1.Discussion of Legal awareness training for medical students
Chinese Journal of Medical Education Research 2011;10(7):849-850
From the current reality of weak legal consciousness of medical students and based on summing up the training status on legal awareness of medical students in China, this paper proposes some countermeasures such as strengthening the educational work of training medical students' legal awareness,improving the cultivation of their spirit of the law and establishing the legal awareness of medical workers,etc.
2.Etiology of 96 syncope patients
Chinese Journal of Geriatric Heart Brain and Vessel Diseases 2017;19(9):971-973
Objective To study the diagnosis and treatment of syncope by analyzing its etiology.Methods Ninety-six syncope patients admitted to our hospital from 2014-01-01 to 2016-12-21were included in this study.The etiology of syncope was analyzed.Results Of the 96 syncope patients included in this study,50 (52.1 %) were diagnosed with nerve-mediated reflex syncope,31(32.3%) with orthostatic hypotensive syncope,10 (10.4%) with cardiogenic syncope due to arrhythmia,coronary atherosclerotic cardiopathy or pulmonary embolism,5 (5.2%) with other diseases.Conclusion Nerve-mediated reflex,orthostatic hypotension and cardiogenic factors are the causes of syncope.Attention should thus be paid to syncope caused by nervous system diseases.Clarification of the risk factors for syncope helps to reduce its potential risk.
3.Professor YAN De-xin's experience in diffrerentiating and treating emeda with heart involved from qi and blood
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(03):-
To introduce professor YAN De-xin's experience in diffrerentiating and treating Emeda with Heart Involved from qi and flood He thinks that pathogenesis of Emeda with Heart Involved is water overflowing due to yang deficiency,internal retention of blood stasis and turbidity.So this disease can be differentiated from these aspects including the disturbance of the functional activities of the lung,failure to transform body fluid;body fluid transformed by blood stasis,simultaneous disorders of both blood and body fluid;deficiency of pectoral qi,derangement of qi and blood.What's more,he proposes the application of drugs for warming yang and promoting blood circulation is very important.
4.Effects of CpG ODN on dendritic cells and its mechanisms
Chinese Journal of Pathophysiology 2000;0(07):-
Oligodeoxynucleotide containing unmethylated cytosine phosphate-guanosine motif(CpG ODN) may induce high expression of CD80, CD86, CD83, HLA I and HLAⅡ molecules on dendritic cells(DC) and stimulate DC to produce high level of IL-6, IL-12, TNF-? and IFN-?. CpG ODN is demonstrated in vivo to be a very potent adjuvant for Th1 cells, regulating Th0 cells to develop toward Th1 cells. Its role for DC is characteristics of CpG ODN sequence specificity and species specificity. CpG ODN is, at present, considered as a pathogen associated molecular pattern which binds its specific receptor,Toll-like receptor 9,then functions through TLR/IL-1R signaling pathway. It may represent a new therapeutic drug for broad applications in infectious disease, autoimmune disease, allergy and cancer therapy.
5.Effect of Oxcarbazepine on Serum Thyroid Hormones Levels of Children with Epilepsy
Journal of Applied Clinical Pediatrics 2004;0(12):-
0.05).Conclusions Long-term or short-term use of OXC can affect serum levels of thyroid hormones in children with epilepsy,so serum levels of thyroid hormones shall be monitored regularly in epileptic children treated with OXC.
6.Effect of Anti-Epileptic Drugs on Thyroid Structure and Endocrine Function in Rats
Journal of Applied Clinical Pediatrics 2006;0(17):-
0.05).Thyroid follicular volume of VPA group slightly reduced;thyroid follicular volume of OXC group increased while epithelial cells thinning;thyroid structure of LEV group had no alterations;thyroid follicular volume of OXC plus LEV group and VPA plus LEV group had no consistent alterations.Conclusions Long-term application of VPA and OXC may arouse alterations of thyroid structure and hormone secretion.LEV has no effection on thyroid function,with VPA and OXC combined usage can reduce their effection on thyroid gland.Thyroid hormone level should be monitored when using anti-epileptic drugs(ADES) long-term in clinical work.
7.Relationship between depressive symptoms and frailty among middle-aged and elderly populations
XING Yuping ; XING Hui ; LI Miao ; GAO Yan
Journal of Preventive Medicine 2024;36(8):649-653
Objective:
To investigate the relationship between depressive symptoms and frailty among middle-aged and elderly populations, so as to provide insights into the early identification and prevention of frailty.
Methods:
Based on the 2018 database of China Health and Retirement Longitudinal Study (CHARLS), demographic information, lifestyle and self-rated health status were collected from people aged 50 years and older. Depression symptoms were evaluated using the Short Version of Center for Epidemiological Studies Depression Scales (CES-D-10), and the frailty status was evaluated using frailty index. The relationship between depressive symptoms and frailty among middle-aged and elderly populations were using a multivariable logistic regression model, and the dose-response relationship was analyzed using a restricted cubic spline model.
Results:
A total of 5 172 individuals were enrolled, including 2 495 males (48.24%) and 2 677 females (51.76%), with a median age of 63.00 (interquartile range, 12.00) years, a median CES-D-10 score of 7.00 (interquartile range, 9.00) scores. There were 1 560 participants (30.16%) detected with mild depressive symptoms, 360 participants (6.96%) detected with moderate to severe depressive symptoms. Multivariable logistic regression analysis showed that after adjusting for gender, age, educational level, marital status, smoking, alcohol consumption and self-rated health status, participants who had mild depressive symptoms (OR=4.226, 95%CI: 3.625-4.928) and moderate to severe depressive symptoms (OR=10.737, 95%CI: 8.259-13.958) had a higher risk of frailty. The restricted cubic spline model showed a nonlinear relationship between depressive symptoms and frailty among middle-aged and elderly populations. When the CES-D-10 scores were greater than 7, the risk of frailty increased with higher CES-D-10 scores.
Conclusion
The degree of depressive symptoms in middle-aged and elderly people is associated with frailty, and there is a nonlinear relationship between the two.
9.Application of silk fibroin in biomedical areas.
Huanyu JIN ; Xing LIU ; Hua YIN ; Yan AN
Journal of Biomedical Engineering 2014;31(1):228-232
For a long period of time, silk fibroin has been applied in biomedical areas. Along with the development of biotechnology, new functions of silk fibroin are being found and developed. From the suture of surgery to the therapeutic drug and the ordinary tissue engineering frame to high grade frame with drug buffer system, exploitation of silk fibroin is constantly introduced with something new from the old ones. In our review, we summarize the applications of silk fibroin in tissue engineering, drug buffer system and medical care.
Fibroins
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therapeutic use
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Humans
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Tissue Engineering