVA. After the last excitation allergic rhinitis was diagnosed according to the accumulation score about nasal symptom. The septal mucosa of all rats were used to diagnose pathologically by HE dyeing. AMCase mRNA in nasal mucosa, obtained from the bilateral nasal mucosa in two groups, were used to do reverse transcriptive polymerase chain reaction. Real-time polymerase chain reaction was used to examine AMCase mRNA expression levels.
RESULT:
(1) The results showed definitely that there were positive expression of AMCase mRNA in normal nasal mucosa. This expression increase significantly during nasal allergy (P < 0.05). (2) The increased expression of AMCase mRNA in allergic rhinitis are related with the nasal symptoms score (r = 0.411, P < 0.05).
CONCLUSION
Increased expression of AMCase mRNA in nasal mucosa in allergic rhinitis model might play roles in the pathogenesis of AR, and Restrain the enzyme activity could become new treatment targets of allergic rhinitis.
Animals
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Chitinases
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metabolism
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Nasal Mucosa
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metabolism
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Ovalbumin
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RNA, Messenger
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metabolism
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Rats
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Rats, Sprague-Dawley
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Rhinitis, Allergic
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enzymology
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metabolism
8.CHROMagar Candida medium for identification of Candida species:a systematic review
Xianguo XING ; Hui LIU ; Yan MENG
International Journal of Laboratory Medicine 2015;(18):2688-2690
Objective To evaluate the accuracy of CHROMagar Candida medium in identifying common Candida species .Meth‐ods Articles were extensively collected by searching the databases of MEDLINE and EMBase ,the Chinese Biomedical Database (CBM ) ,the Chinese Scientific Journals Database (CSJD) ,the Chinese Journal Full Text Database (CJFD) and through other ways . The qualities of these articles were assessed by using the quality assessment of diagnostic accuracy studies(QUADAS) .At last , summary receiver operating characteristic (SROC) curve was performed by the Meta‐Disc software ,so as to summarize diagnostic accuracy of CHROMagar Candida medium in identifying common Candida species .Results A total of 7 articles meeting all criteria were enrolled in this study .All 7 articles reported the accuracy of CHROMagar Candida medium in identifying the Candida albi‐cans ,the pooled sensitivity and specificity was 98 .3% and 98 .8% respectively ,and area under SROC curve (AUC) was 0 .998 0 .A‐mong them ,6 articles reported the accuracy of CHROMagar Candida medium in identifying Candida tropicalis ,the pooled sensitivity and specificity was 92 .5% and 99 .8% respectively ,and the AUC was 0 .998 3 .Among them ,5 articles reported the accuracy of CHROMagar Candida medium in identifying Candida Glabrata ,the pooled sensitivity and specificity was 98 .3% and 98 .7% respec‐tively ,and the AUC was 0 .996 8 .Conclusion CHROMagar Candida medium could quickly identify clinical common Candida species and results are reliable .
9.Diagnosis and therapy of dementia with Lewy bodies
Chunyan LIU ; Yan XING ; Yanfeng LI
Chinese Journal of Geriatrics 2017;36(4):367-370
10.Analysis the complications after trabeculectomy in 405 cases in department of ophthalmology
Xing-Yun, YAN ; Ping, HE ; Jing, LIU
International Eye Science 2015;(4):707-708
AIM: To analyze and summarize the effect of glaucoma trabeculectomy in the department of ophthalmology in basic hospital.
METHODS: Postoperative intraocular pressure ( IOP ) , filtering bleb and complications of 316 cases (405 eyes) of patients with glaucoma after trabeculectomy were analyzed.
RESULTS: After follow- up 12mo, 76. 5% IOP was controlled in normal level. 42. 5% was filtration bleb typeⅠ, 33. 1% typeII, 14. 6% in typeⅢand 9. 9% in typeⅣ. Intraoperative complication rate was 2. 5%, that was 31.4% at postoperative early stage ( before discharge ) , and 6. 7% at postoperative long - term ( 6mo after discharge) .
CONCLUSION:Trabeculectomy for glaucoma can better solve the problem of high IOP. It is more mature in primary hospitals, but there are still a variety of intraoperative and postoperative complications.